Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Fera Utilizes CPS Disc Centrifuge UHR Analyzer to Study ENPs

Published: Wednesday, February 19, 2014
Last Updated: Wednesday, February 19, 2014
Bookmark and Share
CPS Disc Centrifuge analyzer demonstrates excellent measurement repeatability.

Analytik reports on the work of the Food & Environmental Research Agency where they have carried out studies on engineered nanoparticles using various particle sizing techniques, notably differential centrifugal sedimentation analysis.

The Food and Environment Research Agency (Fera) is an Executive Agency of the Department for Environment, Food and Rural Affairs (Defra). One of its areas of responsibility is research and assurance. This service provides robust scientific evidence, rigorous analysis and professional advice to the Government, international organizations and the private sector.

Agnieszka Dudkiewicz worked as a member of Dr Qasim Chaudhry's team studying engineered nanoparticles (ENPs). Many analytical methods are available these days to measure ENPs based on different principles and produce different types of measurement. This means that particle size distributions measured by different methods cannot be compared unless ENPs are ideally spherical (because measurement principles assume spherical particles and/or instruments are calibrated using spheres).

For this reason, currently there are no ENP reference materials available with a broad size distribution. The aim of the Fera study was the development of a uniform measurement expression, which would allow comparison of measurement outputs from different techniques for ENPs with broad size distributions and non-spherical shape.

In the study, various techniques including Differential Centrifugal Sedimentation (DCS) along with Nanoparticle Tracking Analysis (NTA), Field Flow Fractionation with Inductively Coupled Plasma detection (FFF-ICP-MS), Electron Microscopy (EM) and Gas-phase Electrophoretic Mobility Molecular Analysis (GEMMA) were trialled.

Ms Dudkiewicz described why the group opted to use the CPS system for this program. "We chose DCS as one of the research techniques because of its superior resolution in terms of the measurement of particles with polymodal particle size distribution when compared to other techniques. The CPS Disc Centrifuge analyzer also demonstrated excellent measurement repeatability. We also thought it would be suitable for the measurement of non-spherical ENPs and making comparative measurements with other techniques because of the possibility of particle size correction using effective density. Literature evidence also showed that Differential Centrifugal Sedimentation might be one of the techniques giving an accurate particle size distribution for polydisperse samples. In cited studies, researchers showed that proportions of the particles in polymodal distribution measured by the CPS system were in best agreement with the expected dispersion. We also found that the CPS Disc Centrifuge analyzer was user friendly and did not require extensive sample preparation and run times."


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More Than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Analytik Now Represent Microfluidics Corporation in the UK and Ireland
Partnership with Microfluidics Corporation for distribution and support of their Microfluidizer® fluid processors.
Tuesday, December 16, 2014
Studying Historic Materials with a Vis-NIR Portable Spectrometer
Analytik have reported how the LabSpec portable spectrometer from PANalytical Boulder is being used in the world of heritage research.
Wednesday, June 11, 2014
Producing DNA and Protein Arrays for Research
Dr Stoevesandt use GeSiM Nano-Plotter system for the production of various protein arrays.
Wednesday, May 28, 2014
Portable NIR Spectroscopy System used to Study Dali Canvases
Analytik report on the use of the ASD LabSpec portable NIR spectroscopy system in the Centre for Sustainable Heritage at UCL.
Wednesday, October 30, 2013
Analytik in Partnership with Agilent Hosted Two Workshops
Company reports workshops on portable molecular spectroscopy techniques & instrumentation.
Thursday, August 09, 2012
Analytik in Partnership with Agilent Hosted Two Workshops
Company reports workshops on portable molecular spectroscopy techniques & instrumentation.
Wednesday, August 08, 2012
Analytik Adds Handheld FTIR to Portable Spectroscopy Portfolio
Analytik announces a new arrangement to become sole value added resellers in the UK and Ireland for Agilent Technologies' portable and handheld FTIR spectrometers.
Wednesday, February 29, 2012
Analytik Partners with World-Leading Data Analysis Software Vendor, CAMO Software, for the UK & Irish Markets
Analytik's Marketing Manager, Tom Greenwell, believes CAMO software will enhance the experience of Analytik's users.
Tuesday, January 31, 2012
SPE Training Courses for Pharmaceutcial Bioanalysis
This course focuses on ways to quickly and efficiently extract compounds from biological samples.
Monday, May 08, 2006
Solid Phase Extraction Training Courses
Analytik Ltd is offering a series of short courses in collaboration with Chrom Solutions Ltd.
Friday, April 07, 2006
NIR-Online® – On-line Near Infrared Spectroscopy
Analytik to distribute NIR-Online GmbH online near infrared spectroscopy instrumentation systems in the UK.
Monday, April 03, 2006
Scientific News
RNAi Screening Trends
Understand current trends and learn which application areas are expected to gain in popularity over the next few years.
Diagnostic Test Developed for Enterovirus D68
researchers at Washington University School of Medicine in St. Louis have developed a diagnostic test to quickly detect enterovirus D68 (EV-D68), a respiratory virus that caused unusually severe illness in children last year.
How a Kernel Got Naked and Corn Became King
Ten thousand years ago, a golden grain got naked, brought people together and grew to become one of the top agricultural commodities on the planet.
Sweet Revenge Against Superbugs
A special type of synthetic sugar could be the latest weapon in the fight against superbugs.
New Material Opens Possibilities for Super-Long-Acting Pills
A pH-responsive polymer gel could create swallow able devices, including capsules for ultra-long drug delivery.
How To Keep Your Rice Arsenic-Free
Researchers at Queen’s University Belfast have made a breakthrough in discovering how to lower worrying levels of arsenic in rice that is eaten all over the world.
New Tool For Investigating RNA Gone Awry
A new technology – called “Sticky-flares” – developed by nanomedicine experts at Northwestern University offers the first real-time method to track and observe the dynamics of RNA distribution as it is transported inside living cells.
Computer Model Could Explain how Simple Molecules Took First Step Toward Life
Two Brookhaven researchers developed theoretical model to explain the origins of self-replicating molecules.
New Tech Enables Epigenomic Analysis with a Mere 100 Cells
A new technology that will dramatically enhance investigations of epigenomes, the machinery that turns on and off genes and a very prominent field of study in diseases such as stem cell differentiation, inflammation and cancer has been developed by researchers at Virginia Tech.
Access Denied: Leukemia Thwarted by Cutting Off Link to Environmental Support
A new study reveals a protein’s critical – and previously unknown -- role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!