Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

LGC Genomics and Covaris, Inc. Announce FFPE DNA Extraction Partnership

Published: Tuesday, June 25, 2013
Last Updated: Tuesday, June 25, 2013
Bookmark and Share
Companies are partnering to develop an innovative solution for the high-throughput extraction of Nucleic Acids from Formalin-Fixed, Paraffin Embedded (FFPE) tissue samples.

Covaris recently introduced a kit for high-yield DNA extraction from FFPE tissue samples. Covaris' patented Adaptive Focused Acoustic™ (AFA) Technology is used to emulsify and separate the paraffin, while simultaneously re-hydrating the tissue sample in an aqueous solution within a few minutes. Covaris Focused-ultrasonicators enable the purely mechanical processing of the samples, eliminating the need for organic solvents in the extraction process. DNA is efficiently extracted from FFPE samples with greater yield when compared to other commercially available solutions. It results in a simplified workflow, which improves reproducibility, reduces hands on time, and ensures the seamless integration with Next Generation Sequencing (NGS) and other analytical applications.
LGC Genomics has a long standing expertise in providing DNA extraction solutions, including a range of extraction technologies and the development of kits and systems optimized for specific applications. LGC Genomics' current product offerings include, sbeadex® magnetic microparticles and Kleargene spin plates for automated extraction of high quality DNA.

Building on the strengths of both companies, LGC Genomics and Covaris will integrate LGC Genomics' DNA purification solution with Covaris FFPE extraction workflow. This collaboration will offer a complete solution, from FFPE tissue to high quality DNA, suitable for high throughput applications with the ability to process thousands of FFPE samples per week.

FFPE is a widely used method for archiving tissue specimens; especially clinical samples. These archived samples are a rich resource for studying gene variations or gene expression profile changes, and have the promise of empowering advancements to clinical diagnostics and personalized medicine. However, extraction of DNA or RNA from FFPE tissue has traditionally been a challenge as it requires removing the paraffin, rehydrating the sample, and reversing the formaldehyde cross-links - resulting in low yields and poor quality of nucleic acid samples. Additionally, the traditional extraction processes require the use of hazardous or difficult-to-handle solvents causing barriers to automation and higher throughput processing. Covaris CEO, Jim Laugharn, commented, "This collaboration will provide a solution to overcome traditional short-comings and barriers. We will improve the extraction workflow and provide higher quality samples and higher quality results in a high throughput environment." Giulio Cerroni, LGC Genomics Managing Director added, "We are delighted to be working with Covaris to develop this application together. Linking our Sbeadex and Kleargene technologies with the Covaris technology will provide our customers in both pathology and research laboratories with a complete solution that will enable them to process FFPE samples significantly more efficiently, whilst also providing high yields, reproducibly."


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More Than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Shedding Light on HIV Vaccine Design
Broadly speaking - Mathematical modelling of host-pathogen coevolution sheds light on HIV vaccine design.
AACC 2016 Sees Clinical Chemistry Labs Drive Precision Medicine Offerings
Biomarker assays to enable precision medicine and risk assessment, mass spec-based tests designed for use in clinical labs large and small, and liquid biopsy technology captured the spotlight at the AACC annual meeting.
Automated Patch Clamping Trends
Learn more about current practices, preferences and metrics in ion channel drug screening using APC technology.
Lab-on-a-Stick: Miniaturised Clinical Testing For Fast Detection Of Antibiotic Resistance
A portable power-free test for the rapid detection of bacterial resistance to antibiotics has been developed by academics at Loughborough University and the University of Reading.
Genetic Ancestry of Cultivated Strawberry Unravelled
UNH scientists constructed a linkage map of the seven chromosomes of the diploid Fragaria iinumae, which allows them to fill in a piece of the genetic puzzle about the eight sets of chromosomes of the cultivated strawberry.
Progress In Vaccination Against Vespid Venom
Researchers at the Helmholtz Zentrum München and the Technical University Munich have presented a method which facilitates a personalised procedure for wasp allergy sufferers.
New Drug Target for Inflammatory Disorders
Penn study finds enigmatic molecules maintain equilibrium between fighting infection and inflammatory havoc.
Breast Cancer Cells Found To Switch Molecular Characteristics
Spontaneous interconversion between HER2-positive and HER2-negative states could contribute to progression, treatment resistance in breast cancer.
Mechanisms of Calcium Blockers
Researchers describe how the fundamental mode of action of two distinct chemical classes of calcium channel blockers differs.
Some Breast Cancer Patients With Low Genetic Risk Could Skip Chemotherapy
Genetic test can help predict survival and guide treatment options.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!