Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>News>This Article

BGI, University of Edinburgh Partner to Synthesize Synthetic Yeast Chromosome

Published: Friday, July 11, 2014
Last Updated: Friday, July 11, 2014
Bookmark and Share
Leading UK and Chinese research institutes have signed a longstanding research collaboration in the area of synthetic biology.

BGI and the University of Edinburgh have signed a collaboration agreement to pursue an ambitious synthetic biology “construction” project worth up to £1Million. The two institutes will team up to synthesize synthetic yeast chromosome VII in the Edinburgh Genome Foundry, recently funded by the UK’s Biotechnology and Biological Sciences Research Council and co-directed by Prof. Susan Rosser and Dr. Patrick Yizhi Cai.

Synthetic biology is a new emerging discipline, which is motivated by advances in molecular cell sciences, systems biology and the advent of two foundational technologies - DNA sequencing and DNA synthesis. The purpose of synthetic biology is to design synthetic biological systems by utilizing systematically engineered micro-organisms for the production of biofuels and drugs, providing a unique opportunity for researchers to study many profound life science questions and generate vital industrial applications.

Faculty members from Centre for Synthetic and Systems Biology (SynthSys) at the University of Edinburgh and at BGI will work together on synthesizing chromosome VII as part of the International Synthetic Yeast Project (Sc2.0).The Sc2.0 PROJECT, initiated by Johns Hopkins University School of Medicine, is the first synthetic eukaryotic genome project. The goal is to recreate the chromosome of yeast, a widely applied industrial microbe, so that it can be manipulated for useful purposes. The two parties will join forces to create an internationally competitive and innovative research team in the field of synthetic biology and work towards a breakthrough in the technology of artificially constructed yeast genome. In the collaboration agreement, the two parties will work towards gaining strategic advantages in automated synthesis of genomes, meeting the demands for cultivating new synthetic biology industries. Synthesized chromosome VII genome’s success various functions will be developed to be widely used in the production of chemicals, energy and food to maintain and enhance human health and the environment.

Dr Patrick Cai, a Chancellor’s Fellow at the University of Edinburgh, is leading the Sc2.0 project at Edinburgh and Yue Shen, BGI’s Synthetic Biology Unit leader, is currently studying for a PhD in Dr. Cai’s lab. Both institutes will benefit from this working relationship to accelerate the research of synthetic yeast.

The University of Edinburgh and BGI signed a memorandum of understanding with the aim to enhance collaborations between three genomics facilities in Edinburgh and BGI earlier this year. This is not the only collaboration between the University of Edinburgh and a Chinese Institute. In June 2014, the University signed a Memorandum of Understanding with Tianjin University around research and teaching in synthetic and systems biology.

Professor Peter Swain, Director of SynthSys says, “As in the UK, synthetic biology is a key area of investment for China and there is a substantial interest in collaboration and knowledge exchange that we are keen to participate in. We are thrilled to be working with the genomics giant BGI on such a landmark project in synthetic biology. ”

"Synthetic biology is a new emerging research field, which provides a unique opportunity for researchers to answer many fundamental questions in the life sciences.. When biological researchers are transitioning from the DNA sequence of an organism to a synthetic genome, researchers will face more challenges and opportunities with synthetic biology," stated Professor Huanming Yang, Chairman of BGI.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More Than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

BGI, Imperial and Waters Sign Translational Medicine Agreement
The collaboration brings together three of the leading scientific groups in the field of translational medicine.
Monday, September 15, 2014
BGI and The Vancouver Prostate Centre Partner
Partnership announced to create joint research laboratory for advancement of translational cancer research.
Friday, September 12, 2014
BGI's NGS Products Receive CFDA Approval
These are the first next generation sequencing diagnostic products approved by CFDA.
Thursday, July 03, 2014
Scientific News
High Throughput Mass Spectrometry-Based Screening Assay Trends
Dr John Comley provides an insight into HT MS-based screening with a focus on future user requirements and preferences.
How a Genetic Locus Protects Adult Blood-Forming Stem Cells
Mammalian imprinted Gtl2 protects adult hematopoietic stem cells by restricting metabolic activity in the cells' mitochondria.
Genetic Basis of Fatal Flu Side Effect Discovered
A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a recent study.
New Tech Vastly Improves CRISPR/Cas9 Accuracy
A new CRISPR/Cas9 technology developed by scientists at UMass Medical School is precise enough to surgically edit DNA at nearly any genomic location, while avoiding potentially harmful off-target changes typically seen in standard CRISPR gene editing techniques.
The MaxSignal Colistin ELISA Test Kit from Bioo Scientific
Kit can help prevent the antibiotic apocalypse by keeping last resort drugs out of the food supply.
"Good" Mozzie Virus Might Hold Key to Fighting Human Disease
Australian scientists have discovered a new virus carried by one of the country’s most common pest mosquitoes.
Non-Disease Proteins Kill Brain Cells
Scientists at the forefront of cutting-edge research into neurodegenerative diseases such as Alzheimer’s and Parkinson’s have shown that the mere presence of protein aggregates may be as important as their form and identity in inducing cell death in brain tissue.
Closing the Loop on an HIV Escape Mechanism
Research team finds that protein motions regulate virus infectivity.
New Class of RNA Tumor Suppressors Identified
Two short, “housekeeping” RNA molecules block cancer growth by binding to an important cancer-associated protein called KRAS. More than a quarter of all human cancers are missing these RNAs.
Potential Treatment for Life-Threatening Viral Infections Revealed
The findings point to new therapies for Dengue, West Nile and Ebola.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos