Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Santhera Closes License-Back Deal with Takeda

Published: Friday, September 27, 2013
Last Updated: Friday, September 27, 2013
Bookmark and Share
Agreement with Takeda to license back previously granted European rights to Catena® in DMD.

Santhera Pharmaceuticals has announced that it has reached an agreement with Takeda to license back previously granted European rights to Catena® (INN: idebenone) in Duchenne Muscular Dystrophy (DMD).

In a back-loaded deal, Santhera regains European commercialization rights for Catena®. The drug is currently being investigated in a Phase III study in DMD conducted in Europe and in the USA.

In 2007, Takeda Pharmaceutical Company Limited (TSE: 4502, "Takeda") acquired the exclusive marketing rights in Europe and Switzerland for Catena® for the treatment of DMD.

Under the agreement reached, Santhera licenses back all such previously granted rights to increase its strategic flexibility. In return, Takeda is eligible to obtain a percentage from future licensing and/or sales income generated by Santhera in DMD.

In addition, Santhera has obtained the right to cross-reference Takeda's idebenone data for regulatory use in any indication in any territory.

If Santhera makes use of such cross-reference right, Takeda is eligible to obtain a percentage from future licensing and/or sales income generated by Santhera in such indications.

Lastly, both companies agreed to terminate a similar agreement for Friedreich's Ataxia signed in 2005 and Santhera's previously disclosed contingent liability of EUR 1 million payable to Takeda has been waived.

Takeda is eligible to receive Euro 1 million as a percentage from future income generated by Santhera to offset this waiver.

"The agreement we reached today with Takeda clearly increases our strategic flexibility. Potential licensees interested in Catena® in DMD can now be offered global rights to this program", commented Thomas Meier, CEO of Santhera.

Meier continued, "The ongoing DELOS study has recently passed a futility analysis and we expect to report top-line data from the first cohort of patients in this study in the second quarter of 2014. Today's agreement with Takeda also grants us right of cross-reference to certain data which may be needed for any regulatory filings for indications currently being developed or which may be developed in the future."


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More Than 4,600+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Santhera Reports Financial Results
Results for the first half year and transitions towards product company.
Tuesday, September 15, 2015
Santhera Receives European Marketing Authorization for Raxone®
First approved treatment for LHON and first approved treatment for a mitochondrial disease.
Thursday, September 10, 2015
Santhera Receives Rare Pediatric Disease Designation from FDA
FDA has granted designation for idebenone for the treatment of Duchenne Muscular Dystrophy.
Tuesday, August 25, 2015
Santhera Announces First Patient Dosing with Omigapil in CMD
Company announces full patient recruitment of CALLISTO study.
Tuesday, July 21, 2015
CHMP Recommends Granting a Marketing Authorization for Santhera's Raxone®
Raxone® (idebenone) for the treatment of visual impairment in adolescent and adult patients with LHON.
Friday, June 26, 2015
Santhera Update on Pre-NDA Meeting with FDA
Company plans to submit a New Drug Application for Raxone®/Catena® (idebenone) in Duchenne Muscular Dystrophy.
Tuesday, June 16, 2015
Santhera's Positive Phase III Trial in DMD Patients Published in The Lancet
First successful Phase III trial in DMD shows Raxone®/Catena® preserves respiratory function.
Thursday, April 23, 2015
Santhera Receives FDA Fast Track Designation for Raxone®/Catena®
Fast Track designation for the treatment of Duchenne Muscular Dystrophy.
Friday, April 10, 2015
Santhera Repositions Omigapil in Congenital Muscular Dystrophy
Company initiates clinical development program with public-private partners.
Thursday, July 17, 2014
Santhera Announces Successful Outcome of Phase III Study with Catena®/Raxone® in DMD
Positive outcome indicates that Catena®/Raxone® can mitigate respiratory weakness and dysfunction.
Tuesday, May 27, 2014
Santhera Secures Exclusive Rights from NIH
Santhera has obtained the exclusive rights to the use patent for idebenone in ppMS granted in the USA.
Monday, June 10, 2013
Santhera and Ipsen Renegotiate Fipamezole Licensing Agreement
Santhera regains worldwide rights for fipamezole.
Tuesday, January 24, 2012
Santhera Obtains US Patent for Use of Catena® in the Treatment of Muscular Dystrophies
The patent in the United States is supplemented by a similar patent in the European Union granted in 2010.
Wednesday, August 24, 2011
Data from Santhera's RHODOS Study to Be Presented at the European Neurological Society 2011 Meeting
Results from the RHODOS study evaluate the efficacy of Catena® in Leber Hereditary Optic Neuropathy.
Tuesday, June 07, 2011
Fipamezole Transition from Biovail Completed - Program Well Advanced Towards Phase III
Fipamezole is being developed as a potential first treatment of Dyskinesia in Parkinson's Disease.
Wednesday, February 23, 2011
Scientific News
Platelets are the Pathfinders for Leukocyte Extravasation During Inflammation
Findings from the study could help in the prevention and treatment of inflammatory pathologies.
ASMS 2016: Targeting Mass Spectrometry Tools for the Masses
The expanding application range of MS in life sciences, food, energy, and health sciences research was highlighted at this year's ASMS meeting in San Antonio, Texas.
Benchtop Automation Trends
Gain a better understanding of current interest in and future deployment of benchtop automated systems.
Manufactured Stem Cells to Advance Clinical Research
Clinical-grade cell line will enable development of new therapies and accelerate early-stage clinical research.
Dengue Virus Exposure May Amplify Zika Infection
Researchers at Imperial College London have found that the previous exposure to the dengue virus may increase the potency of Zika infection.
Gender Determination in Forensic Investigations
This study investigated the effectiveness of lip print analysis as a tool in gender determination.
Identifying Novel Types of Forensic Markers in Degraded DNA
Scientists have tried to verify the nucleosome protection hypothesis by discovering STRs within nucleosome core regions, using whole genome sequencing.
Proteins in Blood of Heart Disease Patients May Predict Adverse Events
Nine-protein test shown superior to conventional assessments of risk.
Higher Frequency of Huntington's Disease Mutations Discovered
University of Aberdeen study shows that the gene change that causes Huntington's disease is much more common than previously thought.
Starving Stem Cells May Enable Scientists To Build Better Blood Vessels
Researchers from the University of Illinois at Chicago College of Medicine have uncovered how changes in metabolism of human embryonic stem cells help coax them to mature into specific cell types — and may improve their function in engineered organs or tissues.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,600+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!