Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

libragen Celebrates Success in European PolyModE Project

Published: Tuesday, October 01, 2013
Last Updated: Tuesday, October 01, 2013
Bookmark and Share
Biocatalysis and metagenomics used for generation of improved hydrocolloids with potential therapeutic properties.

libragen has been a major contributor to the success of PolyModE (Polysaccharide Modifying Enzymes), a large collaborative research project funded by the European Community. The project, which began in 2009 and ended in April this year, looked at developing novel polysaccharide modifying enzymes for the optimized use of hydrocolloids as, for example, food additives or novel therapeutic agents in the food sciences and medical industries. Researchers focused on six industry-targeted hydrocolloids (alginates, carrageenans, chitosans, glycosaminoglycans, pectins, and xanthan gums) where traditional chemistry fails to achieve a certain desired modification.

libragen is internationally recognized for its expertise in biocatalysis and metagenomics (the study of whole genetic material from environmental samples) and is regularly engaged as a partner in such large research programs. As a key member of this collaboration - which included both academic and industrial partners - libragen successfully developed a high-throughput functional screen for the detection of sulphatase activity and metagenomic screening libraries using environmental samples. As a result of this combined approach, 10 novel sulphatase producers were identified from more than 20000 screened metagenomic clones and the partners triumphed in identifying, characterizing and optimizing novel enzymes for the modification of all six targeted polysaccharides overall.

libragen’s biocatalysis project leader, Dr. Rob Ter Halle, will be presenting how biocatalysis offers significant advantages in comparison to classical chemistry in terms of selectivity, specificity and yield, on 10 October at 14:00 at the Industrial Biotech Forum during Biotechnica 2013, Hannover, (8-10 October). His talk, entitled “Applied biocatalysis to obtain novel glyco-conjugates”, will detail how libragen’s bespoke contract research services increased both manufacturing profitability and competitiveness in the context of a real-world example – the synthesis of the cosmetic ingredient glucosyl conjugate of caffeic acid. In this example, libragen’s advanced technology and expertise yielded a remarkably efficient process founded on the principles of green chemistry. Only water was used as a solvent, no derivatization was required and all reagents were obtained from natural, renewable sources. The end-product has vastly improved solubility and oxidative stability compared to caffeic acid, yielding a higher performance compound that is now efficiently produced at a scale of several hundred kilos, while saving both time and money.

Biotechnica delegates can also visit booth E59 to discover how libragen’s expertise in biocatalysis and metagenomic technologies can be applied to enhance their specific application.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More Than 4,800+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

DSM and LibraGen Sign Agreement to Co-Develop Transaminases for Production of Chiral Amines
DSM and LibraGen, a bacterial diversity-based process and discovery specialist, announced today that they have signed an agreement to co-develop new omega-transaminases for production of chiral amines.
Tuesday, September 16, 2008
Scientific News
Liquid Biopsies: Miracle Diagnostic or Next New Fad?
Thanks to the development of highly specific gene-amplification and sequencing technologies liquid biopsies access more biomarkers relevant to more cancers than ever before.
Connectome Map More Than Doubles Human Cortex’s Known Regions
Researchers at NIH have developed software that automatically detects the “fingerprint” of each of these areas in an individual’s brain scans.
New Mechanism of Tuberculosis Infection
Researchers at UTSW Medical Center have identified a new way that tuberculosis bacteria get into the body, revealing a potential therapeutic angle to explore.
New Therapeutic Targets For Small Cell Lung Cancer Identified
Researchers at UTSW Medical Center have identified a protein termed ASCL1 that is essential to the development of small cell lung cancer and that, when deleted in the lungs of mice, prevents the cancer from forming.
Eliminating Doubt in Criminal Investigations
New ASU certificate to help curb error, misunderstanding in the quest for justice.
Determination of 13 Organic Toxicants in Human Blood
Researchers have utilised liquid-liquid extraction coupling HPLC-MS/MS to identify and quantify organic toxicants in human blood.
A Novel Cell Culture Model For Forensic Biology Experiments
Researchers have developed a new cell culture model which provides an efficient research tool in forensic biology.
Rhino DNA Bank Aids Anti-Poaching Fight
At the University of Pretoria's Veterinary Genetics Laboratory (VGL) at Onderstepoort, Dr Cindy Harper and her team have developed a ground-breaking technique to collect and catalogue DNA from rhinos and rhino horns.
Drug - Gene 'One-Two' Punch Against Cancer
Researchers identify gene-drug combinations that, together, target and kill cancer cells while not targeting healthy cells.
Gut Bacteria Older than Human Species
Some bacteria have lived in the human gut since before we were human, suggesting evolution could have a larger role inhuman bacterial makeup.
Scroll Up
Scroll Down

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,800+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!