Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>News>This Article

Study Explains how Bread Consumption can Improve Cardiovascular Health

Published: Friday, November 30, 2012
Last Updated: Friday, November 30, 2012
Bookmark and Share
Researchers identify metabolic factors related to bread's beneficial effects on cardiovascular health.

The study has been led by the professor Rafael Llorach, Ramon y Cajal researcher from the Department of Nutrition and Bromatology at the Faculty of Pharmacy and from the Food and Nutrition Torribera campus of the UB. This new research identified the metabolic factors which are possibly related to bread’s beneficial effects on lipid profile, and on the cardiovascular health of its consumers.
 The work, which is part of the Functional Foods Consolider-Ingenio Project and is promoted by the initiative Pan Cada Día, use techniques of metabolomics in order to analyse the impact of bread consumption (white and wholemeal) in a population sample made up of 275 advanced years volunteers who are in high cardiovascular and are take part in the study PREDIMED.

According to the professor Rafael Llorach, “the data obtained in the study indicate that daily bread consumption, especially wholemeal one, as an element of a balanced diet, is associated to a healthier lipid profile that shows lower insulin blood concentrations”. In the opinion of the professor Cristina Andrés-Lacueva, co-director of the project and head of the Research Group on Biomarkers and Nutritional and Food Metabolomics, “the metabolomics study drove us to identify the potential metabolic factors hid behind the positive effects that bread consumption has on the lipid profile and which can be determinant to be in a better cardiovascular health”. To be precise, the authors of the study identified a metabolite related to PPAR-alfa activity (a nuclear receptor involved in lipid metabolism which is raised in wholemeal bread consumers).

A healthier lipid profile

The study points out that people who daily consumes bread, white or wholemeal, show a healthier lipid profile —lower levels of LDL cholesterol and higher levels of HDL cholesterol— than the people who consume it sporadically or don’t consume it. The study also reveals that regular bread consumption is associated with a lower insulin concentration. “This is a really important data, when the body does not answer in a correct way to the insulin’s action, glucose cannot reach the inner part of cells and it is accumulated in blood”, explains Andrés-Lacueva. This mechanism —insulin resistance— is a key pathological process in the development of type 2 diabetes mellitus, also associated with a high risk of cardiovascular disease.

The results of the study coincide with other scientific works that also talk about a possible prevention effect of fibre consumption —especially the wholemeal ones— against the development of insulin resistance. Moreover, this study shows the regular consumption of bread, a good source of carbohydrates, vitamins, minerals and fibre, what represents an increase in the consumption of carbohydrates is not related to an increase of body weight.

Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More Than 5,200+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
Integrated Omics Analysis
Studying multi-omics promises to give a more holistic picture of the organism and its place in its ecosystem, however despite the complexities involved those within the field are optimistic.
Unravelling the Role of Key Genes and DNA Methylation in Blood Cell Malignancies
Researchers from the University of Nebraska Medical Center have demonstrated the role of Dnmt3a in safeguarding normal haematopoiesis.
Salford Lung Study - The First Real World Clinical Trial
In this podcast, we learn about the Salford Lung Study and its potential to revolutionize the way we assess new drugs and treatments around the world.
Point of Care Diagnostics - A Cautious Revolution
Advances in molecular biology, coupled with the miniaturization and improved sensitivity of assays and devices in general, have enabled a new wave of point-of-care (POC) or “bedside” diagnostics.
Gene Therapy Going Global with Portable Device
Portable 'gene therapy in a box' could make future cancer and HIV cures affordable in developing countries.
Preventing "Friendly Fire" in the Pancreas
Researchers inhibit process that leads to the body attacking its own insulin-producing cells.
3D-Printed Heart-On-A-Chip with Integrated Sensors
Researchers have created the first 3D-printed organ-on-a-chip with integrated sensors, paving the way for more complex, customizable devices.
Wrapping up the Genome
Researchers successfully package complete yeast genome using purified components, yielding new insights into genome mechanisms.
Drug Target for Triple-Negative Breast Cancer Found
A team of researchers led by UC San Francisco scientists has identified a new drug target for triple-negative breast cancer.
Precision Medicine Guiding Cancer Patients’ Chemotherapy Decision
New study finds doctors use genetic test to measure breast cancer recurrence risk, make tailored treatment recommendations.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,200+ scientific videos