Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

University of Bristol Collaborates with Affymetrix on Genotyping Arrays

Published: Wednesday, January 15, 2014
Last Updated: Wednesday, January 15, 2014
Bookmark and Share
Results from the array presented at the 2014 Plant and Animal Genome conference.

Affymetrix, Inc. and University of Bristol, Bristol, UK, have announced that they have collaboratively designed a wheat genotyping array and analyzed data from experiments as part of an effort to understand wheat genetics and breeding with a goal of ensuring guaranteed sustainable production.

Axiom® Wheat Genotyping Array (Axiom Wheat Array), consisting of 817,000 markers, was designed for the University of Bristol as part of the Biotechnology and Biological Sciences Research Council (BBSRC)-funded Wheat Improvement Strategic Program (WISP).

The aim of WISP is to produce new and novel wheat germplasm via three complementary "pillars" (landraces, synthetics, and ancestral gene introgression), each of which will broaden the pool of genetic variation in elite wheat cultivars by a different route.

The design of Axiom Wheat Array is unique because it includes functional and positional annotation information for a variety of wheat species.

The SNPs on Axiom Wheat Array include markers from hexaploid landraces and those from the synthetic and ancestral lines exhibiting different ploidy levels.

Results from the array will be presented at the 2014 Plant and Animal Genome conference (PAG XXII), in San Diego, California.

“The results from Axiom Wheat Array are fantastic and have helped WISP achieve one of the main goals, which is to track the different segments of the 'wheat relative' line and incorporate them into hexaploid bread wheat through the breeding process. The follow-on focused arrays will offer wheat breeders the capability to understand polymorphisms between their current breeding lines,” stated Professor Keith Edwards, project leader and professor of Cereal Functional Genomics at the School of Biological Sciences and member of the Cabot Institute, University of Bristol. “We were thrilled to be able to complete the design and analysis in less than three months and in time to present the results at the Plant and Animal Genome meeting. This was made possible mainly because of the expertise, commitment, and collaborative efforts of the bioinformatics and product support teams at Affymetrix.”

“We are pleased to be able to support the goals of the University of Bristol and contribute efforts to help sustain wheat production in the face of challenges from a growing world population and climate change,” said Dr. Andy Last, Executive Vice President and Chief Operating Officer at Affymetrix. “The Axiom platform enables researchers to publish results sooner and breeders to accelerate their genomic programs. The platform’s superior capabilities are transforming and modernizing custom genotyping capabilities accessible to the agricultural, scientific, and applied community at large.”

A subset of the 817,000 markers found on Axiom Wheat Array will be transferred with 100 percent fidelity onto Axiom 384HT-format arrays to create multiple focused wheat array designs. Each of these Axiom wheat array designs will contain approximately 35,000 markers and each design is expected to serve a different purpose in wheat breeding.

The 384HT format enables ultra high-throughput processing of 384 samples simultaneously and will be used to screen thousands of samples in a highly cost-effective manner. Affymetrix will make these new Axiom arrays publicly available before the spring wheat season.

With Affymetrix’ advanced bioinformatics and innovative design strategies, Axiom genotyping array designs routinely support genome-wide genotyping and accurately call the genotypes of both diploid and polyploid species.

The Axiom Wheat Genotyping arrays in the 384HT format will complement the catalog of Axiom Genotyping Arrays for Agrigenomics that are available for multiple species including salmon, maize, strawberry, rose, bovine, chicken, and buffalo. These products have been used for genome-wide association studies, quantitative trait locus mapping, genome mapping, and breeding activities that make use of marker-assisted selection and genomic selection.

As scientists make progress in decoding genomes of various plants, animals, and fish using next-generation sequencing platforms, they can advance their research and commercial objectives by translating those discoveries to routine applications on the Axiom platform.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 4,000+ scientific posters on ePosters
  • More Than 5,300+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Thermo Acquires Affymetrix
Thermo Fisher Scientific and Affymetrix, has announced that Thermo Fisher has completed its previously announced acquisition of Affymetrix for $14.00 per share in cash, for a total purchase price of approximately $1.3 billion.
Friday, April 01, 2016
Groupe Grimaud Chooses Affymetrix Genotyping Arrays
Affymetrix, Inc. has announced that one of the world’s largest producers of breeding chickens – Roussay, France-based Groupe Grimaud – will use the Axiom® genotyping platform from Affymetrix in its genomic selection and poultry breeding program.
Thursday, February 25, 2016
Bio-Genesys, Affymetrix Partner
Partnership to offer animal genomic testing services to professional farming operations.
Wednesday, January 13, 2016
Thermo Fisher Scientific to Acquire Affymetrix
Strengthens leadership in biosciences and genetic analysis.
Monday, January 11, 2016
Affymetrix, Reveal Biosciences Partner
Partnership agreement to offer RNA ISH tissue staining, imaging, and image analysis services.
Thursday, December 03, 2015
Affymetrix and Athletigen Partner
Partnership agreement to advance genetics in human athletic performance.
Thursday, October 29, 2015
Affymetrix and Luminex Announce Distribution Agreement
Agreement for multiplexed assay instrument platform.
Friday, October 16, 2015
Green Super Rice Project Selects Affymetrix Genotyping Platform for Developing New Rice Varieties
The Green Super Rice (GSR) project includes building a highly efficient genotyping platform for the large-scale molecular breeding activities within the international rice research community.
Tuesday, September 22, 2015
Affymetrix, BioRealm, RUCDR Ally
Affymetrix, BioRealm, and RUCDR Infinite Biologics today announced a strategic alliance to genotype the National Institute of Drug Abuse biorepository.
Wednesday, July 08, 2015
Affymetrix Acquires Assets of Eureka Genomics
Aquisition will enable provision of high throughput and economical crop and animal genotyping.
Thursday, May 14, 2015
CollabRx, Affymetrix To Develop Analytical Tools For Integrated Clinical Cancer Panels
The overall objective of the partnership is to provide scientific knowledge for biomarker CNV profiles in cancer.
Wednesday, April 16, 2014
Affymetrix Reports 2013 First Quarter Results
Affymetrix, Inc. reported its operating results for the three months ended March 31, 2013.
Wednesday, May 01, 2013
Affymetrix and BioDiscovery Announce Software for Analysis of Whole Genome Copy Number Data
Generated from FFPE solid tumor samples for accelerating cancer translational research.
Thursday, April 11, 2013
Ingenuity Systems and Affymetrix Partner
Companies collaborate to eliminate microarray expression analysis bottleneck.
Monday, April 08, 2013
Affymetrix Announces Collaboration with Centre for Proteomic and Genomic Research (CPGR)
CPGR will provide gene expression and Axiom genotyping services to African researchers using GeneTitan® Multi-Channel (MC) Instrument.
Tuesday, November 20, 2012
Scientific News
Big Genetics in BC: The American Society for Human Genetics 2016 Meeting
Themes at this year's meeting ranged from the verification, validation, and sharing of data, to the translation of laboratory findings into actionable clinical results.
Stem Cells in Drug Discovery
Potential Source of Unlimited Human Test Cells, but Roadblocks Remain.
Automated Low Volume Dispensing Trends
Gain a better understanding of the current and future market requirements for fully automated LVD systems.
Cancer Genetics: Key to Diagnosis, Therapy
When applied judiciously, cancer genetics directs caregivers to the right drug at the right time, while sparing patients of unnecessary or harmful treatments.
Unique Visual Stimulation May Be New Treatment for Alzheimer’s
Noninvasive technique reduces beta amyloid plaques in mouse models of Alzheimer’s disease.
Major Neuroscience Initiative Launched
Tianqiao and Chrissy Chen Institute invest $115 million to further expand neuroscience research, while Caltech construct $200 million biosciences complex.
Making It Personal
Cancer vaccine linked to increased immune response against leukemia cells.
Genetics Control Regenerative Properties Of Stem Cells
Researchers define how genetic factors control regenerative properties of blood-forming stem cells.
Diabetes Missing Link Discovered
Researchers from the University of Auckland have shown that beta catenin plays a vital role in the control of insulin release from the pancreas.
Study Reveals New Role for Hippo Pathway in Suppressing Cancer Immunity
Hippo pathway signaling regulates organ size by moderating cell growth, apoptosis and stem cell renewal, but dysregulation contributes to cancer development.
Scroll Up
Scroll Down
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
4,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,300+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!