Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

ZEISS Introduces LSM 880 with Airyscan

Published: Friday, August 01, 2014
Last Updated: Friday, August 01, 2014
Bookmark and Share
New confocal technology enables fast and sensitive super resolution microscopy.

ZEISS is introducing LSM 880 with Airyscan. The new confocal laser scanning microscope offers high sensitivity, enhanced resolution in x, y and z, and high image-acquisition speed in one system.

Sensitivity, Resolution, and Speed

Surveys results reveal that confocal imaging would benefit the most from increased sensitivity, resolution, and speed. Airyscan extends exactly those parameters. Users achieve a 1.7× higher resolution in all spatial dimensions, 140 nm laterally and 400 nm axially. The improved sensitivity leads to better image quality and increased speed. The whole imaging process is possible with standard sample preparation and labeling protocols.

The Airyscan Principle

A classic confocal microscope illuminates one spot on the sample to detect the emitted fluorescence signal. Out-of-focus emission light is rejected at a pinhole, the size of which determines how much of the Airy disk reaches the detector. Users can increase the resolution by making the pinhole smaller, but the signal-to-noise ratio drops significantly, since less valuable emission light is passing through. With Airyscan, ZEISS introduces a new concept. Instead of detecting signals with a single point detector, a multichannel area detector with 32 elements collects all the light from an Airy disk simultaneously. Hereby, each detector element functions as a single, very small pinhole. Knowing the beam path and the spatial distribution of each Airy disk enables very light-efficient imaging: researchers can now use all of the photons that the objective collected.

Quantitative Imaging and Improved Productivity

LSM 880 lets the user take full advantage of large fields of view and the highest speed of any linear scanning confocal microscope at an unsurpassed image quality. Designed for optimized productivity, LSM 880 identifies and localizes biological molecules of interest even in the most challenging specimens. To investigate subcellular structures at a new level of detail, the system provides the speed to monitor these molecules and their interactions in space and time while minimizing the input of light.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,000+ scientific posters on ePosters
  • More Than 4,400+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

50 Years of Scanning Electron Microscopy from ZEISS
ZEISS celebrates the birth of the first commercial scanning electron microscope in 1965.
Saturday, August 08, 2015
ZEISS and UC Berkeley Launch Public-Private Partnership
Microscopy tools optimized for use with emerging neurotechnologies provided for researchers.
Saturday, June 13, 2015
ZEISS Announces Partnership with ECR Engines
Providing analytical microscopes for NASCAR Engine Producer.
Saturday, April 04, 2015
Bessel Beam Plane Illumination Microscopy Enables Fast 3D Volume Imaging
ZEISS and the Janelia Research Campus sign an exclusive license agreement for commercialization.
Tuesday, September 16, 2014
ZEISS Acquires Xradia
X-ray microscopy solutions close the gap between light and electron microscopy.
Friday, July 19, 2013
New in ZEISS Online Campus: Spectral Imaging and Fluorescence Proteins
Fluorescence microscopy training course on the Internet
Friday, October 23, 2009
Scientific News
Releasing Cancer Cells for Better Analysis
A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Releasing Cancer Cells for Better Analysis
A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Apricot Kernels Pose Risk of Cyanide Poisoning
Eating more than three small raw apricot kernels, or less than half of one large kernel, in a serving can exceed safe levels. Toddlers consuming even one small apricot kernel risk being over the safe level.
Cell Transplant Treats Parkinson’s in Mice
A University of Wisconsin—Madison neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell.
Understanding Female HIV Transmission
Glowing virus maps points of entry through entire female reproductive tract for first time.
Genetic Markers Influence Addiction
Differences in vulnerability to cocaine addiction and relapse linked to both inherited traits and epigenetics, U-M researchers find.
Lab-on-a-Chip for Detecting Glucose
By integrating microfluidic chips with fiber optic biosensors, researchers in China are creating ultrasensitive lab-on-a-chip devices to detect glucose levels.
A lncRNA Regulates Repair of DNA Breaks in Breast Cancer Cells
Findings give "new insight" into biology of tough-to-treat breast cancer.
COPD Linked to Increased Bacterial Invasion
Persistent inflammation in COPD may result from a defect in the immune system that allows airway bacteria to invade deeper into the lung.
Detection of HPV in First-Void Urine
Similar sensitivity of HPV test on first void urine sample compared to cervical smear.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,400+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!