Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>News>This Article

New Cyanine Dyes Reduce Time and Cost of Oligo Labelling

Published: Monday, March 25, 2013
Last Updated: Sunday, March 24, 2013
Bookmark and Share
Link Technologies’ solid-supported Cyanine 540 and 650 dyes increase workflow efficiency.

Link Technologies Ltd has launched a range of high quality cyanine dye products to support the continued increase in demand for fluorescent labelling in biological imaging and molecular diagnostics.

As well as introducing a new range of 3’-CPG solid supports modified with Cyanine 540 and Cyanine 650, Link Technologies now also manufactures and supplies the commonly used phosphoramidites, so researchers can now source an extended range of cyanine reagents produced to Link Technologies’ exacting standards.

Until now, 3’-cyanine modification of an oligonucleotide could only be done post-synthetically, normally to an amino-modified oligo, or by the use of a cyanine phosphoramidite onto a universal or modified support that will not interfere with the intended use of the oligo.

With Link Technologies’ innovative 3’-modified 1000Å CPG supports, customers can add cyanine dyes directly to their oligos of interest without any additional modification step.

Link Technologies’ cyanine dye supports therefore save time by reducing the number of experimental steps and avoid the unnecessary cost of amino-modified oligos or the inconvenience of combining cyanine phosphoramidites and universal supports.

Used as fluorescent markers in oligonucleotide synthesis, dyes are central to numerous detection techniques, such as probes for monitoring real-time PCR, fluorescence in situ hybridization, SERRS-based DNA detection assays and FRET studies in general (e.g. DNA-protein interaction studies).

3’-Labelling is particularly useful in the latter where the FRET partner is incorporated either at the 5’-end or within the oligonucleotide sequence.

Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More Than 5,200+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

LINK Strengthens Presence in Switzerland
Link Technologies appoints Swiss company as first partner in Europe.
Tuesday, September 08, 2015
LINK Strengthens Presence in Switzerland with Distribution Agreement
Link Technologies appoints Swiss company Chemie Brunschwig AG as first partner in Europe.
Friday, September 04, 2015
LINK Strengthens Presence in Japan with New Distribution Agreements
Link Technologies appoints Cosmo Bio and Shigematsu to work alongside Gene Design.
Tuesday, June 30, 2015
LINK Strengthens Board with Appointment of Marc Lemaître
Lemaître to join Link Technologies Ltd. as non-executive Director.
Wednesday, February 25, 2015
New SAB Supports LINK’s Growing Range of Innovative Reagents
LINK creates SAB with Brian Sproat and Thomas Rupp as first two appointments.
Friday, January 16, 2015
LINK Appoints New CEO
LINK has appointed Dr David Ricketts as its new Chief Executive Officer.
Tuesday, September 30, 2014
Shining the Light on Oligonucleotide Labelling
Link Technologies’ new Product Guide is the ‘go-to’ resource for oligo chemistry.
Tuesday, July 23, 2013
Link Technologies Announces Expansion into the Far East with New Distributor
Zirench Technology signed as local distributor for the Chinese market.
Thursday, June 13, 2013
Further Success for Link Technologies in Asia
Japanese company GeneDesign joins growing list of distributors.
Tuesday, February 26, 2013
Link Technologies Announces Partnership with American International Chemical
AIC to distribute Link’s specialist oligonucleotide modifiers in North America.
Wednesday, May 23, 2012
Link Technologies Secures Exclusive License for Ultra Sensitive Diagnostic Probes
Deal marks the start of ongoing collaboration between Link and The University of Manchester.
Tuesday, December 01, 2009
Link Technologies Inks Exclusive License to Agilent Technologies’ TC RNA Monomers
Under the terms of the agreement Link will manufacture and sell the four RNA monomer phosphoramidite reagents for use in research.
Monday, May 18, 2009
PNA Monomers: A Licence to Deal
Link Technologies to manufacture and sell PNA Monomers following deal with PNA Inventor Group.
Friday, June 22, 2007
Scientific News
Integrated Omics Analysis
Studying multi-omics promises to give a more holistic picture of the organism and its place in its ecosystem, however despite the complexities involved those within the field are optimistic.
Unravelling the Role of Key Genes and DNA Methylation in Blood Cell Malignancies
Researchers from the University of Nebraska Medical Center have demonstrated the role of Dnmt3a in safeguarding normal haematopoiesis.
Salford Lung Study - The First Real World Clinical Trial
In this podcast, we learn about the Salford Lung Study and its potential to revolutionize the way we assess new drugs and treatments around the world.
Point of Care Diagnostics - A Cautious Revolution
Advances in molecular biology, coupled with the miniaturization and improved sensitivity of assays and devices in general, have enabled a new wave of point-of-care (POC) or “bedside” diagnostics.
MRSA Uses Decoys to Evade a Last-Resort Antibiotic
Researchers at Imperial College London have discovered that MRSA releases decoy molecules that allow them to escape being killed by the antibiotic.
Fighting Cancer with Immune Response
New treatment elicits two-pronged immune response that destroys tumors in mice.
Nanomedicine for Breast Cancer Treatment
Using nanoparticles measuring only billionths of a meter in size, doctors are able to deliver drug molecules directly to the affected tissue.
Preventing "Friendly Fire" in the Pancreas
Researchers inhibit process that leads to the body attacking its own insulin-producing cells.
RNA-Binding Proteins Role in ALS Revealed
Researchers describe how damage to RNA-binding protein contributes to ALS, isolating a possible therapeutic target.
Zika Virus Infection Alters Human and Viral RNA
Researchers have discovered that Zika infections results in human and viral genetic modification.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,200+ scientific videos