Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Expert Develops Nanoparticle Drug Delivery Method to Replace Eyedrops

Published: Friday, October 06, 2006
Last Updated: Friday, October 06, 2006
Bookmark and Share
The method uses biodegradable polymer nanoparticles to administer drugs to the eye.

Dr John Tsibouklis at the University of Portsmouth has announced that he has developed a nanoparticle drug delivery method, which uses biodegradable polymer nanoparticles to administer drugs to the eye.

Dr Tsibouklis said biodegradable polymers can be combined with drugs in such a way that the drug is released into the eye in a careful and controlled manner. The drug would have to be placed into the eye just once.

"The drug's release can be timed so it is constant, cyclic or triggered by an environmental or chemical signal, and the drug delivering polymer can be broken down naturally by the body when it is no longer needed," Dr Tsibouklis said.

People with eye conditions who use eye drops regularly would benefit from the biodegradable polymer drug delivery method.

Eye drops have many disadvantages- two main ones being the need to administer drops regularly and low ocular bioavailability (too little of the drug is getting to areas of the eye most in need).

The common alternative option to eye drops, ophthalmic inserts, achieve sustained drug delivery but suffer from limitations as- they are difficult to insert, easy to misapply and are expensive to manufacture.

Dr Tsibouklis said that the drug delivery systems hold significant promise for the pharmaceutical industry.

He describes the drug delivery systems in a paper, titled 'Polymeric materials for ophthalmic drug delivery: trends and perspectives' published in the Journal of Materials Chemistry.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,000+ scientific posters on ePosters
  • More Than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
The Rise of 3D Cell Culture and in vitro Model Systems for Drug Discovery and Toxicology
An overview of the current technology and the challenges and benefits over 2D cell culture models plus some of the latest advances relating to human health research.
World’s Largest Coral Gene Database
‘Genetic toolkit’ will help shed light on which species survive climate change.
A Boost for Regenerative Medicine
Growing tissues and organs in the lab for transplantation into patients could become easier after scientists discovered an effective way to produce three-dimensional networks of blood vessels, vital for tissue survival yet a current stumbling block in regenerative medicine.
Breast Cancer Drug Hope
A drug for breast cancer that is more effective than existing medicines may be a step closer thanks to new research.
Untangling Disease-Related Protein Misfolding
Work advances understanding of genetic forms of thrombosis, emphysema, cirrhosis of the liver, neurodegenerative diseases and inflammation, among others.
Early Genetic Changes in Premalignant Colorectal Tissue Identified
Findings point to drivers of early cancer development, targets for cancer prevention therapies.
Harnessing Nature’s Vast Array of Venoms for Drug Discovery
Scripps scientists have developed a method for rapidly identifying venoms.
Nanoparticles Target, Transform Fat Tissue
Nanoparticles designed to target white fat and convert it to calorie-burning brown fat slowed weight gain in obese mice without affecting food intake. This proof-of-concept work could lead to new therapies to treat obesity.
New Cancer Fighters Emerge From Lab
Rice University lab simplifies total synthesis of anti-cancer agent.
Scientists Find Evidence That Cancer Can Arise Changes
Researchers at Rockefeller University have found a mutation that affects the proteins that package DNA without changing the DNA itself can cause a rare form of cancer.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!