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Dako Launches Two Ready-to-Use Antibodies for Cancer Diagnosis

Published: Wednesday, May 07, 2014
Last Updated: Tuesday, May 06, 2014
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Company announces addition of Anti-CK 8/18 and Anti-TdT antibodies for routine diagnostic use.

Dako has announced the addition of two new antibodies, Anti-CK 8/18 and Anti-TdT, to the Dako portfolio of high-quality reagents, instruments and software.

Anti-CK 8/18 is the first rabbit monoclonal antibody cocktail for cytokeratin 8/18 (CK 8/18) available from a major pathology provider. It is used by pathologists to stain CK 8/18 in tissue samples and thereby help classify tumors of unknown origin. Keratins are one of the most potent epithelial differentiation and tumor markers in cancer diagnostics.

Anti-TdT, also a rabbit monoclonal antibody, is used to help classify lymphoma and leukemia by staining terminal deoxynucleotidyl transferase (TdT) in tissue samples. In immunohistochemistry, antibodies to TdT can be used to demonstrate the presence of pre-T and pre-B cells and multipotent hematopoietic stem cells that possess the antigen.

Both Anti-CK 8/18 and Anti-TdT provide excellent specificity and sensitivity and have been reviewed and accepted by key pathology experts. Both antibodies provide optimal staining results enabled by the FLEX Ready-to-Use Dako solutions.

FLEX Ready-to-Use is a plug-and-play solution consisting of pre-diluted antibodies, a visualization system, and optimized validated protocols developed in collaboration with leading pathology experts.

The protocols are developed to take into account pre-analytical variations and different ways of processing and handling tissue samples, ensuring optimal staining results for pathology labs.

"With the FLEX RTU solution, it takes less time for a lab to validate new antibodies for routine diagnostic use," said Hans Christian Pedersen, global product manager, Dako IHC reagents. "FLEX Ready-to-Use antibodies are helping labs get high-quality results from day one."

"We are pleased to add these two high-quality antibodies to our comprehensive offering to pathologists around the world," said Britt Meelby Jensen, vice president of Marketing and Pathology Sales in Agilent's Diagnostics and Genomics business. "One of our goals is to constantly establish new quality benchmarks within IHC reagents."

Both products are available from Dako now as 1.0 mL concentrates and 12 mL (60 tests) FLEX RTUs for Autostainer Link 48.

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