Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Labcyte Receives $1 Million NCI Award

Published: Friday, November 22, 2013
Last Updated: Friday, November 22, 2013
Bookmark and Share
The award will be used to create an innovative process to detect cancer-related proteins in samples, with initial work in breast cancer detection.

The unsurpassed precision and accuracy of Labcyte acoustic liquid handling enables biomarker detection by measuring multiple proteins with a MALDI mass spectrometer.  Recent work with the Canary Center at Stanford, also supported by the National Cancer Institute, showed the ability to achieve the sensitivity required for quantifying very small amounts of proteins associated with ovarian cancer. Measuring the amount of multiple proteins, and at lower cost, is an essential step in developing new diagnostic tools for disease treatment and monitoring.

This cutting-edge process encompasses stable standards and capture of biomarkers with antibodies and expects to achieve greater throughput than traditional liquid chromatography-mass spectrometric approaches.  The utility of this technique will be tested by simultaneously analyzing 16 different biomarkers, run in quadruplicate, to simulate the analysis of 64 unique biomarkers.  The process has the potential to expand to a greater number of biomarkers as well.  It may enable significant advances in diagnostics and discovery.

"I am particularly enthusiastic about participating with Labcyte on the further development of their protein multiplexed biomarker detection platform,” said Dr. Mark Stolowitz, Director of the Proteomics Core Facility at the Canary Center at Stanford for Cancer Early Detection.  “This novel immunoaffinity mass spectrometry based approach exploits MALDI-TOF-MS for detection of proteotypic peptides. The platform affords sensitivity comparable to that of triple-quad mass spectrometers while providing significantly greater throughput and better precision than that obtainable from LC-MS/MS based approaches. Over the next few years, the Labcyte platform should provide the high throughput biomarker verification/validation solution that researchers have sought in conjunction with the emergence of clinical proteomics."

In addition to working with the Canary Center, the Labcyte project includes collaboration with the Fred Hutchinson Cancer Research Center in Seattle, Washington.

“We are excited to work with Dr. Stolowitz to explore the potential advantages of the Labcyte platform to increase the throughput beyond that of existing immuno-MRM assays,” said Dr. Amanda Paulovich, an associate member of the Clinical Research Division at the Fred Hutchinson Cancer Research Center.

“Better identification and quantification of multiple biomarkers are critical tools for researchers and clinicians to fight cancer and a wide variety of other diseases,” said Rich Ellson, CTO of Labcyte.  “The unique, revolutionary aspects of acoustic dispensing are essential for the process. We are eager to work with Dr. Stolowitz and Dr. Paulovich, as this could become fundamental for biomarker development.”

This project has been funded in whole or in part with Federal funds from the National Cancer Institute, National Institute of Health and Human Services under Contract No. HHSN261201300089C.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More Than 4,800+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Spotlight on Acoustic Liquid Handling
Journal of Laboratory Automation special issue highlights how acoustic liquid handling enables breakthrough innovations.
Tuesday, January 26, 2016
Labcyte Announces Partnership with AstraZeneca
Partnership to develop new fully acoustic liquid handling system for drug screening.
Saturday, November 21, 2015
Labcyte Announces Collaboration with AstraZeneca
Companies collaborate to use acoustic dispensing combined with mass spectrometry to greatly advance drug discovery applications.
Wednesday, September 25, 2013
Moving Liquids with Sound Helps Identify Drug Candidates that Traditional Lab Techniques Miss
A paper published by the journal PLOS ONE, May 1, 2013, demonstrates that the technique used to transfer compound solutions does indeed matter.
Friday, May 03, 2013
Labcyte Inc. Closes $5.3 Million Financing
Privately-held company with products that advance acoustic liquid handling closes a Series D financing.
Thursday, January 10, 2013
Labcyte and FIMM Announce a Collaboration Enabling “Real-Time” Science to Advance Personalized Medicine in Cancer Treatments
Collaboration expected to further the development of personalized medicine in cancer treatment.
Tuesday, January 08, 2013
Cancer Research Technology Selects the Labcyte Access™ Laboratory Workstation
Labcyte Access workstation to automate the production of assay-ready plates used in CRT's high-throughput cell based screening program
Monday, June 25, 2012
Labcyte Secures NIH Funding
The award of $196K from the National Cancer Institute will fund a collaborative cancer biomarker validation program with the Canary Center of Stanford University.
Wednesday, November 09, 2011
Labcyte Awarded 1st Patent in China
Labcyte has announced the grant of its first patent in China. Patent CN 101035681B describes how acoustic energy is used to assess the characteristics of any fluid in real time to optimize its transfer.
Thursday, September 30, 2010
Labcyte Awarded 40th US Patent
Patent number 7,717,544 describes how in real time acoustic energy is optimized to transfer a droplet of any fluid.
Wednesday, August 25, 2010
Labcyte Signs Bioscreen Instruments as Exclusive Distributor in India
Labcyte, the developer of acoustic liquid transfer, with systems in all top 10 pharmaceutical companies, today announced the selection of Bioscreen Instruments Pvt. Ltd. as its exclusive distributor in India.
Wednesday, September 23, 2009
Labcyte Awarded Second Japanese Patent
Patent covers the design for acoustics used for cell sorting and transfer.
Wednesday, August 19, 2009
Labcyte Echo Acoustic Liquid Handler an Essential Component of Pharmaceutical High-Throughput Screening
Recent issue of JBS emphasizes the importance of acoustic liquid handling in drug discovery.
Friday, August 07, 2009
Labcyte Awarded U. S. Patent Describing the Acoustic Transfer of Droplets into Small Openings Moving liquids with Sound™
The patent describes the acoustic transfer of fluid droplets into openings less than 300 microns in diameter.
Thursday, November 06, 2008
Portrait™ 630 Reagent Multi-Spotter Wins Technology Prize at MipTec 10th Anniversary Conference
The European Laboratory Robotics Interest Group has selected the Labcyte Portrait 630 reagent multi-spotter as the winner of its annual Technology Prize.
Tuesday, May 22, 2007
Scientific News
Liquid Biopsies: Miracle Diagnostic or Next New Fad?
Thanks to the development of highly specific gene-amplification and sequencing technologies liquid biopsies access more biomarkers relevant to more cancers than ever before.
Core-Shell Columns in HPLC: Food Analysis Applications
Explore the most recent applications of core-shell columns in food analysis.
Review of the Analysis of Haemoglobin A1c for Diabetes Diagnostics
This paper aims to clarify methods, units, quality requirements, reference and cutoff limits for hemoglobin A1c (HbA1c) and ratio of blood glucose/HbA1c on the basis of the results from Finnish quality control surveys by comparing them to the literature.
Colon Cancer Blocked in Mice
Case Western Reserve University Researchers block common type of colon cancer tumour in mice, laying groundwork for human clinical trial.
New Centre Offers Ultra-Speed Protein Analysis
UW-Madison researchers to establish development centre for next-gen protein measurement technologies.
Disrupting Tumour-Promotion in Humans
Researchers have modified an existing protein to represses a specific cancer-promoting ‘message’ within cells.
Protein Nanocages Could Improve Drug Design and Delivery
HHMI scientists have designed and built 10 large protein icosahedra that are similar to viral capsids that carry viral DNA.
Vaccine Strategy Targets Multiple Influenza Viruses
Scientists have identified vaccine-induced antibodies that can neutralize strains of influenza virus that infect humans.
Connectome Map More Than Doubles Human Cortex’s Known Regions
Researchers at NIH have developed software that automatically detects the “fingerprint” of each of these areas in an individual’s brain scans.
Discovered Through ‘Big Data’ Analysis
Researchers at the SBP have identified over 100 new genetic regions that affect the immune response to cancer.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,800+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!