Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Thermo Scientific Extends UHPLC Performance to Biopharmaceutical Workflows

Published: Friday, March 22, 2013
Last Updated: Thursday, March 21, 2013
Bookmark and Share
Thermo Scientific Dionex UltiMate 3000 BioRS chromatography system combines corrosion resistance and UHPLC capability for bioseparations.

Thermo Fisher Scientific Inc. has announced that it will feature its Thermo Scientific Dionex UltiMate 3000 Biocompatible Rapid Separation (BioRS) liquid chromatography system during Pittcon 2013.

This system is designed to combine the performance advantages of ultrahigh-performance liquid chromatography (UHPLC) with the corrosion resistant flow path demanded by the analysis of proteins, peptides, nucleic acids and biotherapeutics.

Thermo Fisher will showcase the new system within booth 1835 during Pittcon 2013, being held in Philadelphia from March 17-21, 2013.

“We’ve designed this system to accelerate research into promising biotherapies, such as monoclonal antibody variants, and also to support biopharmaceutical research and QA/QC, including glycan analysis,” said Wulff Niedner, director, HPLC product marketing, for Thermo Fisher Scientific.

Niedner continued, “There is strong demand for a true high-performance biological separation platform, offering capabilities beyond reverse phase UHPLC. This combination of state-of-the-art technology and low-dispersion flow path is engineered to provide the high-peak capacity and sensitivity needed to analyze complex biomolecules.”

The system was developed for reliability and durability, even with harsh solvents used for many bioseparations.

The flow path is built of corrosion-resistant materials, enhancing robustness and extending the life of biocolumns, even under high salt or extreme pH conditions.

In addition, the materials used are designed to significantly reduce the risk of analytes interacting with internal surfaces of the flow path, protecting data quality.

The UltiMate 3000 BioRS system is powered by UltiMate 3000 Rapid Separation technology to support the high pressures required to separate many bioanalytes on high resolution UHPLC columns.

The system is engineered to operate at pressures as high as 1,000 bar (15,000 psi) and flow rates up to 8 mL/min. This wide flow/pressure footprint supports many biomolecule characterizations, including development, identification and quality control.

The tool-free biocompatible Thermo Scientific Dionex Viper fingertight fitting system is designed to facilitate connections without dead volume to combat peak-broadening effects.

The modular system offers many configuration options to accommodate most large molecule workflows. These include binary, quaternary and dual gradient mobile phase delivery, as well as parallel and tandem LC configurations.

Columns designed to optimize system performance
Thermo Fisher Scientific also chose Pittcon 2013 to introduce columns developed specifically to complement the performance of the UltiMate 3000 BioRS system.

The Thermo Scientific MAbPac SCX-10 RS column is designed for UHPLC separations of monoclonal antibodies. The Thermo Scientific DNAPac PA200 RS column can be used to analyze single nucleic acids and isomers to yield important structural information.

Both feature PEEK linings, providing highly inert flow paths designed to remain stable at UHPLC pressures, and ultra-stable packed beds designed for excellent retention reproducibility and long life.

Another biocolumn choice is the new Thermo Scientific Dionex GlycanPac AXH-1 column, designed to enhance glycan analysis with simultaneous charge, size and polarity HPLC separations.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More Than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Thermo Launches Geneticon
Thermo Fisher Scientific launches GenetiCon, a virtual resource showcasing the real-life science behind superheroic powers and more.
Tuesday, July 07, 2015
Thermo Fisher Agrees to Buy Alfa Aesar for $403M
The company announced a definitive agreement to buy the research chemical manufacturer for $403 million.
Friday, June 26, 2015
Ebola Sequencing Data Released to Global Research Community Online
To curb further spread of Ebola in Sierra Leone, a team of scientists that is part of an international, multi-organizational effort has released their first dataset of the virus’ genetic structure online.
Wednesday, June 03, 2015
Thermo's NGS Platform Selected for Nationwide Clinical Research Program
National Cancer Institute-MATCH trial to sequence thousands of tumor samples using Ion Torrent targeted sequencing technology.
Monday, June 01, 2015
Thermo Strengthens Bioprocessing Offering with Advanced Scientifics Acquisition
Thermo Fisher Scientific has acquired Advanced Scientifics, Inc., a global provider of single-use technologies for customized bioprocessing solutions, for $300 million in cash.
Friday, February 06, 2015
Thermo Fisher Q3 Revenues up 31 Percent
Thermo Fisher announced that revenues grew 31% to $4.17 billion for the third quarter ended September 27, 2014.
Thursday, October 23, 2014
Thermo Scientific Announces Listing of the Ion PGM Dx System
Company has completed the listing with the U.S. FDA as class II medical device.
Saturday, September 20, 2014
Thermo Fisher, NRLs Team to Confirm Dioxins in Feed and Food
Thermo Fisher Scientific worked closely with national reference labs (NRLs) in the European Union to support the development of new regulation.
Monday, September 08, 2014
Thermo Completes Sale of Cole-Parmer to GTCR
Thermo Fisher Scientific Inc. announced that it has completed the sale of its Cole-Parmer customer channel business to private equity firm GTCR LLC for approximately $480 million in cash.
Wednesday, August 20, 2014
Thermo Supports Distinguished Analytical Chemistry Seminar Series at NC State
An endowment established by the company provides opportunities to attend presentations by leading analytical chemistry authorities.
Tuesday, August 19, 2014
NSF International Expands Use of Thermo Scientific Watson LIMS
NSF International implements Thermo Scientific Watson LIMS to support bioanalytical testing for both clinical and non-clinical research studies at Bristol, CT laboratory.
Saturday, August 09, 2014
Thermo, NewLab Sign Forensic Sample Processing Distribution Agreement
Under the agreement, Thermo Fisher is the sole distributor and servicing agent of the CPA300™ and CPA200™ card processing instruments.
Friday, July 25, 2014
Thermo to Sell Cole-Parmer for $480M
Company has signed a definitive agreement to sell its Cole-Parmer channel business to private equity firm GTCR, LLC for $480 million in cash.
Monday, July 21, 2014
Reimagining UHPLC
To learn more about the new Vanquish UHPLC system from Thermo Fisher Scientific we spoke to Wulff Niedner, Director of HPLC Product Marketing.
Thursday, July 17, 2014
ATCC, CDC and Thermo Partner on Public Health RT-PCR Assay
New technology supports HIV-1 drug resistance surveillance in resource-limited countries.
Wednesday, June 25, 2014
Scientific News
RNAi Screening Trends
Understand current trends and learn which application areas are expected to gain in popularity over the next few years.
Diagnostic Test Developed for Enterovirus D68
researchers at Washington University School of Medicine in St. Louis have developed a diagnostic test to quickly detect enterovirus D68 (EV-D68), a respiratory virus that caused unusually severe illness in children last year.
How a Kernel Got Naked and Corn Became King
Ten thousand years ago, a golden grain got naked, brought people together and grew to become one of the top agricultural commodities on the planet.
Sweet Revenge Against Superbugs
A special type of synthetic sugar could be the latest weapon in the fight against superbugs.
New Material Opens Possibilities for Super-Long-Acting Pills
A pH-responsive polymer gel could create swallow able devices, including capsules for ultra-long drug delivery.
How To Keep Your Rice Arsenic-Free
Researchers at Queen’s University Belfast have made a breakthrough in discovering how to lower worrying levels of arsenic in rice that is eaten all over the world.
New Tool For Investigating RNA Gone Awry
A new technology – called “Sticky-flares” – developed by nanomedicine experts at Northwestern University offers the first real-time method to track and observe the dynamics of RNA distribution as it is transported inside living cells.
Computer Model Could Explain how Simple Molecules Took First Step Toward Life
Two Brookhaven researchers developed theoretical model to explain the origins of self-replicating molecules.
New Tech Enables Epigenomic Analysis with a Mere 100 Cells
A new technology that will dramatically enhance investigations of epigenomes, the machinery that turns on and off genes and a very prominent field of study in diseases such as stem cell differentiation, inflammation and cancer has been developed by researchers at Virginia Tech.
Access Denied: Leukemia Thwarted by Cutting Off Link to Environmental Support
A new study reveals a protein’s critical – and previously unknown -- role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!