Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

CYTOO’s 2D+ Technology and Institut Curie’s Organelle Map in the limelight at SLAS 2013

Published: Monday, January 07, 2013
Last Updated: Monday, January 07, 2013
Bookmark and Share
CYTOO will attend the Society for Laboratory Automation and Screening (SLAS) 2013 conference on 12-16 Jan, in Orlando, Florida, USA.

The company will present their 2D+ Solutions, opening fresh perspectives for cell based assay development in drug discovery.

2D+ Solutions are based on CYTOO’s standard and custom adhesive micropatterns in 96-well plates which guide cell architecture and behavior. By defining the 2D topology of cell adhesion, the 2D+ Cell Culture Platform enables fine control of the spreading and 3D shape of cultured cells in single- or multi-cellular configurations. This approach results in control of cell contractility, cell polarity, organelle positioning, and cell division axis.

2D+ Custom Solutions are specifically designed to bring expertise, resources and technology to address current bottlenecks in cell based assay development and screening in drug discovery.

2D+ Custom Solutions include: Exploratory solutions to guide customers through the initial exploration of the 2D+ technology with experienced PhD-level expert support; Assay development to select the best ecosystem for the requested cells; Screening to run pilot or full sized screens. All Solutions are tailored to the customer’s needs and can be carried out in the customer’s facilities or outsourced to CYTOO, on our fully equipped HCS screening platform.

The 2D+ technology addresses a major concern with traditional 2D culture, in which cells spread and move in an uncontrolled manner, introducing a considerable but unnoticed variability in cell function. Kristine Schauer, from the Institut Curie in Paris, France, used the crossbow adhesive micropatterns to get reproducible shape and distribution of intracellular compartments and developed a mathematical algorithm to generate and compare probabilistic density maps of the different endosome compartments.

This innovative approach is a powerful universal method to identify statistically relevant hits and drug effects in complex cell based assays, and according to Michel Bornens, COO at CYTOO “the method has now the potential to become a gold-standard in the quantitative analysis of cell-based high-throughput data”. Kristine Schauer’s Organelle Map figures among the nine 2013 SLAS Innovation Award finalists. A $10,000 cash prize will be attributed during SLAS 2013, and recognizes extraordinary achievement in innovative laboratory science and technology.

Attendees are invited to visit booth #310 to discuss their application with François Chatelain, President and CEO, and Lisa Minor, Application Development Leader.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More Than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
RNAi Screening Trends
Understand current trends and learn which application areas are expected to gain in popularity over the next few years.
New Weapon in the Fight Against Blood Cancer
This strategy, which uses patients’ own immune cells, genetically engineered to target tumors, has shown significant success against multiple myeloma, a cancer of the plasma cells that is largely incurable.
TOPLESS Plants Provide Clues to Human Molecular Interactions
Scientists at Van Andel Research Institute have revealed an important molecular mechanism in plants that has significant similarities to certain signaling mechanisms in humans, which are closely linked to early embryonic development and to diseases such as cancer.
Toxin from Salmonid Fish has Potential to Treat Cancer
Researchers from the University of Freiburg decode molecular mechanism of fish pathogen.
Study Finds Non-Genetic Cancer Mechanism
Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found.
Scientists Create CRISPR/Cas9 Knock-In Mutations in Human T Cells
In a project spearheaded by investigators at UC San Francisco, scientists have devised a new strategy to precisely modify human T cells using the genome-editing system known as CRISPR/Cas9.
Researchers Find U.S. Breast Milk is Glyphosate Free
Washington State University scientists have found that glyphosate, the main ingredient in the herbicide Roundup, does not accumulate in mother’s breast milk.
Peering into the Vapors
Research suggests that e-cigarettes are much less harmful than previous studies have indicated.
New Technique for Mining Health-conferring Soy Compounds
A new procedure devised by U.S. Department of Agriculture (USDA) scientists to extract lunasin from soybean seeds could expedite further studies of this peptide for its cancer-fighting potential and other health benefits.
Long-sought Discovery Fills in Missing Details of Cell 'Switchboard'
A biomedical breakthrough reveals never-before-seen details of the human body’s cellular switchboard that regulates sensory and hormonal responses.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!