Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Program for Breakthrough Biomedical Research to Celebrate 15 Years

Published: Tuesday, May 21, 2013
Last Updated: Tuesday, May 21, 2013
Bookmark and Share
A program that fosters basic science projects of potentially high impact is celebrating 15 years of discovery at UC San Francisco.

Today, no other program in the world support scientists like the Program for Breakthrough Biomedical Research (PBBR).

A beacon for the most courageous among UCSF investigators, PBBR uses private philanthropy to fund only those ideas that challenge conventional wisdom and could never qualify for funding from increasingly conservative grant sources like the National Institutes of Health (NIH).

“This unique program dares our scientists to dig deeper, ask tougher questions, and invent novel approaches that defy the status quo,” says Keith Yamamoto, PhD, vice chancellor for research at UCSF who directs the PBBR.

The UCSF community is invited to join the scientists and supporters who have made PBBR's success possible at a special event from 3:30 to 5 p.m. in Genentech Hall on the UCSF Mission Bay campus on Thursday, May 23.

The event program, titled “Unconventional Wisdom: Advancing Scientific Discovery by Breaking the Rules,” will feature a conversation with panelists moderated by Michael Krasny, PhD, host of KQED Forum.

Panelists include:

•    Joseph DeRisi, PhD, professor, UCSF Department of Biochemistry and Biophysics Howard Hughes Medical Institute Investigator, 2004 MacArthur Fellow;
•    Susan Desmond-Hellmann, MD, MPH, UCSF Chancellor, Arthur and Toni Rembe Rock Distinguished Professor;
•    Alfred Gilman, MD, PhD, Regental Professor Emeritus, UT Southwestern Medical Center Nobel Prize in Physiology or Medicine, 1994;  and
•    Anita Sil, PhD, MD, associate professor, UCSF Department of Microbiology and Immunology Howard Hughes Medical Institute Early Career Scientist.

Supporting Innovative Basic Research at UCSF

Established by co-founders Herbert and Marion Sandler, the program formerly known as the Sandler Program in Basic Science, is currently in its 16th year. Investigators credit the program with engendering hundreds of millions of dollars in subsequent grant funding, and projects and their derivatives have resulted in hundreds of publications and dozens of patents.

Some of the notable scientists at UCSF who received this critical funding include Wendell Lim, PhD, a professor of cellular and molecular pharmacology. His lab’s PBBR grant enabled him to advance his research to the point where the NIH took notice. He has since received direct NIH funding for his efforts to engineer “smart cells” that are programmed to carry out novel therapeutic functions in cancer and regenerative medicine.

The PBBR also has opened doors for Allison Doupe, MD, PhD, whose pioneering and somewhat quirky research into songbird learning has revealed clues that may improve the understanding of human brain development and disorders such as autism, schizophrenia and Parkinson’s disease.

Doupe, a professor of psychiatry and physiology and a member of the Keck Center for Integrative Neuroscience at UCSF, has found that songbirds, like humans, have specialized areas of the brain devoted to learning. By altering the part of the brain known as the basal ganglia, Doupe and her colleagues effectively eliminated variability in the birds’ song, which in turn interfered with their ability to learn.

Since receiving her PBBR grant, Doupe has also obtained funding from the NIH, the National Alliance for Research on Schizophrenia and Depression (NARSAD), and the Research Network on Early Experience and Brain Development.

Longtime philanthropists Herbert and Marion Sandler established the Sandler Foundation in 1991. The foundation has contributed more than $100 million to UCSF, including to PBBR; the Sandler Asthma Basic Research Center, an investigative unit dedicated to basic discovery in asthma research; support for neurosciences facilities and groundbreaking research; and a research effort focused on third world parasitic diseases.

The event on May 23 will feature a video tribute to Marion Sandler, who passed away last year at her home in San Francisco. Closing remarks will be delivered by Herbert Sandler and Chancellor Desmond-Hellmann.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,100+ scientific posters on ePosters
  • More Than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Transcription Factor Isoforms Implicated in Colon Diseases
UC Riverside study explains how distribution of two forms of a transcription factor in the colon influence risk of disease.
Thursday, May 19, 2016
An E.coli Detector May be in Your Hands Soon
Hand-held device that can be used to detect a variety of pathogens—including foodborne pathogens like E. coli—at all stages in the food supply chain, from fields to restaurants may be available soon.
Monday, May 16, 2016
Fructose Alters Hundreds of Brain Genes
UCLA scientists report that diet rich in omega-3 fatty acids can reverse the damage.
Tuesday, April 26, 2016
Study Yields the Key to Effective Personalized Medicine
A team of UCLA bioengineers and surgeons has taken a major step toward making personalized medicine a reality.
Monday, April 11, 2016
Tracking RNA in Live Cells
Technique may open doors to new treatments for many conditions, from cancer to autism.
Friday, March 18, 2016
Cat Stem Cell Therapy Gives Humans Hope
By the time Bob the cat came to the UC Davis veterinary hospital, he had used up most of his nine lives.
Monday, February 08, 2016
Crowdfunding the Fight Against Cancer
From budding social causes to groundbreaking businesses to the next big band, crowdfunding has helped connect countless worthy projects with like-minded people willing to support their efforts, even in small ways. But could crowdfunding help fight cancer?
Monday, February 08, 2016
Toxic Pollutants Found in Fish Across the World's Oceans
Scripps researchers' analysis shows highly variable pollutant concentrations in fish meat.
Friday, January 29, 2016
Key Enzyme in Pierce’s Disease Grapevine Damage Uncovered
UC Davis plant scientists have identified an enzyme that appears to play a key role in the insect-transmitted bacterial infection of grapevines with Pierce’s disease, which annually costs California’s grape and wine industries more than $100 million.
Wednesday, January 13, 2016
Science Magazine Names CRISPR ‘Breakthrough of the Year’
In its year-end issue, the journal Science chose the CRISPR genome-editing technology invented at UC Berkeley 2015’s Breakthrough of the Year.
Monday, December 21, 2015
Genome Sequencing May Save California's Legendary Sugar Pine
The genome of California’s legendary sugar pine, which naturalist John Muir declared to be “king of the conifers” more than a century ago, has been sequenced by a research team led by UC Davis scientists.
Thursday, December 17, 2015
Cellular “ORACLs” to Aid Drug Discovery
New approach for finding therapeutics is inspired by face-recognition software.
Wednesday, December 16, 2015
New Virus Disovered, Linked To Hepatitis C
Study is first to reveal entire genetic makeup of human pegivirus 2.
Tuesday, December 15, 2015
CRISPR-Cas9 Helps Uncover Genetics of Exotic Organisms
A new study illustrates the ease with which CRISPR-Cas9 can knock out genes in exotic animals to learn how those genes control growth and development.
Friday, December 11, 2015
UC Davis Cracks the Walnut Genome
Scientists at the University of California, Davis, have for the first time sequenced the genome of a commercial walnut variety.
Friday, December 11, 2015
Scientific News
The Rise of 3D Cell Culture and in vitro Model Systems for Drug Discovery and Toxicology
An overview of the current technology and the challenges and benefits over 2D cell culture models plus some of the latest advances relating to human health research.
Grant Supports Project To Develop Simple Test To Screen For Cervical Cancer
UCLA Engineering announces funding from Bill and Melinda Gates Foundation.
Injecting New Life into Old Antibiotics
A new fully synthetic way to make a class of antibiotics called macrolides from simple building blocks is set to open up a new front in the fight against antimicrobial drug resistance.
Insight into Bacterial Resilience and Antibiotic Targets
Variant of CRISPR technology paired with computerized imaging reveals essential gene networks in bacteria.
Advancing Protein Visualization
Cryo-EM methods can determine structures of small proteins bound to potential drug candidates.
Alzheimer’s Protein Serves as Natural Antibiotic
Alzheimer's-associated amyloid plaques may be part of natural process to trap microbes, findings suggest new therapeutic strategies.
Slime Mold Reveals Clues to Immune Cells’ Directional Abilities
Study from UC San Diego identifies a protein involved in the directional ability of a slime mold.
How Do You Kill A Malaria Parasite?
Drexel University scientists have discovered an unusual mechanism for how two new antimalarial drugs operate: They give the parasite’s skin a boost in cholesterol, making it unable to traverse the narrow labyrinths of the human bloodstream. The drugs also seem to trick the parasite into reproducing prematurely.
Illuminating Hidden Gene Regulators
New super-resolution technique visualizes important role of short-lived enzyme clusters.
Supressing Intenstinal Analphylaxis in Peanut Allergy
Study from National Jewish Health shows that blockade of histamine receptors suppresses intestinal anaphylaxis in peanut allergy.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,100+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!