" "
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Rapid, High Throughput Preformulation with Avacta’s Optim® 1000

Published: Thursday, October 25, 2012
Last Updated: Thursday, October 25, 2012
Bookmark and Share
A unique high throughput, micro-volume protein analysis and characterization system.

Avacta Analytical’s Optim® 1000 - a unique high throughput, micro-volume protein analysis and characterization system - is proving a valuable asset to scientists at the Macromolecule and Vaccine Stabilization Center (MVSC), University of Kansas, USA.

Professor C. Russell Middaugh explained: “Conventional analytical techniques used in preformulation, stability and formulation studies rely on methods that extrapolate partial data on slow and labour intensive instrumentation, making them incompatible with high throughput measurements and tight development timelines. We have developed a faster and more comprehensive approach, which depends on the measurement of all potential variables. The results are then processed mathematically using specially developed software, and are represented visually using empirical phase diagrams.”

“Ideally, a replicate series of results is acquired for each parameter and, although a variety of instruments can be used for individual measurements, this type of equipment tends to rely on relatively time-consuming processes and can generally handle only low throughputs. Sample volume is also an issue, since many conventional techniques require large amounts of the target molecule. The Optim 1000 provides rapid, multi-modal analysis of ultra-low sample volumes at high throughputs, precisely the kind of replicate measurements we need to generate data in a timely manner. Combining multiple technologies in a single instrument is already making in-roads into preformulation and formulation studies, and this approach is proving a real asset to researchers involved in the drug development process.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More Than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Avacta Sign Third Distribution Agreement with Pall Life Sciences
Deal marks Avacta’s entry to the third largest Asia-Pacific biotech market.
Friday, September 28, 2012
Avacta Analytical Partners with UCL
Avacta Analytical is partnering with University College London (UCL) as an industrial sponsor of the EPSRC Centre for Innovative Manufacturing in Emergent Macromolecular Therapies.
Friday, November 18, 2011
Scientific News
Microdroplet Reactors Mimic Living Systems
Researchers use microdroplets to study non-equilibrium reactions like those in living organisms.
NIH Researchers Identify Striking Genomic Signature for Cancer
Institute has identified striking signature shared by five types of cancer.
CRI Develops Innovative Approach for Identifying Lung Cancer
Institute has developed innovative approach for identifying processes that fuel tumor growth in lung cancer patients.
Envigo Rat Models Proven to be Susceptible to Intra-Vaginal HSV-2 Infection and Protectable
Scientific findings establish the effectiveness of new approach to investigate the protective effects of vaccine candidates and anti-viral microbodies and to study asymptomatic primary genital HSV-2 infection.
What do Banana Peels and Human Skin Have in Common?
Human skin and banana peels have something in common: they produce the same enzyme when attacked. By studying fruit, researchers have come up with an accurate method for diagnosing the stages of this form of skin cancer.
The Spice of Life
Scientists discover important genetic source of human diversity.
Cytoskeleton Crew
Findings confirm sugar's role in helping cancers survive by changing cellular architecture.
The Power of Three
Overlooked portion of cell “death receptor” critical in some cancers, autoimmune diseases.
Drug that Activates Innate Immune System Identified
Researchers from the institute have identified a drug, which is straightforward to synthesize and to couple to antigens that induce an immune response and may prove useful in the generation of vaccines.
Removing Race from Human Genetic Research
A group of scientists are urging their colleagues to take a step forward and stop using racial categories when researching and studying human genetics.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!