Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Owlstone Introduces UltraFAIMS for Improved Mass Spectrometry

Published: Monday, June 16, 2014
Last Updated: Thursday, June 12, 2014
Bookmark and Share
A low-cost accessory for mass spectrometers that provides an additional dimension of high-speed separation by ion mobility.

Owlstone Ltd announced the commercial launch of its UltraFAIMS series of products, developed to enhance mass spectrometry (MS) by quickly simplifying complex mass spectra, separating isobaric ions and reducing background. The new products were launched today at the 62nd ASMS Conference on Mass Spectrometry and Allied Topics, June 15th-19th 2014, Baltimore, MD.

UltraFAIMS is a miniaturized chip-based FAIMS (Field Asymmetric Ion Mobility Spectrometry) platform technology developed by Owlstone. UltraFAIMS can be interfaced with mass spectrometers to provide an additional in-source separation stage for isobaric analytes, protein and peptide charge states, large and small proteins, isomers and conformers. Miniaturizing the chip has allowed Owlstone to generate much higher field strengths than have been available in FAIMS systems up to now. This means that a greater range of analytes can be separated, at faster speeds, without compromising the system sensitivity. 

The newly-launched UltraFAIMS ion filters incorporate the miniaturized FAIMS chip, and can be retrofitted onto mass spectrometers. The low-cost modules have been shown to improve mass accuracy and detection limits, increase the level of quantitation and dynamic range, reduce background and provide additional real-time separation within LC peaks. Once installed, UltraFAIMS can be turned on to provide extra separation, or turned off to allow transmission of all species simultaneously – there is no need to remove it from the system when not in use. Its small size (height, width and depth ≈ 20cm) and straightforward interface mean it can easily be added to an established laboratory setup. 

Professor Colin Creaser, Head of the Centre for Analytical Science at Loughborough University, whose group has been working with a pre-production instrument, said: “Owlstone’s chip-based FAIMS system is very straightforward to use and has demonstrated potential for the analysis of small molecules, peptides and proteins. We are particularly excited about its ability to enhance high-throughput mass spectrometry applications by separating target ion responses from isobaric and isomeric ions.”

The product range includes:

• UltraFAIMS-A1, compatible with Agilent 6130/6150 (SQ), 6460 (QQQ), 6230 (TOF) and 6530/6540 (QTOF)
• UltraFAIMS-T1, compatible with Thermo Exactive Series & LTQ-Orbitrap
• UltraFAIMS-DK1 (developer kit), which is available for instrument developers or vendors who wish to interface with a mass spectrometer or source for which an off-the-shelf interface isn’t currently available


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More Than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Owlstone Medical Raises $7M to Commercialize Disease Breathalyzer
Investment will fund ongoing clinical trials in lung and colon cancer screening.
Wednesday, June 29, 2016
Scientific News
Point of Care Diagnostics - A Cautious Revolution
Advances in molecular biology, coupled with the miniaturization and improved sensitivity of assays and devices in general, have enabled a new wave of point-of-care (POC) or “bedside” diagnostics.
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.
One Step Closer to Precision Medicine for Chronic Lung Disease Sufferers
A study led by University of North Carolina at Chapel Hill, and National Jewish Health, has provided evidence of links between SNPs and known COPD blood protein biomarkers.
Charles River Acquires Agilux
Enhances Charles River’s early-stage capabilities in bioanalytical services.
Scientists Find Lethal Vulnerability in Treatment-Resistant Lung Cancer
The study describes how the drug Selinexor killed lung cancer cells and shrank tumors in mice when used against cancers driven by the aggressive and difficult-to-treat KRAS cancer gene.
How Baby’s Genes Influence Birth Weight And Later Life Disease
The large-scale study could help to target new ways of preventing and treating these diseases.
Genes Underlying Dogs’ Social Ability Revealed
The social ability of dogs is affected by genes that also seem to influence human behaviour, according to a new study from Linköping University in Sweden.
Drug to Treat Alcohol Use Disorder Shows Promise Among Drinkers With High Stress
The findings suggest that potential future studies with drugs targeting vasopressin blockade should focus on populations of people with AUD who also report high levels of stress.
C Dots Show Powerful Tumor Killing Effect
Nanoparticles known as Cornell dots, or C dots, have shown great promise as a therapeutic tool in the detection and treatment of cancer.
Faecal Bacteria Linked to Body Fat
Researchers at King’s College London have found a new link between the diversity of bacteria in human poo – known as the human faecal microbiome - and levels of abdominal body fat.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!