Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Swiss Cheese Crystal, or High-Tech Sponge?

Published: Tuesday, January 28, 2014
Last Updated: Tuesday, January 28, 2014
Bookmark and Share
The remarkable properties of a new, porous material could lead to advances in microscopic sponging

The sponges of the future will do more than clean house.

Picture this, for example: Doctors use a tiny sponge to soak up a drug and deliver it directly to a tumor. Chemists at a manufacturing plant use another to trap and store unwanted gases.

These technologies are what University at Buffalo Assistant Professor of Chemistry Jason Benedict, PhD, had in mind when he led the design of a new material called UBMOF-1. The material — a metal-organic framework, or “MOF” — is a hole-filled crystal that could act as a sponge, capturing molecules of specific sizes and shapes in its pores.

Swiss cheese-like MOFs are not new, but Benedict’s has a couple of remarkable qualities:

• The crystal’s pores change shape when hit by ultraviolet light. This is important because changing the pore structure is one way to control which compounds can enter or exit the pores. You could, for instance, soak up a chemical and then alter the pore size to prevent it from escaping. Secure storage is useful in applications like drug delivery, where “you don’t want the chemicals to come out until they get where they need to be,” Benedict says.

• The crystal also changes color in response to ultraviolet light, going from colorless to red. This suggests that the material’s electronic properties are shifting, which could affect the types of chemical compounds that are attracted into the pores.

Benedict’s team reported on the creation of the UBMOF on Jan. 22 in the journal Chemical Communications. The paper’s coauthors include chemists from UB and Penn State Hazleton.

“MOFs are like molecular sponges — they’re crystals that have pores,” Benedict said.

“Typically, they are these passive materials: They’re static. You synthesize them, and that’s the end of the road,” he added. “What we’re trying to do is to take these passive materials and make them active, so that when you apply a stimulus like light, you can make them change their chemical properties, including the shape of their pores.”

Benedict is a member of UB’s New York State Center of Excellence in Materials Informatics, which the university launched in 2012 to advance the study of new materials that could improve life for future generations.

To force UBMOF-1 respond to ultraviolet light, Benedict and colleagues used some clever synthetic chemistry.

MOF crystals are made from two types of parts — metal nodes and organic rods — and the researchers attached a light-responsive chemical group called a diarylethene to the organic component of their material.

Diarylethene is special because it houses a ring of atoms that is normally open but shuts when exposed to ultraviolet light.

In the UBMOF, the diarylethene borders the crystal’s pores, which means the pores change shape when the diarylethene does.

The next step in the research is to determine how, exactly, the structure of the holes is changing, and to see if there’s a way to get the holes to revert to their original shape.

Rods containing diarylethene can be forced back into the “open” configuration with white light, but this tactic only works when the rods are alone. Once they’re inserted into the crystal, the diarylethene rings stay stubbornly closed in the presence of white light.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More Than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Brain Equation: Subtract Protein, Generate Myelin-Making Cells
A new way to generate oligodendrocytes has potential to enhance treatments for brain injury, MS, Alzheimer’s and more.
Thursday, August 20, 2015
Scientists Grow Human Serotonin Neurons in Petri Dish
The advance could facilitate the discovery of new antidepressants and drugs for illnesses involving serotonin.
Monday, August 10, 2015
Slinky Lookalike “Hyperlens” Helps Us See Tiny Objects
The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists’ ability to observe single molecules.
Tuesday, May 26, 2015
UB and Roswell Park receive $1.85M Grant to Launch Stem Cell Research Program
The program will bring together 18 faculty members to advance translation of stem cell breakthroughs into cell therapies.
Monday, May 18, 2015
New Imaging Technique Captures Protein Vibrations
Using a technique based on terahertz near-field microscopy scientists have for the first time observed in detail the vibrations of lysozyme.
Friday, January 17, 2014
A Novel Pathway for a Mucosal TB Vaccine
Custom-designed adjuvants, developed at UB, boost immune responses against tuberculosis.
Friday, February 01, 2013
Hybrid Nanoparticles for Multimodal Medical Imaging
The grant will fund research in which two or more medical imaging techniques are combined to provide complementary information.
Thursday, October 05, 2006
Chemical Sensors to Sniff out Diseases in Human Breath
Researchers are developing a Breathalyzer-type device to recognize biomarkers for certain diseases.
Tuesday, February 14, 2006
Scientific News
The Changing Tides of the In Vitro Diagnostics Market
With the increasing focus in personalized medicine, diagnostics plays a crucial role in patient monitoring.
LaVision BioTec Reports on the Neuro Research on the Human Brain After Trauma
Company reports on the work of Dr Ali Ertürk from the Institute for Stroke and Dementia Research at LMU Munich.
NIH Study Shows No Benefit of Omega-3 Supplements for Cognitive Decline
Research was published in the Journal of the American Medical Association.
Less May Be More in Slowing Cholera Epidemics
Mathematical model shows more cases may be prevented and more lives saved when using one dose of cholera vaccine instead of recommended two doses.
Investigating the Vape
Expert independent review concludes that e-cigarettes have potential to help smokers quit.
NIH Launches Human RSV Study
Study aims to understand infection in healthy adults to aid development of RSV medicines, vaccines.
Researchers Discover Synthesis of a New Nanomaterial
Interdisciplinary team creates biocomposite for first time using physiological conditions.
Poor Survival Rates in Leukemia Linked to Persistent Genetic Mutations
For patients with an often-deadly form of leukemia, new research suggests that lingering cancer-related mutations – detected after initial treatment with chemotherapy – are associated with an increased risk of relapse and poor survival.
Flu Remedies Help Combat E. coli Bacteria
Physiologists from the University of Zurich have now discovered why the intestinal bacterium Escherichia coli (E. coli) multiplies heavily and has an inflammatory effect.
Marijuana Genome Unraveled
A study by Canadian researchers is providing a clearer picture of the evolutionary history and genetic organization of cannabis, a step that could have agricultural, medical and legal implications for this valuable crop.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!