Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Two UT Southwestern Scientists Honored as Rising Stars in Texas Research

Published: Thursday, December 13, 2012
Last Updated: Wednesday, December 12, 2012
Bookmark and Share
Dr. Lora Hooper and Dr. Youxing Jiang are among the four chosen for the 2013 Edith and Peter O’Donnell Awards.

The Academy of Medicine, Engineering, and Science of Texas (TAMEST) has announced that two UT Southwestern Medical Center researchers are among the four chosen for the 2013 Edith and Peter O’Donnell Awards.

Dr. Lora Hooper, associate professor of immunology and microbiology, and Dr. Youxing Jiang, professor of physiology, will be honored at a banquet at the Westin Galleria in Dallas on Jan. 17 in conjunction with TAMEST’s 10th annual conference.

Both are accomplished Howard Hughes Medical Institute investigators, and Dr. Hooper also has an appointment in UT Southwestern’s Cancer Immunobiology Center.

Each year, the awards honor outstanding achievements by early-career investigators in science, medicine, engineering, and technology innovation. Each award consists of a $25,000 honorarium, a citation, a trophy, and an invitation to speak at the conference.

The 2013 O’Donnell Award in Medicine honors Dr. Hooper for her discovery of immune mechanisms that promote host-bacterial interactions.

These discoveries in part explain how beneficial bacteria can safely exist in the intestinal tract and may ultimately reveal what to do when illness-causing bacteria predominate.

The 2013 O’Donnell Award in Science recognizes Dr. Jiang’s efforts to elucidate the atomic structures of membrane-bound ion channels, which are cell surface proteins that allow specific charged particles like sodium and potassium ions to pass through or be blocked by cell membranes.

“The achievements of Dr. Hooper and Dr. Jiang exemplify the breadth of research under way at UT Southwestern, important work with benefits we hope will extend across the state of Texas and throughout the world of medical science,” said Dr. Daniel K. Podolsky, president of UT Southwestern.

Dr. Podolsky continued, “We are grateful to Edith and Peter O’Donnell for their support of scientific advancement.”

Ion channels are so fundamental to human existence that problems in these proteins are blamed for a range of conditions called channelopathies, which include some forms of epilepsy, migraine, fibromyalgia and paralysis.

Solving the atomic structure of ion channels, a very high-tech way of visualizing them at the atomic level, is a major step toward understanding and better treating these conditions, Dr. Jiang explained.

“I am deeply honored,” said Dr. Jiang. “This award recognizes the hard work of many outstanding scientists in my lab. I am also grateful for the incredible support that the physiology department and the university have provided to us.”

Much of Dr. Hooper’s research focuses on the battles that take place, or don’t, in a sort of “demilitarized zone” in the intestine. That zone is a 50-micron-wide area - about half the width of a human hair - between the intestinal wall and the normally good, or commensal, bacteria that live in the gut.

Under normal conditions, these bacteria aid in digestion and the delivery of nutrients from the food we eat without damaging the delicate intestinal lining. When something goes wrong with this arrangement the bacteria are able to invade the intestinal wall and can cause inflammatory bowel disorders.

“It is a tremendous honor to receive this award, which is a reflection of the contributions of many excellent students and colleagues that I've worked with in my lab, as well as the collaborative environment and standard of scientific excellence at UT Southwestern," Dr. Hooper said.

Last fall, Dr. Hooper published a study in the journal Science showing for the first time how a protein that her laboratory discovered in 2006 works to police the intestinal demilitarized zone and keep bacteria from damaging the intestinal lining.

Most recently, in a study published in the Proceedings of the National Academy of Sciences in October, her laboratory found that gut bacteria launch biological warfare against other bacterial species in response to environmental stress, such as changes in available nutrients or the presence of antibiotics.

The bacteria go to war by churning out viruses that attack other bacterial species. The scientists hope to harness this intestinal warfare to develop ways to fight antibiotic-resistant bacterial infections.

Other 2013 O’Donnell Award winners are Dr. Li Shi of UT-Austin for engineering and Dr. Timothy Nedwed of ExxonMobil Upstream Research Company for technology innovation.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,100+ scientific posters on ePosters
  • More Than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

New $17 Million Cryo-Electron Microscope Center Provides Extraordinary Views
Institute has announced opening of a new $17 million cryo-EM facility housing a unique collection of instruments that researchers can use to view 3-D images of objects.
Thursday, May 12, 2016
New Autism Blood Biomarker Identified
Researchers at UT Southwestern Medical Center have identified a blood biomarker that may aid in earlier diagnosis of children with autism spectrum disorder, or ASD.
Friday, May 06, 2016
Enzyme Link Between Excessive Heart Muscle Growth, Cancer Growth
Researchers at UTSW have found that the drugs currently used to inhibit these enzymes in cancer may also be effective in treating enlargement of the heart muscle.
Saturday, April 16, 2016
Treatment of Common Prostate Cancer
Researchers at UTSW have found that the prostate cancer treatments suppress immune response and may promote relapse.
Friday, April 08, 2016
A Metabolic Twist that Drives Cancer Survival
A novel metabolic pathway that helps cancer cells thrive in conditions that are lethal to normal cells has been identified.
Friday, April 08, 2016
Novel Metabolic Twist that Drives Cancer Survival
Researchers at CRI at UT Southwestern have identified a novel metabolic pathway that helps cancer cells thrive in conditions that are lethal to normal cells.
Thursday, April 07, 2016
Structure of Crucial Enzyme Identified
Researchers at UTSW have determined the atomic structure of an enzyme that plays an essential role in cell division and better treatment of cancer.
Thursday, March 31, 2016
Mutation That Causes Rare Disease
A mutation has been discovered that causes a rare systemic disorder known as XLPDR and confirmed a role for nucleic acids in immune function.
Tuesday, March 29, 2016
Promoting Liver Tissue Regeneration
Researchers at CRI have reported that inactivating a certain protein-coding gene promotes liver tissue regeneration in mammals.
Saturday, March 26, 2016
Lupus Study Shows Precision Medicine’s Potential to Define the Genetics of Autoimmune Disease
Researchers at UT Southwestern have used next-generation DNA sequencing technology to identify more than 1,000 gene variants that affect susceptibility to SLE.
Saturday, March 19, 2016
Researchers Find New Cytoplasmic Role
Researchers at UT Southwestern Medical Center have found new cytoplasmic role for proteins linked to neurological diseases, cancers.
Friday, March 18, 2016
Researchers’ Work Shines LIGHT on how to Improve Cancer Immunotherapy
Researchers at UT Southwestern Medical Center have reported a strategy to make a major advancement in cancer treatment.
Thursday, March 17, 2016
UTSW Researchers Build Powerful 3-D Microscope, Create Images Of Cancer Cells
Researchers at UTSW have designed a microscope capable of creating high-resolution, 3-D images of living cancer cells in realistic and controlled microenvironments.
Friday, February 26, 2016
Pcsk9-Inhibitor Drug Class That Grew out of UTSW Research Becomes a Game-Changer for Patient
Researchers at UTSW have developed a new pcsk9-inhibitor drug class that effective in reduced the high cholesterol level.
Friday, February 26, 2016
CRI Develops Innovative Approach for Identifying Lung Cancer
Institute has developed innovative approach for identifying processes that fuel tumor growth in lung cancer patients.
Tuesday, February 09, 2016
Scientific News
The Rise of 3D Cell Culture and in vitro Model Systems for Drug Discovery and Toxicology
An overview of the current technology and the challenges and benefits over 2D cell culture models plus some of the latest advances relating to human health research.
Grant Supports Project To Develop Simple Test To Screen For Cervical Cancer
UCLA Engineering announces funding from Bill and Melinda Gates Foundation.
Injecting New Life into Old Antibiotics
A new fully synthetic way to make a class of antibiotics called macrolides from simple building blocks is set to open up a new front in the fight against antimicrobial drug resistance.
Insight into Bacterial Resilience and Antibiotic Targets
Variant of CRISPR technology paired with computerized imaging reveals essential gene networks in bacteria.
Advancing Protein Visualization
Cryo-EM methods can determine structures of small proteins bound to potential drug candidates.
Alzheimer’s Protein Serves as Natural Antibiotic
Alzheimer's-associated amyloid plaques may be part of natural process to trap microbes, findings suggest new therapeutic strategies.
Slime Mold Reveals Clues to Immune Cells’ Directional Abilities
Study from UC San Diego identifies a protein involved in the directional ability of a slime mold.
How Do You Kill A Malaria Parasite?
Drexel University scientists have discovered an unusual mechanism for how two new antimalarial drugs operate: They give the parasite’s skin a boost in cholesterol, making it unable to traverse the narrow labyrinths of the human bloodstream. The drugs also seem to trick the parasite into reproducing prematurely.
Illuminating Hidden Gene Regulators
New super-resolution technique visualizes important role of short-lived enzyme clusters.
Supressing Intenstinal Analphylaxis in Peanut Allergy
Study from National Jewish Health shows that blockade of histamine receptors suppresses intestinal anaphylaxis in peanut allergy.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,100+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!