Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Cartagenia and Interactive Biosoftware Integrate Technologies

Published: Wednesday, November 07, 2012
Last Updated: Wednesday, November 07, 2012
Bookmark and Share
Interactive Biosoftware’s Alamut gene browser capabilities, Cartagenia BENCHlab next-generation sequencing platform to be sold as integrated solution.

Cartagenia Inc. and Interactive Biosoftware LLC (IB) jointly announced today that they have entered into an agreement under which Cartagenia will integrate IB’s Alamut gene visualization software into its BENCHlab platform, a web-based software and database platform that interprets genomic variation in routine diagnostics. The combined solution merges the variant data, filtering, interpretation and management capabilities of the BENCHlab platform with the annotation and visualization capabilities of the Alamut software. Cartagenia and IB will each market the combined solution to their respective customers, while continuing to sell their own products independently.

André Blavier, CEO of Interactive Biosoftware, called the alliance between the companies a natural fit.
“This partnership with Cartagenia makes perfect sense,” Blavier said. “Next generation sequencing (NGS) is now migrating from elite academic centers for use clinically and commercially in laboratories and medical centers worldwide. To facilitate this broader use, the combination of our technologies is a natural and important step. Our Alamut solution is now extended with capabilities which were previously unavailable to us, such as patient database management, massively parallel variant filtering, and advanced lab reporting.”

Since early in 2012, a number of genetics labs have successfully set up their NGS diagnostics on the BENCHlab NGS platform with Alamut embedded in their workflow, and are pleased with the integrated experience, noted Herman Verrelst, CEO of Cartagenia. The high level of automation and the lab-validated variant filtration pipelines in BENCHlab are perfectly complemented by the Alamut gene browser that allows lab technicians to visualize specific variants of interest.

“After the launch of our BENCHlab NGS solution earlier this year, we have seen a strong adoption by existing customers as well as by new genetics labs that are rolling out next generation sequencing platforms in clinical diagnostics,” Verrelst said. “Many of these customers were already using the Alamut software for data interpretation and visualization. A technical integration of the two systems provides a single workflow experience. We now also have a commercial agreement with IB through which our customers can obtain the Alamut solution directly from us under a singe license agreement and under favorable commercial terms once they go to higher data and user volumes, which is anticipated with the introduction of NGS platforms.”

With the combined software, candidate variants are assessed in detail and then labeled as a clinical finding on the patient findings in BENCHlab, seamlessly tying in with its template based lab reporting system, and managed variant databases. Additionally, with BENCHlab, the lab gets access to clinical information that allows assessing variants in context of phenotype, and has the option to integrate findings and conclusions with a Lab Information Management system or the Electronic Health Record System at the lab or hospital.

Blavier added that IB will continue to focus on building the core Alamut product and provide the highest-quality product to the market, as IB has done in the past.

“We have recently extended the software with BAM file visualization features and introduced Alamut-HT, a high-throughput annotation engine for NGS- generated variant files,” Blavier said. “This software enriches raw NGS variants with multiple attributes including effects on human genes, single nucleotide polymorphisms information, and missense and splicing predictions. The latest version includes annotations from HGMD, the Human Gene Mutation Database, and from ESP, the NHLBI Exome Server Project.”


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More Than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Cartagenia Consortium Lungcadia Wins $1.76 M Grant
Cartagenia teams with BIOBASE and Hannover Medical School in Lungcadia project for cancer diagnostics and personalized therapy support.
Friday, November 07, 2014
ISCA Consortium Selects Cartagenia Software to Automate CNV Atlas Data Acquisition
Cartagenia has announced that it has signed an agreement with the International Standards for Cytogenomic Arrays (ISCA) Consortium to set up an automated data acquisition pipeline based on Cartagenia’s BENCH data management solution.
Thursday, December 16, 2010
Scientific News
Sorting Through Cellular Statistics
Aaron Dinner, professor in chemistry, and his graduate student Herman Gudjonson are trying to read the manual of life, DNA, as part of the Dinner group’s research into bioinformatics—the application of statistics to biological research.
Playing 'Tag' with Pollution lets Scientists See Who's It
Using a climate model that can tag sources of soot from different global regions and can track where it lands on the Tibetan Plateau, researchers have determined which areas around the plateau contribute the most soot — and where.
Women’s Immune System Genes Operate Differently from Men’s
A new technology reveals that immune system genes switch on and off differently in women and men, and the source of that variation is not primarily in the DNA.
Long Telomeres Associated with Increased Lung Cancer Risk
Genetic predisposition for long telomeres predicts increased lung adenocarcinoma risk.
First Artificial Ribosome Designed
Researchers at the University of Illinois at Chicago and Northwestern University have engineered a tethered ribosome that works nearly as well as the authentic cellular component, or organelle, that produces all the proteins and enzymes within the cell.
High-Resolution 3D Images Reveal the Muscle Mitochondrial Power Grid
NIH mouse study overturns scientific ideas on energy distribution in muscle.
Expanding the Brain
A team of researchers has identified more than 40 new “imprinted” genes, in which either the maternal or paternal copy of a gene is expressed while the other is silenced.
Identifying a Key Growth Factor in Cell Proliferation
Researchers discover that aspartate is a limiter of cell proliferation.
The Genetic Roots of Adolescent Scoliosis
Scientists at the RIKEN Center for Integrative Medical Sciences in collaboration with Keio University in Japan have discovered a gene that is linked to susceptibility of Scoliosis.
A Gene-Sequence Swap Using CRISPR to Cure Haemophilia
For the first time chromosomal defects responsible for hemophilia have been corrected in patient-specific iPSCs using CRISPR-Cas9 nucleases
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!