Rigaku Corporation has introduced the new BioSAXS-1000 AUTO, a leap forward for experimental biological SAXS (small angle X-ray scattering) workflow for the home lab.
The BioSAXS-1000 AUTO combines Rigaku’s proven BioSAXS-1000 system with automatic sample handling, automatic data collection and automatic data analysis for biological solution scattering experiments.
Integral to the new BioSAXS-1000 AUTO is a state of the art SAXS analysis pipeline, called AAP (automatic analysis pipeline), that utilizes automated modules from the world’s most popular and comprehensive ATSAS program suite.
Resulting from collaboration between Rigaku and EMBL scientists in Hamburg, Germany, the automatic ATSAS-based pipeline inherent to AAP automates data processing steps such as profile averaging and buffer subtraction as well as data analysis steps such as Guinier and Porod analyses, P(r) calculation, ab initio shape determination and evaluation.
The end result of AAP is a summary of results for several concentrations of users protein solution, presented in an easy-to-review format with hyperlinks to visualize the data and models.
With the BioSAXS-1000 and AAP, Rigaku gives users all the tools they need to perform successful SAXS experiments in the home lab and to make the information obtained from SAXS an integral part of their research flow.