Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>News>This Article

DDC Medical, NIST to Commercialise Mouse Cell Line Authentication

Published: Wednesday, February 26, 2014
Last Updated: Wednesday, February 26, 2014
Bookmark and Share
DDC Medical announce the signing of a license agreement with NIST to commercialize mouse cell line authentication (M-CLA) using STR DNA technology.

According to Hughes P. Marshall D, Reid Y, et al. 2007 BioTechniques 43.575-586, it has been shown that over a third of cell lines used for biomedical research are contaminated or misidentified resulting in wasted resources, unreliable data, and irreproducible results.

Mouse cell lines are commonly used as model systems to study human diseases.  According to Dr.Michael Baird, the Chief Science Officer at DDC, “The addition of mouse cell line authentication is a major step in maintaining the efficacy of biomedical research using cell lines.  We are honored to work with NIST to bring this vitally important test to market.” 

The DDC Medical mouse cell line authentication test uses STR DNA analysis to characterize the mouse DNA.  The loci selected produce stable, robust results based on a tetranucleotide repeat, similar to the types of loci examined for human cell line authentication (H-CLA).  Other mouse cell line tests available use either dinucleotide repeat STR loci that are difficult to interpret, or large SNP arrays that are expensive and time consuming to perform.  The DDC Medical mouse cell line authentication test is inexpensive with a short turnaround time.

DDC Medical currently provides human cell line authentication and mycoplasma detection to academic researchers, biotech, and bio pharma customers.  Recent emphasis by scientific Journals to authenticate cell lines prior to publication has increased awareness of the issues of cell line contamination and misidentification.  Funding sources are also strongly recommending that appropriate quality controls be implemented to ensure cell line integrity.   In late 2013, the Prostate Cancer Foundation initiated requirements to authenticate cell lines used by the PCF’s grant recipients.

DDC’s CEO, Peter Vitulli stated, “With Dr. Baird’s direction, DDC Medical is honored to collaborate with NIST to address contaminated and misidentified mouse cell lines.”

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,600+ scientific posters on ePosters
  • More Than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
Researchers Develop Classification Model for Cancers Caused by KRAS
Most frequently mutated cancer gene help oncologists choose more effective cancer therapies.
Fixing Holes in the Heart Without Invasive Surgery
UV-light enabled catheter is a medical device which represents a major shift in how cardiac defects are repaired.
Chromosomal Chaos
Penn study forms basis for future precision medicine approaches for Sezary syndrome
Enzyme Malfunction May be Why Binge Drinking Can Lead to Alcoholism
A new study in mice shows that restoring the synthesis of a key brain chemical tied to inhibiting addictive behavior may help prevent alcohol cravings following binge drinking.
Key to Natural Detoxifier’s Reactivity Discovered
Results have implications for health, drug design and chemical synthesis.
New Treatment for Obesity Developed
Researchers at the University of Liverpool, working with a global healthcare company, have helped develop a new treatment for obesity.
New Protein Found in Immune Cells
Immunobiologists from the University of Freiburg discover Kidins220/ARMS in B cells and demonstrate its functions.
Will Brain Palpation Soon Be Possible?
Researchers have developed non-invasive brain imaging technique which provides the same information as physical palpation.
Shaking Up the Foundations of Epigenetics
Researchers at the Centre for Genomic Regulation (CRG) and the University of Barcelona (UB) published a study that challenges some of the current beliefs about epigenetics.
Groundbreaking Computer Program Diagnoses Cancer in Two Days
Researchers have combined genetics with computer science and created a new diagnostic technology can with 85 per cent certainty identify the source of the disease and thus target treatment and, ultimately, improve the prognosis for the patient.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos