Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Validated and Stable Ion Channels Cell Lines for Gene and Function Researches

Published: Friday, December 06, 2013
Last Updated: Friday, December 06, 2013
Bookmark and Share
Creative Biomart’s well-established technique allows expression in cell lines at over a million molecules per cell surface and allows in-depth studies of biophysical properties of ion channels as well as functional studies on proteins.

Ion channels are pore-forming membrane proteins. Hundreds of different types of ion channel have been identified in the membranes of all biological cells. They are reliable and invaluable tools for safety assessment and are available in various cellular backgrounds.

Ion channels are essential for life and play a fundamental role in physiological and biological processes, nervous system, cells, drug target/delivery etc. A multitude of diseases result from the disruption of normal ion channel function. Disorders resulting from a mutation in the gene encoding an ion channel or its regulatory proteins are called channelopathies. Common channelopathies include cystic fibrosis, long QT syndrome and epilepsy. Ion channels are also involved in non-genetic diseases, such as diarrhea, which is mediated by toxicological effects on ion channel function.

Creative Biomart’s well-established technique allows expression in cell lines at over a million molecules per cell surface and allows in-depth studies of biophysical properties of ion channels as well as functional studies on proteins.

These ion channels products are validated for gene, protein, structure, function, and pharmacology. And their performance is characterized. The product lines include:

  • 5-HT3 receptors
  • Acid-sensing (proton-gated) ion channels
  • Calcium-activated potassium channels
  • Chloride channels
  • Cyclic nucleotide-regulated channels
  • Epithelial sodium channels
  • GABAA receptors
  • Inward rectifier potassium channels
  • Ionotropic purinergic receptors
  • Ligand-gated cation channels
  • Nicotinic acetylcholine receptors
  • Transient Receptor Potential channels
  • Voltage-gated calcium channels
  • Voltage-gated potassium channels
  • Voltage-gated sodium channels

Creative Biomart offers the products to help you uncover the function of these channels and elucidate their role in disease.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More Than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Point of Care Diagnostics - A Cautious Revolution
Advances in molecular biology, coupled with the miniaturization and improved sensitivity of assays and devices in general, have enabled a new wave of point-of-care (POC) or “bedside” diagnostics.
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.
One Step Closer to Precision Medicine for Chronic Lung Disease Sufferers
A study led by University of North Carolina at Chapel Hill, and National Jewish Health, has provided evidence of links between SNPs and known COPD blood protein biomarkers.
Charles River Acquires Agilux
Enhances Charles River’s early-stage capabilities in bioanalytical services.
Scientists Find Lethal Vulnerability in Treatment-Resistant Lung Cancer
The study describes how the drug Selinexor killed lung cancer cells and shrank tumors in mice when used against cancers driven by the aggressive and difficult-to-treat KRAS cancer gene.
How Baby’s Genes Influence Birth Weight And Later Life Disease
The large-scale study could help to target new ways of preventing and treating these diseases.
Genes Underlying Dogs’ Social Ability Revealed
The social ability of dogs is affected by genes that also seem to influence human behaviour, according to a new study from Linköping University in Sweden.
‘Cellbots’ Chase Down Cancer, Deliver Drugs Directly to Tumors
Programmable T cells shown to be versatile, precise, and powerful in lab studies.
Drug to Treat Alcohol Use Disorder Shows Promise Among Drinkers With High Stress
The findings suggest that potential future studies with drugs targeting vasopressin blockade should focus on populations of people with AUD who also report high levels of stress.
C Dots Show Powerful Tumor Killing Effect
Nanoparticles known as Cornell dots, or C dots, have shown great promise as a therapeutic tool in the detection and treatment of cancer.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!