Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Groundbreaking Clinical Trial Research on Genetic Basis of Children’s Health

Published: Wednesday, April 10, 2013
Last Updated: Wednesday, April 10, 2013
Bookmark and Share
Translational Research Institute at Inova utilizing joint solution to support unique clinical study of infants and their genomic profile.

Inova Translational Medicine Institute, a not-for-profit research initiative bringing personalized medicine to the public, has chosen a joint solution by Medidata Solutions and Digital Infuzion to support a unique observational study involving the correlation between a child’s genetic profile, their development and their long-term health. Together, Medidata and Digital Infuzion will deliver a web-based portal and cloud technology for collecting patient data, reviewing study progress and providing subjects with access to surveys and study information.

In a unique combination of genomics and clinical research, Inova is studying 2,500 families to analyze and predict the relationship between genetics and childhood developmental issues. The study will follow the infants for the first 1,000 days, starting in utero, and identify any health and development issues. By comparing these with the genetic profile of each family (child, mother and father), Inova hopes to identify specific genomic information associated with the medical issues, ultimately leading to new treatment and prevention pathways.

•    “We needed not only a sophisticated research design, but also the appropriate technology in order to conduct this unique investigation of genetics and infant health,” said John Niederhuber, MD, Inova EVP, CEO of the Inova Translational Medicine Institute and former director of the National Cancer Institute. “The clinical technology from Medidata and Digital Infuzion, both companies with strong reputations for supporting life science research with innovation, will allow for the smooth collaboration of the research team as well as the full participation of the parents in this study.”

The joint solution will bring together Medidata Rave®—the industry-leading system for capturing, managing and reporting clinical research data—with Digital Infuzion’s N of 1™ Health Research Platform—a technology service that provides tools for physicians and other care team members to collect, monitor and report on data and medical knowledge related to observational research, chronic disease and patient outcomes. Through a computer single sign-on, researchers will enter data about subject health, monitor participants and track study progress. Participating parents will complete surveys every six months via the portal and will have access to study updates and a library of materials to guide them through the three-year trial. Researchers can also generate immediate ad hoc reports aggregating real-time data from multiple sources, including patient health data from Rave and surveys, and genomic sequencing stored in the Amazon Cloud.

•    “By combining clinical data with individual gene sequencing, Inova is truly pushing the boundaries of medical research to identify exciting new treatments and prevention pathways,” said Glen de Vries, president of Medidata Solutions. “We have continually evolved the Medidata platform and its integrations with forward-thinking partners, such as Digital Infuzion, to create the innovations that enable novel research like this.”

To support efficient study execution and insightful analysis, Inova required an intuitive system that made it easy for parents and site staff alike to enter patient observations and access study information, while also offering robust reporting that could generate dynamic, data-rich reports to enable insightful analysis.

•    “Digital Infuzion is dedicated to optimizing knowledge sharing in clinical development and improving the research experience to enhance patient health,” said Hemant Virkar, president of Digital Infuzion. “We’re truly excited to once again partner with Medidata and leverage our combined technologies in support of Inova’s visionary research.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More Than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Breakthrough Flu Vaccine Inhibited by Pre-existing Antibodies
Universal truths – how existing antibodies are sabotaging the most promising new human flu vaccines.
Researchers Develop Software That Could Facilitate Drug Development
AptaTRACE can identify aptamers, potentially speed drug advancement.
Gene Therapy for Metabolic Liver Diseases
Researchers have tested gene therapy in pigs from hereditary tyrosinemia type 1, with corrected liver cells being transplanted into the diseased liver.
Zika Vaccine Candidates Show Promise
Two experimental vaccines have shown promise against a major viral strain responsible for the Brazilian Zika outbreak.
New Medication Shows Promise Against Liver Fibrosis in Animal Studies
Liver fibrosis is a gradual scarring of the liver that puts people at risk for progressive liver disease and liver failure.
Raw Eggs Deemed Safe to Eat
A report published today by the Advisory Committee on the Microbiological Safety of Food (ACMSF) into egg safety has shown a major reduction in the risk from salmonella in UK eggs.
Monitoring TTX Toxin in Shellfish
In a number of small studies, mussels and oysters from the eastern and northern part of the Oosterschelde in Holland were found to contain tetrodotoxin (TTX).
Gene Terapy for Muscle Wasting Developed
New gene therapy could save millions of people suffering from muscle wasting disease.
NIH Begins Yellow Fever Vaccine Trial
NIH has initiated an early-stage clinical trial of a vaccine to protect against yellow fever.
Gene-Editing 'Toolbox' Targets Multiple Genes Simultaneously
Researchers have designed a system that modifies, or edits, multiple genes in a genome at once while minimising unintentional effects.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!