Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

BioDiscovery Awarded National Institutes of Health SBIR Grant

Published: Thursday, July 10, 2014
Last Updated: Wednesday, July 09, 2014
Bookmark and Share
SBIR Phase I grant to improve the copy number variation data from TCGA.

BioDiscovery, Inc. has announced the award of a Small Business Innovation Research (SBIR) Phase I grant from the National Institute of Health to improve the copy number variation (CNV) data from The Cancer Genome Atlas (TCGA), and has selected Huntsman Cancer Institute (HCI) at the University of Utah to assist in developing and validating the new product.

The commercial release of the improved TCGA copy number and sequence variant data will let researchers make further discoveries into tumorigenesis and disease progression and provide a meaningful validation set for internal studies.

“Our techniques for analyzing CNVs from raw data is unique and has proven highly effective, being used and cited in hundreds of publications.” says Soheil Shams, Ph.D., BioDiscovery’s Chief Scientific Officer. “We are applying methods, algorithms, and best practices learned from our experiences in clinical pathology settings to TCGA data. It’s a painstaking process, but the result will be the highest-fidelity CNV data from TCGA, and will integrate with our analysis platform to let researches quickly access and interrogate this database.”

“Copy number aberrations have been established as important drivers of many types of cancer, and as distinct from tumor classes driven primarily by somatic mutations,” says Louis Culot, Vice President of Marketing and Business Development at BioDiscovery.

Culot continued, “The NIH has recognized this, along with BioDiscovery’s unique expertise in CNV data analysis in the issue of this award. We are pleased to begin this work and expect it to have significant impact on further understanding of cancer genetics."

Joshua Schiffman, M.D., medical director of the High Risk Pediatric Cancer Clinic at Huntsman Cancer Institute (HCI) and associate professor of pediatrics at the University of Utah will be the lead investigator on the HCI arm of the project.

“The TCGA project, funded by NIH, has amazing potential but has proven challenging to unlock due to the processing of CNV information and difficulty in data access and analysis,” says Schiffman. “At HCI, we will work with the BioDiscovery team to help test and validate their approach to improved interaction with TCGA data sets. Results from these efforts will further our understanding of many types of cancer and hopefully lead to improved clinical care for patients.”

As part of the SBIR grant, Schiffman will work with BioDiscovery to demonstrate the clinical utility and translational impact of the TCGA data.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More Than 4,600+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

N-of-One and BioDiscovery Partner
Partnership equips laboratories and oncologists with a foundation for genomic data analysis through to therapeutic options.
Tuesday, March 25, 2014
BioDiscovery Initiates Software Donation Program to Benefit Pediatric Research
Company to donate up to $100,000 worth of software licenses per year to eligible scientists working in pediatric research.
Monday, January 07, 2013
BioDiscovery and AGRE Enter into a Co-Promotion Agreement
Agreement allows AGRE to provide copy number and allelic event data to its research users.
Wednesday, September 19, 2012
Cancer Centers Renew and Expand BioDiscovery’s Nexus Copy Number Software Licenses
BioDiscovery announces a number of license renewals and expansions of its Nexus Copy Number product at leading cancer research centers.
Wednesday, December 16, 2009
Fox Chase Cancer Center Adopts Nexus Copy Number and Nexus Expression
The center's Keystone Program in Blood Cell Development and Cancer gains a site license for two bioinformatics software programs from BioDiscovery.
Wednesday, February 11, 2009
BioDiscovery Granted its 7th U.S. Patent for Microarray Image Analysis
The patent covers the fundamental step of quantifying spots in microarray images.
Friday, January 27, 2006
United Bioinformatica Inc. to distribute BioDiscovery products to Canadian market

Thursday, April 17, 2003
BioDiscovery Inc. and Genops Bioinformatics Inc. Collaboration

Thursday, February 27, 2003
BioDiscovery and Azign Bioscience in silico Collaboration

Tuesday, October 29, 2002
BioDiscovery Distribution Agreement With Sigma-Genosys

Wednesday, July 24, 2002
BioDiscovery Inc. and Genops Bioinformatics Inc. Collaboration

Wednesday, February 27, 2002
Scientific News
Platelets are the Pathfinders for Leukocyte Extravasation During Inflammation
Findings from the study could help in the prevention and treatment of inflammatory pathologies.
ASMS 2016: Targeting Mass Spectrometry Tools for the Masses
The expanding application range of MS in life sciences, food, energy, and health sciences research was highlighted at this year's ASMS meeting in San Antonio, Texas.
Benchtop Automation Trends
Gain a better understanding of current interest in and future deployment of benchtop automated systems.
Manufactured Stem Cells to Advance Clinical Research
Clinical-grade cell line will enable development of new therapies and accelerate early-stage clinical research.
Dengue Virus Exposure May Amplify Zika Infection
Researchers at Imperial College London have found that the previous exposure to the dengue virus may increase the potency of Zika infection.
Gender Determination in Forensic Investigations
This study investigated the effectiveness of lip print analysis as a tool in gender determination.
Identifying Novel Types of Forensic Markers in Degraded DNA
Scientists have tried to verify the nucleosome protection hypothesis by discovering STRs within nucleosome core regions, using whole genome sequencing.
Proteins in Blood of Heart Disease Patients May Predict Adverse Events
Nine-protein test shown superior to conventional assessments of risk.
Higher Frequency of Huntington's Disease Mutations Discovered
University of Aberdeen study shows that the gene change that causes Huntington's disease is much more common than previously thought.
Starving Stem Cells May Enable Scientists To Build Better Blood Vessels
Researchers from the University of Illinois at Chicago College of Medicine have uncovered how changes in metabolism of human embryonic stem cells help coax them to mature into specific cell types — and may improve their function in engineered organs or tissues.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,600+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!