Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

3D Biomatrix Announces Allowance of U.S. Patent

Published: Thursday, February 06, 2014
Last Updated: Thursday, February 06, 2014
Bookmark and Share
Cell culture technology uniquely addresses 3D spheroid and embryoid body growth challenges.

3D Biomatrix, Inc. announce the Notice of Allowance of its U.S. Patent for technology included in the Perfecta3D  Hanging Drop Plates, a novel platform that makes 3D spheroid and embryoid body growth, along with an array of co-cultures, simple and inexpensive to perform. The patent entitled “Hanging Drop Devices, Systems and/or Methods” covers several core technologies: 

• The development of a complete hanging drop system that allows the performance of cell analysis in individual hanging drops within a standard 96- or 384-well platform. 

• The specific design of the Perfecta3D Hanging Drop Plate, which allows the growth of one spheroid or embryoid body per well without adherence to a plastic surface or other substance. 

• The inclusion of a water or media reservoir that acts as a humidity source to alleviate the commonly-encountered hanging drop evaporation problem. 

Researchers have long tested drug compounds and other factors affecting cell growth on flat surfaces in two dimensions (2D), but 2D cell cultures do not accurately represent how cells behave in the three-dimensional body. 3D cell cultures grown in the Perfecta3D Hanging Drop Plates allow researchers to recapitulate these characteristics in vitro, providing a more physiologically-relevant model. 3D Biomatrix’s Hanging Drop Plates facilitate the consistent and controllable growth of small spherical cellular 3D clusters in a well-plate format, allowing researchers to test compounds and other factors in a 3D environment that reflects the human body. 

3D Biomatrix and the University of Michigan are listed as the assignees of the patent. 3D Biomatrix holds an exclusive license for worldwide rights to the intellectual property covered by this patent. The inventors of the Perfecta3D technology include Shuichi Takayama, a professor having a joint appointment in the Department of Biomedical Engineering and Macromolecular Science and Engineering at the University of Michigan, Yi-Chung Tung, Amy Yu-Ching Hsiao and Edward Jan. Dr. Takayama is a member of 3D Biomatrix’s Scientific Advisory Board. 

“The allowance of this patent is an important milestone, and we will continue to expand our IP portfolio. Life science and drug discovery researchers want more relevant tools in their toolbox. Although the hanging drop technology has been used for decades, the available techniques were difficult to use making it challenging to reproduce results consistently. The 96- and 384-well Perfecta3D Hanging Drop Plates make spheroid growth, long- and short-term cultures, and expansive co-culture models simple to perform and reproduce in 3D,” said 3D Biomatrix CEO Laura Schrader.

"Our worldwide customers include researchers in academia performing cell biology, cancer and stem cell research as well as leading pharmaceutical companies who want to reduce the drug attrition rate by getting more relevant answers earlier in their research process along with the ability to perform high-content analysis and high-throughput screening,” concluded Schrader.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More Than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

3D Biomatrix Awarded Key Patent
3D Biomatrix announces issuance of U.S. Patent for its novel, easy-to-use, and cost-effective Perfecta3D® Hanging Drop Plate technology
Friday, December 12, 2014
3D Biomatrix and Cayman Chemical Partner
Companies have partnered to develop and supply a novel assay kit for measuring the viability of cells growing in three-dimensional (3D) spheroids.
Monday, November 25, 2013
Scientific News
Breaking Cell Barriers with Retractable Protein Nanoneedles
Adapting a bacterial structure, institute researchers have developed protein actuators that can mechanically puncture cells.
Gene Signature could Lead to a New Way of Diagnosing Lyme Disease
Lyme disease patients had distinctive gene signatures that persisted for at least three weeks, even after they had taken the antibiotics.
Retractable Protein Nanoneedles
The ability to control the transfer of molecules through cellular membranes is an important function in synthetic biology; a new study from researchers at Harvard’s Wyss Institute for Biologically Inspired Engineering and Harvard Medical School (HMS) introduces a novel mechanical method for controlling release of molecules inside cells.
Leukemia’s Surroundings Key to its Growth
Researchers at The University of Texas at Austin have discovered that a type of cancer found primarily in children can grow only when signaled to do so by other nearby cells that are noncancerous.
Common Cell Transformed into Master Heart Cell
By genetically reprogramming the most common type of cell in mammalian connective tissue, researchers at the University of Wisconsin—Madison have generated master heart cells — primitive progenitors that form the developing heart.
‘Smelling’ Prostate Cancer
A research team from the University of Liverpool and the University of the West of England (UWE Bristol) has reached an important milestone towards creating a urine diagnostic test for prostate cancer that could mean that invasive diagnostic procedures that men currently undergo eventually become a thing of the past.
Genetic Mutation that Prevents Diabetes Complications
The most significant complications of diabetes include diabetic retinal disease, or retinopathy, and diabetic kidney disease, or nephropathy. Both involve damaged capillaries.
A Crystal Clear View of Biomolecules
Fundamental discovery triggers paradigm shift in crystallography.
Could the Food we Eat Affect Our Genes?
Almost all of our genes may be influenced by the food we eat, according to new research.
NIH Seeks Research Applications to Study Zika in Pregnancy, Developing Fetus
Institute has announced that the new effort seeks to understand virus effect on reproduction and child development.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!