Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

libragen Celebrates Success in European PolyModE Project

Published: Tuesday, October 01, 2013
Last Updated: Tuesday, October 01, 2013
Bookmark and Share
Biocatalysis and metagenomics used for generation of improved hydrocolloids with potential therapeutic properties.

libragen has been a major contributor to the success of PolyModE (Polysaccharide Modifying Enzymes), a large collaborative research project funded by the European Community. The project, which began in 2009 and ended in April this year, looked at developing novel polysaccharide modifying enzymes for the optimized use of hydrocolloids as, for example, food additives or novel therapeutic agents in the food sciences and medical industries. Researchers focused on six industry-targeted hydrocolloids (alginates, carrageenans, chitosans, glycosaminoglycans, pectins, and xanthan gums) where traditional chemistry fails to achieve a certain desired modification.

libragen is internationally recognized for its expertise in biocatalysis and metagenomics (the study of whole genetic material from environmental samples) and is regularly engaged as a partner in such large research programs. As a key member of this collaboration - which included both academic and industrial partners - libragen successfully developed a high-throughput functional screen for the detection of sulphatase activity and metagenomic screening libraries using environmental samples. As a result of this combined approach, 10 novel sulphatase producers were identified from more than 20000 screened metagenomic clones and the partners triumphed in identifying, characterizing and optimizing novel enzymes for the modification of all six targeted polysaccharides overall.

libragen’s biocatalysis project leader, Dr. Rob Ter Halle, will be presenting how biocatalysis offers significant advantages in comparison to classical chemistry in terms of selectivity, specificity and yield, on 10 October at 14:00 at the Industrial Biotech Forum during Biotechnica 2013, Hannover, (8-10 October). His talk, entitled “Applied biocatalysis to obtain novel glyco-conjugates”, will detail how libragen’s bespoke contract research services increased both manufacturing profitability and competitiveness in the context of a real-world example – the synthesis of the cosmetic ingredient glucosyl conjugate of caffeic acid. In this example, libragen’s advanced technology and expertise yielded a remarkably efficient process founded on the principles of green chemistry. Only water was used as a solvent, no derivatization was required and all reagents were obtained from natural, renewable sources. The end-product has vastly improved solubility and oxidative stability compared to caffeic acid, yielding a higher performance compound that is now efficiently produced at a scale of several hundred kilos, while saving both time and money.

Biotechnica delegates can also visit booth E59 to discover how libragen’s expertise in biocatalysis and metagenomic technologies can be applied to enhance their specific application.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More Than 4,600+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

DSM and LibraGen Sign Agreement to Co-Develop Transaminases for Production of Chiral Amines
DSM and LibraGen, a bacterial diversity-based process and discovery specialist, announced today that they have signed an agreement to co-develop new omega-transaminases for production of chiral amines.
Tuesday, September 16, 2008
Scientific News
Platelets are the Pathfinders for Leukocyte Extravasation During Inflammation
Findings from the study could help in the prevention and treatment of inflammatory pathologies.
ASMS 2016: Targeting Mass Spectrometry Tools for the Masses
The expanding application range of MS in life sciences, food, energy, and health sciences research was highlighted at this year's ASMS meeting in San Antonio, Texas.
Benchtop Automation Trends
Gain a better understanding of current interest in and future deployment of benchtop automated systems.
Manufactured Stem Cells to Advance Clinical Research
Clinical-grade cell line will enable development of new therapies and accelerate early-stage clinical research.
Dengue Virus Exposure May Amplify Zika Infection
Researchers at Imperial College London have found that the previous exposure to the dengue virus may increase the potency of Zika infection.
Gender Determination in Forensic Investigations
This study investigated the effectiveness of lip print analysis as a tool in gender determination.
Identifying Novel Types of Forensic Markers in Degraded DNA
Scientists have tried to verify the nucleosome protection hypothesis by discovering STRs within nucleosome core regions, using whole genome sequencing.
Proteins in Blood of Heart Disease Patients May Predict Adverse Events
Nine-protein test shown superior to conventional assessments of risk.
Higher Frequency of Huntington's Disease Mutations Discovered
University of Aberdeen study shows that the gene change that causes Huntington's disease is much more common than previously thought.
Starving Stem Cells May Enable Scientists To Build Better Blood Vessels
Researchers from the University of Illinois at Chicago College of Medicine have uncovered how changes in metabolism of human embryonic stem cells help coax them to mature into specific cell types — and may improve their function in engineered organs or tissues.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,600+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!