Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

D&A PHARMA Presents 3 Major Clinical Studies at the 14th Congress of ESBRA

Published: Monday, September 09, 2013
Last Updated: Monday, September 09, 2013
Bookmark and Share
Company will present the results of several international clinical studies (essentially GATE 1,GATE 2 and GUM) including a population of 2.500 alcohol-dependent patients.

D&A PHARMA has announced its strong participation in the 14th Congress of European Company of Biomedical Search on the Alcoholism (ESBRA), which will be held in Warsaw from September 8th to 11th.

During this Congress, D&A PHARMA will present the results of several clinical studies (GATE 1, GATE 2 et GUM) for ALCOVER® (Sodium Oxybate), a breakthrough treatment of alcohol dependence.

All presented data confirm that Sodium Oxybate favorably meets the therapeutic objectives set by experts and by health authorities (EMA, FDA) for the management of alcohol-dependence.

• GATE 1 study included 127 dependent patients, confirms the efficacy of ALCOVER® in the processing of the syndrome of weaning occurring at the time of the stop of the alcoholic intoxication.

• GATE 2 study included a 6-month double-blind treatment with ALCOVER® or placebo, followed by a 6-month untreated period. ALCOVER® was statistically significantly better than placebo at 6 months and the difference was maintained at 12 months. Three hundred and fourteen alcohol-dependent patients from 4 European countries participated in GATE 2 study. On September 9th, D&A PHARMA will present in detail the outcomes of these studies in an official satellite symposium of the ESBRA as well as in a poster and oral presentations. The satellite symposium is entitled: « Sodium Oxybate: Breakthrough in the Treatment of Alcohol Withdrawal Syndrome and Maintenance of Alcohol Abstinence ».

These two multicenter studies have been conducted in Germany, Austria, Italy and Poland.

• The GUM study (GHB - Use and Misuse) is a longitudinal retrospective study that has analyzed 604 patient files. Patients had a severe alcohol dependence, and for some of them, co-addictions or psychiatric co-morbidities. The study has been performed from 2005 to 2007 in seven centers from Northern Italy.

The study demonstrated that ALCOVER is effective and safe when prescribed in the therapeutic dose interval: in the treatment of alcoholic withdrawal syndrome (detoxification), 81% of patients were successfully detoxified. In the prevention of relapses and maintenance of alcohol abstinence maintenance, 75% to 80% of patients remained abstinent 12 months after the initiation of alcohol treatment.

Dr Felice Nava, Director of Scientific Committee of the Italian Society of Addiction Medicine (FeDerSerD), commented: “All these studies have proved the efficacy and the safety of Sodium Oxybate on the current criteria of evaluation required by the European Medicines Agency. It is the case both in the treatment of the withdrawal syndrome and in the prevention of alcohol relapses and this, without any addictive effect observed”.

Patrice Debrégeas, chairman of D&A PHARMA, concluded: “We are very proud of all the aggregated clinical data for ALCOVER®. All these long-term studies show the efficacy and the great safety of use of ALCOVER®. In addition to these strong results makes it possible to the patients to avoid to benzodiazepines, strongly sedative drugs, during the detoxification period and to continue the same treatment on the long term, which is unique among anti-alcohol drugs and optimizes significant fact in the treatment of the alcoholic dependence. This is a major competitive advantage and an important benefit for all alcoholic patients. As an independent pharmaceutical company, it is a great honor to present to the largest KOLs’ panel in the field of alcohology and addictology all these major results at a moment when D&A PHARMA is filing for approval in a secured formulation of ALCOVER® several European agencies in order to market the product in the European Union in 2014, while ALCOVER® has been successfully marketed for 20 years in Italy and 14 years in Austria, allowing to treat successfully 350.000 patients who are 100% refunded at 100% by public healthcare organizations”.

In addition to its participation in the 14th Congress of ESBRA, D&A PHARMA will organize on September 7th, 2013, always at Warsaw, its International Expert Board, gathering about thirty leading specialists and fundamental scientists in alcohology and addictology.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More Than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
The Changing Tides of the In Vitro Diagnostics Market
With the increasing focus in personalized medicine, diagnostics plays a crucial role in patient monitoring.
LaVision BioTec Reports on the Neuro Research on the Human Brain After Trauma
Company reports on the work of Dr Ali Ertürk from the Institute for Stroke and Dementia Research at LMU Munich.
NIH Study Shows No Benefit of Omega-3 Supplements for Cognitive Decline
Research was published in the Journal of the American Medical Association.
Less May Be More in Slowing Cholera Epidemics
Mathematical model shows more cases may be prevented and more lives saved when using one dose of cholera vaccine instead of recommended two doses.
Investigating the Vape
Expert independent review concludes that e-cigarettes have potential to help smokers quit.
NIH Launches Human RSV Study
Study aims to understand infection in healthy adults to aid development of RSV medicines, vaccines.
Researchers Discover Synthesis of a New Nanomaterial
Interdisciplinary team creates biocomposite for first time using physiological conditions.
Poor Survival Rates in Leukemia Linked to Persistent Genetic Mutations
For patients with an often-deadly form of leukemia, new research suggests that lingering cancer-related mutations – detected after initial treatment with chemotherapy – are associated with an increased risk of relapse and poor survival.
Flu Remedies Help Combat E. coli Bacteria
Physiologists from the University of Zurich have now discovered why the intestinal bacterium Escherichia coli (E. coli) multiplies heavily and has an inflammatory effect.
Marijuana Genome Unraveled
A study by Canadian researchers is providing a clearer picture of the evolutionary history and genetic organization of cannabis, a step that could have agricultural, medical and legal implications for this valuable crop.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!