Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Channel-Free Microfluidic Technology for Molecular Testing Developed

Published: Saturday, February 08, 2014
Last Updated: Thursday, February 27, 2014
Bookmark and Share
The Smart FilmCARD would be the first microfluidic device in the diagnostics industry with no channels included in its design.

Rheonix, Inc. has created a channel-free microfluidic device, the Rheonix Smart FilmCARD™. This breakthrough will significantly decrease the research, development and production costs of microfluidic solutions and allow sophisticated diagnostic tests to become more widely available. The Smart FilmCARD is capable of complex fluid manipulations with potential applications in research laboratories, genetic sequencing sample preparations and in vitro diagnostic (IVD) assays. 

The Smart FilmCARD is a groundbreaking evolution of Rheonix’s existing core technology, the Chemistry and Reagent Device (CARD®). The CARD runs samples through a fully integrated molecular assay without user intervention based upon Rheonix’s novel solvent lamination capabilities. Compared with the CARD technology, the Smart FilmCARD uses the deformed gasket wall to replace channels for fluidic network formation. The channel-free design permits controlled movement of fluids anywhere on the Smart FilmCARD while virtually eliminating dead-volume losses typical of channeled devices. Without channels, reagents can be packaged and stored easily on the device to allow more varied applications than are currently possible in the life sciences tools and IVD markets. 

“The capability to reliably package micro-liter volumes of reagents into a device and pump those reagents in a manner that is not limited by predefined fluid pathways opens Rheonix to diagnostic applications not previously envisioned, or possible,” said Peng Zhou, Ph.D., Rheonix chief scientific officer. “For the first time, we will be able to work with researchers and developers to design a device with the cost structure and function that enables subsidy-free adoption of advanced molecular technologies to facilitate widespread diagnosis of diseases such as drug-resistant tuberculosis, malaria, dengue fever, Chagas disease and other human afflictions that cause serious illness and death throughout the world.” 

The Smart FilmCARD enables Rheonix to address diverse market requirements that are too difficult to perform with existing systems, such as automated next-generation sequencing library sample preparation, low-cost infectious disease panel testing and point-of-care applications. It also enables Rheonix to serve markets requiring small-volume reagent management, onboard reagents and simpler testing procedures while dramatically lowering the complexity of manufacturing molecular devices. 

“Simply put, we see applications for this platform across the full spectrum of molecular analysis applications. This elegantly simple approach to fluidic handling has the ability to address market needs around the globe with functional utility in applications as diverse as next-generation sequencing preparations and point-of-care molecular diagnostics testing,” said Tony Eisenhut, Rheonix president. 

The Smart FilmCARD development efforts will continue within the newly formed Rheonix Innovation Center under the direction of Peng Zhou. Zhou holds 14 U.S. patents. “For a researcher, there is nothing more exciting than being given a blank canvas and the tools to create solutions for pressing problems. The Smart FilmCARD is this canvas, and we will explore a variety of applications free from constraints due to cost-of-goods-sold limitations,” Zhou said.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More Than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Rheonix to Pursue Rapid Zika Virus Diagnostic
Company to develop automated system for simultaneous Zika virus detection and confirmation.
Wednesday, April 20, 2016
Rheonix Raises $28.6 Million to Further Expand MDx Efforts
Company further expand the commercialization efforts of molecular testing platforms.
Friday, October 23, 2015
Rheonix Inc. Raises $28.6 Million
Rheonix Inc.raised $28.6 million to further expand the company’s commercialization efforts for its breakthrough molecular testing platforms, the Encompass MDx® and Encompass Optimum™.
Thursday, October 22, 2015
Rheonix Receives Patent for Molecular Diagnostic Testing Device
The company has been granted patent 9,132,398, “Integrated Microfluidic Device and Methods,” for the Rheonix CARD® cartridge, which enables assays to be performed on the company’s EncompassMDx® and Encompass Optimum™ instruments.
Wednesday, September 16, 2015
Scientific News
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.
One Step Closer to Precision Medicine for Chronic Lung Disease Sufferers
A study led by University of North Carolina at Chapel Hill, and National Jewish Health, has provided evidence of links between SNPs and known COPD blood protein biomarkers.
A Diversity of Genomes
New DNA from understudied groups reveals modern genetic variation, ancient population shifts.
“Sixth Sense” May Be More Than Just A Feeling
The NIH Study shows that two young patients with a mutation in the PIEZ02 have problems with touch and proprioception, or body awareness.
Gene Could Reduce Female Mosquitoes
Virginia Tech researchers have found a gene that can reduce female mosquitoes over many generations.
Biomolecular Manufacturing ‘On-the-Go’
Wyss Institute team unveils a low-cost, portable method to manufacture biomolecules for a wide range of vaccines, other therapies as well as diagnostics.
Improving Crop Efficiency with CRISPR
New study of CRISPR-Cas9 technology from Virginia Tech shows potential to improve crop efficiency.
Fighting Cancer with Sticky Nanoparticles
Treatment that uses bioadhesive nanoparticles drug carriers proved more effective than conventional treatments for certain cancers.
Stem Cell ‘Heart Patch’ Almost Perfected
Scientists aiming to perfect and test 3D "heart patches" in animal model, last hurdle before human patients.
Fighting Plant Pathogens with RNA
Researchers develop strategy that could lead to environmentally friendly fungicide to fight pathogens.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!