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Agilent Introduces Cary 8454 UV Dissolution System

Published: Tuesday, May 06, 2014
Last Updated: Tuesday, May 06, 2014
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Next-generation diode array UV dissolution system for the pharmaceutical industry.

Agilent Technologies Inc. has introduced the Cary 8454 UV Dissolution System, which incorporates new Cary 8454 UV-Vis Spectrophotometer technology and enables researchers to sample the entire UV spectrum for fast, efficient diode array analysis.

The 8454 UV Dissolution System is available in several scalable solutions to support both online and offline dissolution analysis.

The 8454 UV Dissolution System is an ideal solution for both single and multicomponent products. The system is available in three configurations to support a variety of laboratory needs:

• Multicell-based single apparatus for dedicated flow-cell lines, eliminating cross-contamination and supporting simultaneous or sequential UV analysis.
• Valve-based single apparatus for sequential sampling, offering the most economical option with use of a single-flow cell line.
• Valve-based multi-apparatus, enhancing the productivity of up to four apparatus and supporting the testing of large amounts of samples.

The 8454 system uses Agilent's UV-ChemStation Dissolution Software, which seamlessly integrates with OpenLAB ECM. To complete an entire dissolution test and UV analysis, the UV-ChemStation software controls the spectrophotometer as well as Agilent and legacy Varian and VanKel dissolution apparatus, all in a 21 CFR Part 11-compliant environment.

"In addition to our UV scanning technologies, the next-generation 8454 UV Dissolution System reinforces Agilent's commitment to diode array UV detection," said Allan Little, Agilent's director of marketing, Dissolution Systems. "The system, with a history of more than 30 years of reliability, meets all the pharmacopeial requirements, and the latest UV-ChemStation software further enhances 21 CFR Part 11 compliance."


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