Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

New Mass Spectrometric Immunoassay Consumables Enable Large Biomolecule Analysis

Published: Monday, June 16, 2014
Last Updated: Monday, June 16, 2014
Bookmark and Share
The new functionalized pipette tips feature proprietary microcolumn technology designed to enable enhanced, reproducible target purification and reduce complexity in biological samples prior to liquid chromatography-mass spectrometry (LC-MS) protocols.

The new Thermo Scientific Mass Spectrometric Immunoassay (MSIA) pipette tips provides a robust technology designed to purify target proteins, peptides and therapeutic antibodies in a simplified way for downstream mass spectrometric analysis. Thermo Scientific MSIA pipette tips debut at the 62nd ASMS Conference on Mass Spectrometry and Allied Topics at the Holiday suite in the Hilton Baltimore Hotel. 

“As researchers use LC-MS to quantitate low abundance proteins and related variants, protein purification is critical to reduce the complexity of the sample and allow shorter LC gradients and ultimately maximize MS sensitivity,” said Clive Wingar, business director, liquid handling consumables, Thermo Fisher Scientific. “Our MSIA technology can uncover and quantify down to picomolar-levels of proteins, protein variants, and post-translational modifications with exceptional reproducibility. Testing more samples in less time with accurate results enables researchers to lead the way in biomarker discovery and analysis, biotherapeutics trials, and other critical discoveries.” 

The new MSIA consumables are suited for research applications and are available in a range of formats to support individual assay development needs, including: 

• Insulin: Simultaneous quantitative and qualitative analysis of endogenous insulin and exogenous insulin analogs purified from plasma, ideal for clinical research applications. 
• Streptavidin: Robust platform that immobilizes biotinylated affinity ligands to purify proteins and therapeutic antibodies for downstream MS analysis, ideal for biopharma applications. 
• Protein A, G, and A/G: Versatile option to bind and orientate a wide range of antibodies for targeted MS-assay development, ideal for antibody-related research applications. 
• Custom: Optimal affinity ligands are selected and covalently immobilized to the microcolumn surface, ideal for proven routine and high-throughput MS research applications. 

The MSIA consumables are an integral part of a MS-based workflow solution that includes automated liquid handling with the Thermo Scientific Versette Automated Liquid Handler and downstream sample analysis using MS systems, such as the Thermo Scientific TSQ Quantiva triple-stage quadrupole, Thermo Scientific Orbitrap Elite hybrid and Thermo Scientific Q Exactive mass spectrometers. 


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,900+ scientific posters on ePosters
  • More Than 5,300+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Thermo Fisher Acquires MTI-GlobalStem
The technology strengthens Thermo Fisher’s leadership in biosciences and provides scientists around the world with access to a wider array of advanced research products designed to help accelerate discovery using cell models.
Wednesday, November 30, 2016
Thermo Fisher Scientific Acquires MTI-GlobalStem
Thermo expands transfection and stem cell research arm by acquiring MTI-GlobalStem, specialists in cell transfection, neurobiology and stem cell research applications.
Wednesday, November 30, 2016
Thermo, Hamilton Storage Collaborate
Thermo and Hamilton Storage collaborate on new Thermo Scientific Decapper, giving users flexibility with a seamless switch between tube and rack types.
Wednesday, November 23, 2016
Thermo Fisher Submits PMA Application to FDA for Universal CDx Test
Universal CDx designed to support patient selection for specific therapies in non-small cell lung cancer and multiple drug development programs.
Tuesday, November 15, 2016
Thermo Completes $4.2B FEI Acquisition
Business will become part of Thermo Fisher’s Analytical Instruments Segment.
Thursday, September 22, 2016
Thermo Fisher Opens New Clinical Services Facility in Korea
The new site will provide local, regional and global pharmaceutical and biotech companies with a one-stop service for clinical supplies.
Thursday, September 15, 2016
Thermo Fisher, HBM Collaborate
Collaboration aims to support molecular diagnostics development in China.
Friday, July 29, 2016
Thermo, DuPont Extend Food Safety Agreement
Thermo Fisher scientific and DuPont Nutrition & Health extend BAX System Q7 Distribution agreement in Western Europe for an additional three years.
Thursday, July 14, 2016
Thermo Fisher, Cytonome/ST Announce Partnership
Partnership aims to focus on the development of a new line of flow cytometry cell sorting platforms.
Tuesday, June 28, 2016
Thermo Recognizes Tandem Mass Tag Grant Award Winners at ASMS 2016
International competition rewards three top proteomics researchers for outstanding innovation and impact.
Thursday, June 09, 2016
Native Mobile Capabilities Added to Thermo SampleManager
One of world’s most widely deployed LIMS continues to add functionality that modern labs require.
Monday, March 14, 2016
Thermo, Children’s Hospital Los Angeles Partner
Children’s Hospital Los Angeles (CHLA) and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research. The assay would be CHLA’s first NGS panel designed to target biomarkers associated with childhood cancers.
Friday, February 19, 2016
Thermo Scientific Gemini Handheld Chemical Analyzer Wins R&D 100 Award
Two-in-one portable device also earns Editor’s Choice in Analytical/Test category for 2015 by R&D Magazine.
Thursday, November 26, 2015
Thermo Scientific Signs Agreement with Novartis, Pfizer
Universal test designed for non-small cell lung cancer supports multiple drug development programs.
Thursday, November 26, 2015
Thermo Scientific Opens New GMP Clinical Services Facility in Singapore
New regional BioPharma Services hub offers larger operational space and advanced equipment to meet increasing clinical supply needs for pharma and biotech customers.
Saturday, November 21, 2015
Scientific News
Big Genetics in BC: The American Society for Human Genetics 2016 Meeting
Themes at this year's meeting ranged from the verification, validation, and sharing of data, to the translation of laboratory findings into actionable clinical results.
Stem Cells in Drug Discovery
Potential Source of Unlimited Human Test Cells, but Roadblocks Remain.
Cancer Genetics: Key to Diagnosis, Therapy
When applied judiciously, cancer genetics directs caregivers to the right drug at the right time, while sparing patients of unnecessary or harmful treatments.
BGI Sequences Gingko Tree, Revealing Large, Highly Repetitive Genome
Researchers at BGI have sequenced the more than 10-gigabase ginkgo genome to find a high number of repetitive sequences as well as a number of gene clusters that appear to be involved in defense mechanisms.
Survey of New York City Soil Uncovers Medicine-Making Microbes
Microbes have long been an invaluable source of new drugs. And to find more, we may have to look no further than the ground beneath our feet.
Accelerating the Detection of Foodborne Bacterial Outbreaks
The speed of diagnosis of foodborne bacterial outbreaks could be improved by a new technique developed by researchers at the Georgia Institute of Technology.
Making Personalized Medicine a Reality
Groundbreaking technique developed at McMaster University is helping to pave the way for advances in personalized medicine.
Scientists Identify Unique Genomic Features in Testicular Cancer
The findings may shed light on factors in other cancers that influence their sensitivity to chemotherapy.
Top 10 Life Science Innovations of 2016
2016 has seen the release of some truly innovative products. To help you digest these developments, The Scientist have listed their top picks for the year.
BioCision Forms MedCision
The new company will focus on technologies for the management and automation of vital clinical processes.
Scroll Up
Scroll Down
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,300+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!