ZEISS ELYRA P.1 with 3D-PALM has been selected by the expert judges and editors of R&D Magazine as a recipient of a 2014 R&D 100 Award. The patented exclusive PALM technology of ZEISS ELYRA P.1 is regarded as one of 100 most significant high-technology products introduced in the past year.
As its name suggests, the 3D-PALM module enables superresolution photoactivated localization microscopy (PALM) in 3D. With ELYRA P.1 and 3D-PALM, researchers can capture highly resolved structures in 3D using photo-switchable proteins, while treating the sample so gently it stays fit for long-term observation.
Detection with an effective resolution down to 20 nm shows substructures and patterns where conventional light microscopy will simply show co-localization.
The technology has been supported by the Federal Ministry of Education and Research (German abbreviation: BMBF) as part of the project "Optical Technologies (biophotonics)".
The R&D 100 Awards celebrate the year's top technology products in the fields of new materials, chemical research, biomedical products and high-energy physics.
The winners come from the areas of industry, science, private research institutes and government laboratories. Since 2002, ZEISS has won one of the renowned awards every year.