Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>News>This Article

Creabilis Receives Prestigious Technology Strategy Board Biomedical Catalyst Award

Published: Tuesday, November 06, 2012
Last Updated: Monday, November 05, 2012
Bookmark and Share
£1.42m funding will drive development of new treatment for Atopic Dermatitis.

Creabilis SA has announced that it has been granted a prestigious Biomedical Catalyst funding award, of £1.42m. Creabilis is one of the first companies to receive this award that will be used to advance the development of its clinical stage topical kinase inhibitor, CT327.

The £180 million Biomedical Catalyst is an integrated translational funding programme jointly operated by the Medical Research Council and the Technology Strategy Board providing responsive and effective support for the best life science opportunities arising in the UK.

It was announced by the Prime Minister David Cameron in December 2011 as part of the UK Government’s Life Sciences Strategy.

The award will be used by Creabilis in a £2.37m project to further develop CT327, a novel, first-in-class topical kinase inhibitor that is in clinical development to treat a number of dermatological diseases.

Specifically, the funding will be used to support a Phase IIb clinical study to further evaluate the safety and efficacy of CT327 in patients with Atopic Dermatitis.

Atopic Dermatitis (AD) is a poorly treated dermatological disorder, often described as an ‘itch with a rash’. The number of people with AD has increased more than three fold in the past 30 years, with over 1 million people affected in the UK alone.

It has a significant impact on patients’ and carers’ quality of life, the disease being particularly prevalent amongst children.

Although some older treatments exist, there is a significant need for new therapies that are safe for long term use and address all features of the disease, including itch.

CT327 has been developed using Creabilis’ Low Systemic Exposure (LSE) technology that creates ‘topical-by-design’ drugs optimized for high local and low systemic exposures.

Previously, in an international Phase IIa study, CT327 was effective in treating all aspects of AD and has proven safe and well tolerated in a further five clinical studies.

Dr Eliot Forster, CEO of Creabilis, said: “It is satisfying to have won this highly prestigious award and we are grateful to the Technology Strategy Board for their diligence. We firmly believe that CT327 will make a real difference to patients suffering from Atopic Dermatitis. The Biomedical Catalyst funding will enable us to complete this important study bringing CT327 one step closer to all patients suffering from this common and poorly treated disease.”

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More Than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Creabilis Announces Treatment of First Patients in its Phase 2b Trial of CT327
Phase 2b study of CT327 in patients with atopic dermatitis.
Monday, September 23, 2013
Creabilis Announces New Appointments to its Scientific Advisory Board
Appointment of Professor Gil Yosipovitch and Professor Praveen Anand to Company’s Board.
Monday, July 29, 2013
Creabilis Announces Headline Results of its Phase 2b Trial of CT327
Clinically and statistically significant reduction of chronic pruritus (itch) seen in psoriasis patients.
Friday, May 10, 2013
Creabilis Appoints Dr Simon Russell as Chief Business Officer
Dr Russell to maximize the commercial potential of Company’s products and technology.
Thursday, May 03, 2012
Creabilis Raises €15M ($20M) in Series B Fundraising Round
Funds to advance development of Creabilis’ first-in-class products.
Wednesday, October 05, 2011
Scientific News
High Throughput Mass Spectrometry-Based Screening Assay Trends
Dr John Comley provides an insight into HT MS-based screening with a focus on future user requirements and preferences.
Revolutionary Technologies Developed to Improve Outcomes for Lung Cancer Patients
Breath test to detect lung cancer brings oxygen directly to the wound.
NIH Supports New Studies to Find Alzheimer’s Biomarkers in Down Syndrome
Initiative will track dementia onset, progress in Down syndrome volunteers.
Promising Drug Combination for Advanced Prostate Cancer
A new drug combination may be effective in treating men with metastatic prostate cancer. Preliminary results of this new approach are encouraging and have led to an ongoing international study being conducted in 196 hospitals worldwide.
A Cellular Symphony Responsible for Autoimmune Disease
Broad Institute researchers have used a novel approach to increase our understanding of the immune system as a whole.
When it Comes to Breast Cancer, Common Pigeon is No Bird Brain
If pigeons went to medical school and specialized in pathology or radiology, they’d be pretty good at distinguishing digitized microscope slides and mammograms of normal vs. cancerous breast tissue, a new study has found.
Editing of LIMS Data Made Faster and More Efficient in Matrix Gemini
The latest version of the Matrix Gemini LIMS (Laboratory Information Management System) from Autoscribe Informatics now provides faster and more efficient editing of LIMS data by eliminating the need for a second editing screen.
University of Edinburgh, Selcia Achieve Key Milestones in Drug Development Program
Scientists from the University of Edinburgh, working with Selcia, have successfully passed the 20-month milestone targets of a 30-month Wellcome Trust SDDi £2.5 million project to design novel treatments for sleeping sickness.
Red Clover Genome to Help Restore Sustainable Farming
The Genome Analysis Centre (TGAC) in collaboration with IBERS, has sequenced and assembled the DNA of red clover to help breeders improve the beneficial traits of this important forage crop.
How a Genetic Locus Protects Adult Blood-Forming Stem Cells
Mammalian imprinted Gtl2 protects adult hematopoietic stem cells by restricting metabolic activity in the cells' mitochondria.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos