Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>News>This Article

Cartagenia and Interactive Biosoftware Integrate Technologies

Published: Wednesday, November 07, 2012
Last Updated: Wednesday, November 07, 2012
Bookmark and Share
Interactive Biosoftware’s Alamut gene browser capabilities, Cartagenia BENCHlab next-generation sequencing platform to be sold as integrated solution.

Cartagenia Inc. and Interactive Biosoftware LLC (IB) jointly announced today that they have entered into an agreement under which Cartagenia will integrate IB’s Alamut gene visualization software into its BENCHlab platform, a web-based software and database platform that interprets genomic variation in routine diagnostics. The combined solution merges the variant data, filtering, interpretation and management capabilities of the BENCHlab platform with the annotation and visualization capabilities of the Alamut software. Cartagenia and IB will each market the combined solution to their respective customers, while continuing to sell their own products independently.

André Blavier, CEO of Interactive Biosoftware, called the alliance between the companies a natural fit.
“This partnership with Cartagenia makes perfect sense,” Blavier said. “Next generation sequencing (NGS) is now migrating from elite academic centers for use clinically and commercially in laboratories and medical centers worldwide. To facilitate this broader use, the combination of our technologies is a natural and important step. Our Alamut solution is now extended with capabilities which were previously unavailable to us, such as patient database management, massively parallel variant filtering, and advanced lab reporting.”

Since early in 2012, a number of genetics labs have successfully set up their NGS diagnostics on the BENCHlab NGS platform with Alamut embedded in their workflow, and are pleased with the integrated experience, noted Herman Verrelst, CEO of Cartagenia. The high level of automation and the lab-validated variant filtration pipelines in BENCHlab are perfectly complemented by the Alamut gene browser that allows lab technicians to visualize specific variants of interest.

“After the launch of our BENCHlab NGS solution earlier this year, we have seen a strong adoption by existing customers as well as by new genetics labs that are rolling out next generation sequencing platforms in clinical diagnostics,” Verrelst said. “Many of these customers were already using the Alamut software for data interpretation and visualization. A technical integration of the two systems provides a single workflow experience. We now also have a commercial agreement with IB through which our customers can obtain the Alamut solution directly from us under a singe license agreement and under favorable commercial terms once they go to higher data and user volumes, which is anticipated with the introduction of NGS platforms.”

With the combined software, candidate variants are assessed in detail and then labeled as a clinical finding on the patient findings in BENCHlab, seamlessly tying in with its template based lab reporting system, and managed variant databases. Additionally, with BENCHlab, the lab gets access to clinical information that allows assessing variants in context of phenotype, and has the option to integrate findings and conclusions with a Lab Information Management system or the Electronic Health Record System at the lab or hospital.

Blavier added that IB will continue to focus on building the core Alamut product and provide the highest-quality product to the market, as IB has done in the past.

“We have recently extended the software with BAM file visualization features and introduced Alamut-HT, a high-throughput annotation engine for NGS- generated variant files,” Blavier said. “This software enriches raw NGS variants with multiple attributes including effects on human genes, single nucleotide polymorphisms information, and missense and splicing predictions. The latest version includes annotations from HGMD, the Human Gene Mutation Database, and from ESP, the NHLBI Exome Server Project.”

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More Than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Cartagenia Consortium Lungcadia Wins $1.76 M Grant
Cartagenia teams with BIOBASE and Hannover Medical School in Lungcadia project for cancer diagnostics and personalized therapy support.
Friday, November 07, 2014
ISCA Consortium Selects Cartagenia Software to Automate CNV Atlas Data Acquisition
Cartagenia has announced that it has signed an agreement with the International Standards for Cytogenomic Arrays (ISCA) Consortium to set up an automated data acquisition pipeline based on Cartagenia’s BENCH data management solution.
Thursday, December 16, 2010
Scientific News
High Throughput Mass Spectrometry-Based Screening Assay Trends
Dr John Comley provides an insight into HT MS-based screening with a focus on future user requirements and preferences.
How a Genetic Locus Protects Adult Blood-Forming Stem Cells
Mammalian imprinted Gtl2 protects adult hematopoietic stem cells by restricting metabolic activity in the cells' mitochondria.
Genetic Basis of Fatal Flu Side Effect Discovered
A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a recent study.
New Tech Vastly Improves CRISPR/Cas9 Accuracy
A new CRISPR/Cas9 technology developed by scientists at UMass Medical School is precise enough to surgically edit DNA at nearly any genomic location, while avoiding potentially harmful off-target changes typically seen in standard CRISPR gene editing techniques.
The MaxSignal Colistin ELISA Test Kit from Bioo Scientific
Kit can help prevent the antibiotic apocalypse by keeping last resort drugs out of the food supply.
"Good" Mozzie Virus Might Hold Key to Fighting Human Disease
Australian scientists have discovered a new virus carried by one of the country’s most common pest mosquitoes.
Non-Disease Proteins Kill Brain Cells
Scientists at the forefront of cutting-edge research into neurodegenerative diseases such as Alzheimer’s and Parkinson’s have shown that the mere presence of protein aggregates may be as important as their form and identity in inducing cell death in brain tissue.
Closing the Loop on an HIV Escape Mechanism
Research team finds that protein motions regulate virus infectivity.
New Class of RNA Tumor Suppressors Identified
Two short, “housekeeping” RNA molecules block cancer growth by binding to an important cancer-associated protein called KRAS. More than a quarter of all human cancers are missing these RNAs.
Potential Treatment for Life-Threatening Viral Infections Revealed
The findings point to new therapies for Dengue, West Nile and Ebola.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos