Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Blaze Bioscience and Fred Hutchinson Cancer Research Center Collaborate

Published: Thursday, July 04, 2013
Last Updated: Thursday, July 04, 2013
Bookmark and Share
Collaboration leverages the Hutchinson Center’s research excellence with Blaze drug development expertise.

Blaze Bioscience, Inc. and Fred Hutchinson Cancer Research Center announced a collaboration and option agreement to support the Hutchinson Center’s Optides Discovery Program and advance drug candidates identified using the platform.

Optides, short for “optimized peptides,” are tiny molecules derived from natural organisms such as scorpions, violets and sunflowers. Optides can be instructed to bind to particular kinds of cancer cells, disabling only those cells. They also can be attached to chemotherapy drugs, transforming them into precision therapies that spare healthy cells.

Under the terms of the agreement, Blaze will provide development and commercialization guidance, as well as access to Blaze technology, for optide drug candidates during the discovery phase at the Hutchinson Center. Blaze has the option to exclusively license commercial rights to optide drug candidates that achieve certain criteria. In addition to technology access and support, the Hutchinson Center has received an additional equity stake in Blaze and will receive further payments on each product candidate optioned by Blaze. Any optide candidates not optioned by Blaze will belong fully to the Hutchinson Center including any intellectual property developed or provided by Blaze in the discovery phase for that optide candidate.

Blaze’s first development candidate, BLZ-100, is based on the first optide discovered by the Hutchinson Center. BLZ-100 is a variant of a peptide called chlorotoxin, which was originally derived from scorpion venom. This optide forms the backbone of the Tumor Paint technology previously licensed by Blaze.

“Collaborating on the Optides Program with the Hutchinson Center is a natural extension of our pipeline and utilizes our combined expertise,” said Heather Franklin, co-founder, president and chief executive officer of Blaze. “Our Tumor Paint technology program has maintained its aggressive schedule to advance BLZ-100 from license to clinic in just two years. Helping the Hutchinson Center quickly advance additional optide product candidates with efficient technology transfer followed by rapid entry into the clinic benefit both the Hutchinson Center and Blaze, but more importantly, may ultimately benefit patients.”

“We are pleased to establish this collaboration with Blaze. It is structured to efficiently match the Hutchinson Center’s superb discovery science with Blaze’s industry expertise in drug selection and peptide drug development in efforts to speed the transfer of Hutchinson Center optides discoveries to the clinic,” said Ulrich Mueller, vice president of Industry Relations and Clinical Research Support at the Hutchinson Center. “This will further the Hutchinson Center’s overarching mission to eliminate cancer and related diseases as causes of human suffering and death.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,000+ scientific posters on ePosters
  • More Than 4,400+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Releasing Cancer Cells for Better Analysis
A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Releasing Cancer Cells for Better Analysis
A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Apricot Kernels Pose Risk of Cyanide Poisoning
Eating more than three small raw apricot kernels, or less than half of one large kernel, in a serving can exceed safe levels. Toddlers consuming even one small apricot kernel risk being over the safe level.
Cell Transplant Treats Parkinson’s in Mice
A University of Wisconsin—Madison neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell.
Understanding Female HIV Transmission
Glowing virus maps points of entry through entire female reproductive tract for first time.
Genetic Markers Influence Addiction
Differences in vulnerability to cocaine addiction and relapse linked to both inherited traits and epigenetics, U-M researchers find.
Lab-on-a-Chip for Detecting Glucose
By integrating microfluidic chips with fiber optic biosensors, researchers in China are creating ultrasensitive lab-on-a-chip devices to detect glucose levels.
A lncRNA Regulates Repair of DNA Breaks in Breast Cancer Cells
Findings give "new insight" into biology of tough-to-treat breast cancer.
COPD Linked to Increased Bacterial Invasion
Persistent inflammation in COPD may result from a defect in the immune system that allows airway bacteria to invade deeper into the lung.
Detection of HPV in First-Void Urine
Similar sensitivity of HPV test on first void urine sample compared to cervical smear.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,400+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!