Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Probiotics Reduce Piglet Pathogens

Published: Tuesday, November 19, 2013
Last Updated: Tuesday, November 19, 2013
Bookmark and Share
Piglets fed probiotic Enterococcus faecium showed reduced numbers of potentially pathogenic Escherichia coli strains in their intestines.

The research is important, because in 2006 the European Union prohibited the feeding of antibiotics to livestock as growth promoters. Therefore, the research team sought to investigate whether probiotics could substitute for antibiotics, by reducing pathogen populations in the intestines, says first author Carmen Bednorz of Freie Universitat Berlin, Germany. The study was published ahead of print in the journal Applied and Environmental Microbiology.

“We found a clear reduction of E. coli strains possessing typical genes for extra-intestinal pathogenic E. coli (ExPEC),” says Bednorz. The reduction was particularly noticeable in strains that adhere to the intestinal mucosa (and less so in the feces), which was “very interesting,” she says, because “ExPEC typically harbor a lot of adhesion genes that promote colonization of the mucosa.”

Antimicrobials are thought to promote growth in industrially grown livestock because without them, the rationale goes, in such close quarters, a surfeit of pathogens would slow growth. “Our data suggest that the feeding of probiotics could substitute for antimicrobials as growth promoters,” says Bednorz. “This could help to reduce the burden of antimicrobial resistance,” she adds.

In previous studies, the working groups from the Institute of Microbiology and Epizootics at Freie Universitat Berlin found that feeding E. faecium probiotic did not change the general swine intestinal microbiota, but reduced infections by Chlamydia spp. and pathogenic E. coli, according to the report.

In the study, Bednorz and her collaborators compared piglets fed with E. faecium to those in a control group. They collected more than 1,400 samples of E. coli from piglets of different ages, and from different parts of the intestine.

While a number of strains of E. coli are pathogenic, non-pathogenic E. coli “contributes to the maintenance of the microbial gut balance,” according to the report. These were relatively unaffected by the feeding of E. faecium, which “did not influence the overall intestinal E. coli diversity, corroborating previous data,” according to the report. Thus, the researchers conclude, the results suggest that E. faecium inhibits pathogenic E. coli from becoming attached to the intestinal mucosa.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,000+ scientific posters on ePosters
  • More Than 4,400+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Universal Flu Vaccine in the Works
A new study has demonstrated a potential strategy for developing a flu vaccine with potent, broad protection.
Wednesday, July 22, 2015
Single Enzyme is Necessary for Development of Diabetes
12-LO enzyme promotes the obesity-induced oxidative stress in the pancreatic cells.
Wednesday, August 20, 2014
Gut Microbes Affect MicroRNA Response to Bacterial Infection
When it comes to fighting off pathogens like Listeria, your best allies may be the billions of microorganisms that line your gut.
Wednesday, December 18, 2013
Antibiotic Residues in Sausage Meat May Promote Pathogen Survival
Antibiotic residues in uncured pepperoni or salami meat are potent enough to weaken helpful bacteria that processors add to acidify the sausage to make it safe for consumption.
Tuesday, September 04, 2012
Scientific News
Computational Model Finds New Protein-Protein Interactions
Researchers at University of Pittsburgh have discovered 500 new protein-protein interactions (PPIs) associated with genes linked to schizophrenia.
Experimental Drug Cancels Effect from Key Intellectual Disability Gene
A University of Wisconsin—Madison researcher who studies the most common genetic intellectual disability has used an experimental drug to reverse — in mice — damage from the mutation that causes the syndrome.
MicroRNA Pathway Could Lead to New Avenues for Leukemia Treatment
Cancer researchers at the University of Cincinnati have found a particular signaling route in microRNA (miR-22) that could lead to targets for acute myeloid leukemia, the most common type of fast-growing cancer of the blood and bone marrow.
Bioreactors Ready for the Big Time
Bioreactors are passive filtration systems that can reduce nitrate losses from farm fields.
Analysis of Dog Genome will Provide Insight into Human Disease
An important model in studying human disease, the non-coding RNA of the canine genome is an essential starting point for evolutionary and biomedical studies – according to a new study led by The Genome Analysis Centre (TGAC).
‘Mini-Brains’ to Study Zika
Novel tool expected to speed research on brain and drug development.
Finding Factors That Protect Against Flu
A clinical trial examining the body’s response to seasonal flu suggests new approaches for evaluating the effectiveness of seasonal flu vaccines.
New Insights into Gene Regulation
Researchers have solved the three-dimensional structure of a gene repression complex that is known to play a role in cancer.
Controlling RNA in Living Cells
Modular, programmable proteins can be used to track or manipulate gene expression.
Common Class of Cancer Drugs May Not Lead to Cognitive Decline
UCLA study refutes 2015 research suggesting anthracyclines could cause memory loss, other impairments.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,400+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!