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Genedata at ESACT Announces Expansion into Biopharma Process Development

Published: Tuesday, July 02, 2013
Last Updated: Monday, July 01, 2013
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Established, integrated biologics platform extends scope to support bioprocess development workflows

Genedata, a leading provider of advanced software solutions for drug discovery and life science research, has announced that it is extending its enterprise biologics R&D solution to support bioprocess development workflows. A first-in-class software solution for integrated biopharma data management, Genedata Biologics enables biologics companies to more efficiently discover, develop, and manufacture novel, as well as generic, biotherapeutics. Genedata Biologics provides tailored functionalities to enhance process efficiency, which complement established antibody discovery and protein engineering functionalities. Genedata Biologics presented its latest platform developments that support cell line and process development during the 23rd European Society for Animal Cell Technology (ESACT) Meeting (Lille Grand Palais; June 23 - 26).

Towards an Integrated Platform for Cell and Process Development:  Significant Efficiency and Quality Gains

Genedata Biologics, an enterprise workflow system, now also supports process and cell line development units. The platform provides tools for the optimization of protein expression, purification, and analytics processes. These tools are essential for efficient and successful production of high-quality biologics for R&D and large-scale product manufacturing. Optimizing expression and purification processes requires various groups to work in a division-of-labor environment (e.g. molecular biology, cell line engineering, assays and analytics, and bioprocess development groups). Genedata Biologics captures all relevant data, from the definition of the desired biomolecule's blueprint to the final product, including all production process-relevant parameters (e.g. transfection protocols, cell culture and fermentation conditions, media, purification methods, and product titers and quality parameters). All data are traced back to the plasmids and cell lines and can be analyzed together. The system also integrates with upstream and downstream processes, and now comes with sample and inventory management that streamlines tracking of samples and aliquots.

The system provides easy-to-use, comprehensive, and automated data capture, processing and reporting capabilities. It minimizes duplication of work, eliminates error-prone manual activities, and provides extremely valuable transparency for efficient decision making, so that high-quality proteins can be delivered faster.

"Having successfully supported important workflows in biopharma discovery, we now set our sights on extending Genedata Biologics to biopharma development with an initial focus on cell line and bioprocess development," said Dr. Othmar Pfannes, CEO of Genedata. "Our innovative platform aids in the rapid and systematic development of optimized bioprocesses, and specifically helps to standardize and streamline cell line development. This brings us another step closer in providing our customers with a fully integrated platform that supports the complete biopharmaceutical R&D process."

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