Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>News>This Article

DDC Medical, NIST to Commercialise Mouse Cell Line Authentication

Published: Wednesday, February 26, 2014
Last Updated: Wednesday, February 26, 2014
Bookmark and Share
DDC Medical announce the signing of a license agreement with NIST to commercialize mouse cell line authentication (M-CLA) using STR DNA technology.

According to Hughes P. Marshall D, Reid Y, et al. 2007 BioTechniques 43.575-586, it has been shown that over a third of cell lines used for biomedical research are contaminated or misidentified resulting in wasted resources, unreliable data, and irreproducible results.

Mouse cell lines are commonly used as model systems to study human diseases.  According to Dr.Michael Baird, the Chief Science Officer at DDC, “The addition of mouse cell line authentication is a major step in maintaining the efficacy of biomedical research using cell lines.  We are honored to work with NIST to bring this vitally important test to market.” 

The DDC Medical mouse cell line authentication test uses STR DNA analysis to characterize the mouse DNA.  The loci selected produce stable, robust results based on a tetranucleotide repeat, similar to the types of loci examined for human cell line authentication (H-CLA).  Other mouse cell line tests available use either dinucleotide repeat STR loci that are difficult to interpret, or large SNP arrays that are expensive and time consuming to perform.  The DDC Medical mouse cell line authentication test is inexpensive with a short turnaround time.

DDC Medical currently provides human cell line authentication and mycoplasma detection to academic researchers, biotech, and bio pharma customers.  Recent emphasis by scientific Journals to authenticate cell lines prior to publication has increased awareness of the issues of cell line contamination and misidentification.  Funding sources are also strongly recommending that appropriate quality controls be implemented to ensure cell line integrity.   In late 2013, the Prostate Cancer Foundation initiated requirements to authenticate cell lines used by the PCF’s grant recipients.

DDC’s CEO, Peter Vitulli stated, “With Dr. Baird’s direction, DDC Medical is honored to collaborate with NIST to address contaminated and misidentified mouse cell lines.”

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More Than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
High Throughput Mass Spectrometry-Based Screening Assay Trends
Dr John Comley provides an insight into HT MS-based screening with a focus on future user requirements and preferences.
Kitchen Utensils Can Spread Bacteria Between Foods
In a recent study researchers found that produce that contained bacteria would contaminate other produce items through the continued use of knives or graters—the bacteria would latch on to the utensils commonly found in consumers' homes and spread to the next item.
Exploring the Causes of Cancer
Queen's research to understand the regulation of a cell surface protein involved in cancer.
Safer, Faster Way To Remove Pollutants From Water
Using nanoparticles filled with enzymes proves more effective than current methods.
Drug May Prevent Life-Threatening Muscle Loss in Advanced Cancers
New data describes how an experimental drug can stop life-threatening muscle wasting (cachexia) associated with advanced cancers and restore muscle health.
Ancient Viral Molecules Essential for Human Development
Genetic material from ancient viral infections is critical to human development, according to researchers at the Stanford University School of Medicine.
Novel Tumor Treatment
In the first published results from a $386,000 National Cancer Institute grant awarded earlier this year, a paper by Scott Verbridge and Rafael Davalos has been published.
Speeding Up the Process of Making Vaccines
System uses a freeze-dry concept to develop "just-add-water" solution.
Chemical Design Made Easier
Rice University scientists prepare elusive organocatalysts for drug and fine chemical synthesis.
New Analysis Technique for Chiral Activity in Molecules
Professor Hyunwoo Kim of the Chemistry Department and his research team have developed a technique that can easily analyze the optical activity of charged compounds by using nuclear magnetic resonance (NMR) spectroscopy.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos