Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>News>This Article

Agilent Thought Leader Award Supports Metabolic Research

Published: Tuesday, April 22, 2014
Last Updated: Tuesday, April 22, 2014
Bookmark and Share
Princeton team developing LC/MS methods, bioinformatics tools for discovery of metabolic regulatory mechanisms.

Agilent announce that Joshua Rabinowitz, M.D, Ph.D., professor at Princeton University’s Department of Chemistry and the Lewis-Sigler Institute for Integrative Genomics, has received an Agilent Thought Leader Award to support his work on quantitative analysis of cellular metabolism.

Dr. Rabinowitz is a world-renowned scientist who has made seminal conceptual and methodological contributions to the metabolomics field. These include the development of isotopic labeling, sample preparation, data analysis, and information visualization techniques for liquid chromatography/mass spectrometry data. Together these techniques allow researchers to piece together static snapshots of metabolite levels provided by LC/MS into an understanding of dynamic metabolic activity in living systems. Dr. Rabinowitz has applied these tools to identify metabolic remodeling in infectious disease and cancer pathogenesis. The resulting understanding has led to new targets for therapeutic intervention.

“We are very happy to expand our work with Dr. Rabinowitz and his team to support their efforts developing quantitative proteomics methodologies and pan-omics studies of metabolism,” said John Fjeldsted, Agilent’s director of Mass Spectrometry Research and Development. “We believe this work will have a significant impact in many fundamental areas of research.”

The Agilent award will support Dr. Rabinowitz’s research on global cell metabolism and its regulation. He will make use of the quantitative capabilities of the Agilent 6550 MS-QTOF to generate protein stability information to supplement transcriptomics, proteomics, metabolomics, and metabolic flux data sets. From protein abundances and stabilities, he will be able to infer protein fluxes and thereby assemble an integrative understanding of how protein levels are regulated and how this ties into overall cellular metabolic activity.

“I am delighted to be working with Agilent, whose combined expertise in wet chemistry, instrumentation and software makes them an outstanding partner for my lab,” said Dr. Rabinowitz. “We share Agilent’s goal of enabling quantitative measurement of all key biomolecules, and of building computational tools that integrate such data to reveal new principles of living systems. Such tools hold the potential to revolutionize biomedical research.”

The Agilent Thought Leader Award promotes fundamental scientific advances by contributing financial support, products and expertise to the research of influential thought leaders in life sciences and chemical analysis. Information about previous award recipients is available at Agilent’s Thought Leader Program website.

The Lewis-Sigler Institute for Integrative Genomics
The Lewis-Sigler Institute for Integrative Genomics, housed in the Carl Icahn Laboratory at Princeton University, was established to innovate in research and teaching at the interface of modern biology and the more quantitative sciences. The Institute is the hub of the Center for Quantitative Biology, funded by the National Institute of General Medical Sciences, one branch of the National Institutes of Health.

Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More Than 5,100+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Agilent, Burning Rock Sign Agreement on Molecular Diagnostics
Companies collaborate in their aim to accelerate accurate diagnosis of cancer for patients in China.
Thursday, September 29, 2016
Impact of Emerging Contaminants in Our Water Supply
Emerging contaminants, any synthetic or naturally occurring chemical not commonly monitored in the environment, in our water supply are becoming of increasing concern due to their potential ecological and/or human health effects.
Friday, September 16, 2016
Agilent Technologies to Build New Facility in Colorado
Agilent buys 20 acres in Weld County to increase pharmaceutical manufacturing capacity.
Wednesday, August 10, 2016
Dako Announces CE Mark for Companion Diagnostic
Dako has announced the CE Mark certification for use of PD-L1, a companion diagnostic to Merck's anti-PD-1 immunotherapy Keytruda.
Thursday, August 04, 2016
Agilent to Acquire iLab Solutions
Companies have announced they have signed a definitive agreement under which Agilent will acquire substantially all of the assets of iLab, the market leader in cloud-based solutions for core laboratory management.
Wednesday, June 29, 2016
Agilent, Eurofins Genomics Collaborate
Agilent plans to offer custom components and an assembled plasmid service for Agilent’s SureVector next-generation cloning kits through a collaboration with Eurofins.
Monday, March 14, 2016
Best Practices for Breast Cancer Diagnosis
Agilent has published “Breast Cancer Diagnosis: Past, Present and Future,” a white paper on the use of immunohistochemistry in diagnosing and treating breast cancer.
Monday, March 14, 2016
Agilent Invests $80M in Lasergen
Company has announced that it has invested $80 million in Lasergen, with innovative next-generation sequencing technology for clinical applications.
Friday, March 11, 2016
Agilent Technologies Announces Early Access to Custom guideRNA for Functional Genomics
Company has announced a program that gives biologists conducting functional genomics research early access to a potential new resource.
Saturday, February 13, 2016
Agilent Technologies and 10x Genomics Announce Collaboration
Company has announced collaboration to develop a premium exome that provides a streamlined workflow for 10x Genomics'Chromium platform.
Friday, February 12, 2016
Agilent Wins Award for Innovation in LC
Dual-needle technology enhances speed, flexibility.
Thursday, January 28, 2016
Agilent Extends Agreement with PerkinElmer on Bioanalyzer Chips
PerkinElmer supplies chips for Agilent's popular 2100 Bioanalyzer system.
Thursday, January 21, 2016
Agilent Signs Agreement with Thermo Fisher Scientific
Agreement to exchange instrument controls to improve the productivity and user experience.
Thursday, November 12, 2015
Agilent Completes Acquisition of Seahorse Bioscience
Agilent has completed the acquisition of Seahorse Bioscience, a leader in providing instruments and assay kits for measuring cell metabolism and bioenergetics.
Tuesday, November 03, 2015
Agilent Recognizes Australian Genome Research Facility as Certified Service Provider
Nonprofit organization offers scientists access to leading-edge technologies.
Saturday, October 31, 2015
Scientific News
Integrated Omics Analysis
Studying multi-omics promises to give a more holistic picture of the organism and its place in its ecosystem, however despite the complexities involved those within the field are optimistic.
Unravelling the Role of Key Genes and DNA Methylation in Blood Cell Malignancies
Researchers from the University of Nebraska Medical Center have demonstrated the role of Dnmt3a in safeguarding normal haematopoiesis.
Salford Lung Study - The First Real World Clinical Trial
In this podcast, we learn about the Salford Lung Study and its potential to revolutionize the way we assess new drugs and treatments around the world.
Point of Care Diagnostics - A Cautious Revolution
Advances in molecular biology, coupled with the miniaturization and improved sensitivity of assays and devices in general, have enabled a new wave of point-of-care (POC) or “bedside” diagnostics.
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.
Structure of Primary Cannabinoid Receptor is Revealed
The findings provide key insights into how natural and synthetic cannabinoids including tetrahydrocannabinol —a primary chemical in marijuana—bind at the CB1 receptor to produce their effects.
Overlooked Molecules Could Revolutionise our Understanding of the Immune System
Researchers have discovered that around one third of all the epitopes displayed for scanning by the immune system are a type known as ‘spliced’ epitopes.
Illumina Contributes to ClinVar Database
The contribution includes variants of all classifications, from pathogenic to benign, identified during interpretation of whole genome sequences generated in the CLIA-certified, CAP-accredited Illumina Clinical Services Laboratory.
Agilent Presents Early Career Professor Award to Dr. Roeland Verhaak
JAX professor recognized for the development and implementation of workflows for the analysis of big-data from transcriptomics to next generation sequencing approaches.
NIH Study Determines Key Differences between Allergic and Non-Allergic Dust Mite Proteins
Researchers at NIH have uncovered factors that lead to the development of dust mite allergy and assist in the design of better allergy therapies.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,100+ scientific videos