Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Leti and Akrivis Develop Nanomedicine Platform for High Payload Targeted Drug Delivery

Published: Saturday, June 21, 2014
Last Updated: Friday, June 20, 2014
Bookmark and Share
New theranostic platform will combine ultrasensitive detection, high payloads and more efficient cell targeting.

CEA-Leti and Akrivis Technologies, LLC have announced their collaboration to develop an extremely adaptable, efficient and highly targeted drug delivery platform for chemotherapy and other treatments that require a high concentration of powerful drugs to be delivered precisely to targeted cells.

The new platform will be based on Akrivis Technologies’ proprietary Z–TECT™ technology that targets and detects unusually low levels of proteins and molecular targets and Leti’s Lipidot® nanovector delivery capability.

Developed by Akrivis Technologies, LLC, a biopharmaceutical company based in Cambridge, Mass. USA, Z–TECT™ is a unique technology platform that combines nanotechnology, molecular detection and immunology to provide high sensitivity and detection levels across multiple immunoassays and other assay formats, from colorimetric to fluorescent detection in vitro and imaging in vivo.

Developed by Leti and introduced for commercial uses in 2011, the Lipidot® technology is a versatile nano-delivery platform based on very small droplets of oil that encapsulate and carry drugs, fluorescent imaging agents or any other lipophilic payload to targeted cells for diagnosis or treatment.

By combining their delivery and targeting platforms, Leti and Akrivis intend to develop a new, more efficient and safer platform to deliver high payloads specifically to targeted cells. The resulting targeted nanoparticles will be optimized in a first phase for research and pre-clinical in vitro and in vivo applications. Then, in a second phase, they will be further developed clinically for in vitro diagnostics, in vivo imaging and targeted therapy.

“The new targeted nanoparticles jointly developed by Leti and Akrivis Technologies will dramatically improve the effectiveness of both diagnosis and treatment of diseases and reduce dangerous or unpleasant side effects,” said Patrick Boisseau, head of Leti’s nanomedicine program and chairman of the European Technology Platform – Nanomedicine (ETPN). “While specifically designed to meet the needs of pharmaceutical and biotech companies, the new platform will be customizable for other end-user applications such as diagnostics and theranostics.”

“Detecting disease earlier and delivering the precise drug dosage at the right place at the right moment are major steps towards improving patient diagnosis and treatment as well as controlling healthcare costs,” said Joel Berniac, CEO of Akrivis Technologies. “Akrivis and Leti have highly complementary nanomed technology platforms that will come together and offer physicians powerful new options for diagnosis and treatment.”

Supported by AEPI, the Grenoble-Isère economic development agency, Akrivis Technologies and Leti created a joint lab, which was launched on June 2.

“Leti’s collaboration with Akrivis Technologies underscores Grenoble’s strengths as a center for nanomedicine R&D and we are very pleased that they chose Leti and Grenoble for this exciting research and development project,” said Joëlle Seux, AEPI director.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,100+ scientific posters on ePosters
  • More Than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Leti and Diabeloop Project Aims at Developing Artificial Pancreas
Artificial pancreas will automatically deliver the appropriate dose of insulin to patients.
Saturday, July 25, 2015
Leti Announces Launch of First European Nanomedicine Characterization Laboratory
Project combines expertise of 9 partners in 8 countries to foster nanomedicine innovation and facilitate regulatory approval.
Tuesday, July 07, 2015
Eveon, Leti Mark Milestone in Fabrication of Smart Bolus-type Micro-pump
Both Companies announces the demonstration of liquid-pumping for smart drug delivery.
Friday, March 14, 2014
Leti Announces Project to Develop New Fingerprint Technology
Ultra-high resolution sensing uses vertical piezoelectric nanowire matrices to reconstruct the smallest features of human fingerprints.
Tuesday, February 18, 2014
PIEZOMAT Project Targets New Fingerprint Technology
Ultra-high resolution sensing uses vertical piezoelectric nanowire matrices to reconstruct the smallest features of human fingerprints.
Thursday, February 13, 2014
Leti Announces MEMS Research Collaboration with OMRON
Leti’s first collaboration with a Japanese MEMS producer.
Monday, December 09, 2013
CEA-Leti Signs Agreement with Qualcomm
Agreement to assess Leti’s sequential 3D technology.
Monday, December 09, 2013
Alim-Louis Benabid Honored by U.S. Research Institute
Benabid has received the Jay Van Andel Award for Outstanding Achievement in Parkinson’s Disease Research.
Friday, October 11, 2013
CEA-Leti Announces €1 Million Funding
bpifrance (ex OSEO) awarded grant to speed preclinical development of cancer-detecting nanoparticles.
Thursday, July 04, 2013
Patrick Boisseau Elected Chairman of the ETPN
Program will focus on building a structure that speeds innovations’ time to market and patients, while keeping Europe’s nanomed IP at home.
Monday, March 25, 2013
Attolight and Leti Launch Joint-Development Program
Program to extend applications for Company’s cathodoluminescence technology.
Monday, October 29, 2012
CEA-Leti and 7 Partners to Study Ways to Improve Treatment of Inflammatory Bowel Disease
Goal is to develop nanocarrier for targeted delivery of corticosteroids and immunosuppressants.
Thursday, April 14, 2011
Scientific News
The Rise of 3D Cell Culture and in vitro Model Systems for Drug Discovery and Toxicology
An overview of the current technology and the challenges and benefits over 2D cell culture models plus some of the latest advances relating to human health research.
New NIH-EPA Research Centers to Study Environmental Health Disparities
Scientists will partner with community organizations to study these concerns and develop culturally appropriate ways to reduce exposure to harmful environmental conditions.
Structure of Essential Digestive Enzyme Uncovered
Using a powerful combination of techniques from biophysics to mathematics, researchers have revealed new insights into the mechanism of a liver enzyme that is critical for human health.
Air Pollution Linked to Heart Disease
10-year project revealed air pollutants accelerate plaque build-up in arteries to the heart.
Getting a Better Look at How HIV Infects and Takes Over its Host Cells
A new approach, developed by a team of researchers led by The Rockefeller University and The Aaron Diamond AIDS Research Center (ADARC), offers an unprecedented view of how a virus infects and appropriates a host cell, step by step.
Following Tricky Triclosan
Antibacterial product flows through streams, crops.
Vitamin A May Help Improve Pancreatic Cancer Chemotherapy
The addition of high doses of a form of vitamin A could help make chemotherapy more successful in treating pancreatic cancer, according to an early study by Queen Mary University of London (QMUL).
Poverty Marks a Gene, Predicting Depression
New study of high-risk teens reveals a biological pathway for depression.
World’s Largest Coral Gene Database
‘Genetic toolkit’ will help shed light on which species survive climate change.
A Boost for Regenerative Medicine
Growing tissues and organs in the lab for transplantation into patients could become easier after scientists discovered an effective way to produce three-dimensional networks of blood vessels, vital for tissue survival yet a current stumbling block in regenerative medicine.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,100+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!