Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

NIH Awards New England Biolabs Grant for the Research and Development of Novel Enzymes for Epigenetic Studies

Published: Friday, November 09, 2012
Last Updated: Friday, November 09, 2012
Bookmark and Share
New England Biolabs (NEB) has recently received a $640,000 Phase II Small Business Innovation Research (SBIR) grant to expand its research and product development of novel enzymatic tools for epigenetic analysis.

This latest grant adds to the more than $1.1 million of SBIR funds awarded for this research since 2009.

Since its establishment in 1974, NEB has been dedicated to the discovery and development of reagents for the life sciences industry. A key to this effort has been the focused development of recombinant enzyme technology by NEB scientists, resulting in  a wide array of enhanced tools for molecular biology research and analysis, such as engineered restriction enzymes with greater specificity under a wider range of reaction conditions. This commitment has placed NEB at the forefront of restriction enzyme research and supply.

The use of restriction enzymes in epigenetic studies has been a research focus at NEB for many years. Specifically, research in the area of methylation-dependent and methylation-sensitive restriction enzymes has led to the discovery and commercialization of new tools to identify these DNA modifications. For example, in 2010, NEB scientists identified the MspJI family of restriction enzymes, which has the ability to excise small fragments of methylated DNA for use in epigenetics studies. This latest SBIR grant award enables further research in this area, and ultimately a deeper understanding of epigenetic marks in the mammalian genome.

"Since its founding, NEB has coupled its basic research with the development of new tools for molecular biology," states Dr. Bill Jack, Director of Research at NEB. "The repository of knowledge, generated during the almost four decades of restriction endonuclease study at NEB, has fueled a discovery program that has radically expanded the utility of restriction endonucleases and activity on a variety of DNA templates, including those created by epigenetic modification. We are committed to continuing this discovery process, and to use these novel new enzyme.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More Than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

New England Biolabs® Announces Plans for GMP manufacturing
Responds to customer needs for reagents use in in vitro diagnostics applications.
Friday, June 12, 2015
Protocols.io, New England Biolabs Partner
The aim of this collaboration is to improve experimental method sharing and communication amongst scientists.
Thursday, May 21, 2015
New England Biolabs® and Directed Genomics Partner
Partnership aims to develop novel target enrichment technologies for Next Generation Sequencing.
Monday, October 20, 2014
New England Biolabs®, Directed Genomics Partnership
Partnership established to develop novel target enrichment technologies for next generation sequencing.
Monday, October 20, 2014
Population Genetics Assigns NGS Patent to NEB
PGT assigns asymmetric adaptor library construction patent to New England Biolabs.
Tuesday, August 06, 2013
New England Biolabs Introduces NEBNext® Oligo Modules
Modules enable the construction of singleplex or multiplex high yield libraries for DNA, ChIP-Seq or mRNA sequencing on Illumina® instruments. NEBNext Oligo Modules contain a novel adaptor that ligates efficiently to end-repaired, dA-tailed DNA.
Tuesday, February 21, 2012
Scientific News
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.
One Step Closer to Precision Medicine for Chronic Lung Disease Sufferers
A study led by University of North Carolina at Chapel Hill, and National Jewish Health, has provided evidence of links between SNPs and known COPD blood protein biomarkers.
Gene Regulation in Brain May Explain Repetitive Behaviors in Rett Syndrome Patients
The research could be a key step in developing treatments to eliminate symptoms that drastically impair the quality of life in Rett patients.
Heart Arrhythmia Caused by Mosaic of Mutant Cells
Researchers have solved the genetic mystery of an infant suffering from heart arrhythmia.
Iron Nanoparticles Make Immune Cells Attack Cancer
Researchers accidentally discover that nanoparticles invented for anemia treatment can trigger the immune system’s ability to destroy tumor cells.
Crispr Toolbox Expanded By Protein
Researchers have shown a newly discovered CRISPR protein has two distinct RNA cutting activities.
CES Score May Predict Response to Cancer Treatment
Researchers identify new type of biomarker that helps predict prognosis and response to several types of cancer treatment.
Uncovering Cancer’s ‘Invisibility Cloak’
Researchers discover cancer cell mechanism to become invisible to the body's immune system.
Genetic Impact of Endurance Training
Research has found that endurance training changes genetic activity in thousands of genes, giving rise to large number of altered RNA variants.
Treating Sepsis with Marine Mitochondria
Mitochondrial alternative oxidase from a marine animal combats bacterial sepsis.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!