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IntegenX Launches New GlobalFiler® Express Cartridges for RapidHIT® System

Published: Tuesday, February 18, 2014
Last Updated: Tuesday, February 18, 2014
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IntegenX has completed the Developmental Validation of GlobalFiler Express reagents from Life Technologies on the RapidHIT System in accordance with SWGDAM guidelines.

IntegenX Inc. announced the launch of GlobalFiler® Express cartridges for the RapidHIT™ System, providing DNA profiles with 24-loci in less than two hours with less than five minutes hands-on time. 

The RapidHIT GlobalFiler Express cartridges contain Life Technologies’ NDIS-approved GlobalFiler Express Kit which has all DNA markers commonly used in most international databases, including all markers recommended for inclusion by the CODIS Core Loci Working Group. The RapidHIT GlobalFiler Express cartridges feature a flexible design, allowing operators to run from one to seven samples in a single run, as well as a room temperature cartridge storage protocol.

IntegenX completed the Developmental Validation of the GlobalFiler Express cartridges with the RapidHIT System for buccal swabs with a highly successful CODIS profile generation rate. Completion of Scientific Working Group for DNA Analysis Methods (SWGDAM) Developmental Validation is a key milestone necessary for the commercialization of human DNA identification systems in forensics, law enforcement, defense, homeland security, and intelligence community applications: the RapidHIT is the only Rapid DNA System to have met such a milestone.

In addition to Developmental Validation data for buccal swabs, IntegenX has generated data demonstrating the RapidHIT System readily analyzes samples routinely recovered from crime scenes, such as blood, saliva, and semen. These applications dramatically expand the utility of the RapidHIT System and provide a fast DNA-based crime scene investigation and rapid lead identification capability for the law enforcement, defense, and intelligence communities worldwide. Data will be presented at the 66th Annual AAFS meeting, February 17-22, Seattle, Washington.

“The combination of the extremely high discrimination power of the large GlobalFiler Express multiplex and the capability of an expedited sample-to-answer with RapidHIT DNA technology should be a powerful tool to extend the utility of DNA typing both outside and within the laboratory,” said Bruce Budowle, Ph.D., executive director of the Institute of Applied Genetics at the University of North Texas Health Science Center (UNTHSC).

“We’re thrilled at the full commercial global launch of the RapidHIT GlobalFiler Express cartridges, and the new flexible format that allows operators to decide how many samples to include per run. The Developmental Validation of the GlobalFiler Express cartridges under SWGDAM guidelines is an important milestone. Offering Life Technologies’ most advanced NDIS-approved chemistry on the RapidHIT will be of great value to the US and worldwide forensic communities,” commented Robert Schueren, president and chief executive officer of IntegenX.

“The superior quality of the data obtained from GlobalFiler Express kits has proven to be a transformative solution for forensic labs,” said Nadia Altomare, vice president and general manager, Human Identification, for Thermo Fisher Scientific. “Our partnership with IntegenX brings together the industry’s most powerful chemistry and the leading rapid platform to help forensic laboratories and law enforcement agencies solve and prevent crimes.”

The IntegenX RapidHIT System fully automates and integrates all steps necessary to generate a DNA profile in less than two hours. With less than five minutes of hands-on time, an operator can generate up to seven complete DNA profiles. RapidHIT System DNA profiles are completely compatible with standard databases that contain previously generated profiles from reference and crime scene sources. Combining ease of use and rapid turnaround time for DNA human identification will have a high impact toward ensuring the safety of our communities.


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