Corporate Banner
Satellite Banner
Next Gen Sequencing
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

A Survey of Error-Correction Methods for Next Generation Sequencing

Published: Wednesday, February 20, 2013
Last Updated: Wednesday, February 20, 2013
Bookmark and Share
This article provides a review of error-correction algorithms for NGS data and their comparative evaluation.

Abstract
Error Correction is important for most next-generation sequencing applications because highly accurate sequenced reads will likely lead to higher quality results.Many techniques for error correction of sequencing data fromnext-gen platforms have been developed in the recent years. However, compared with the fast development of sequencing technologies, there is a lack of standardized evaluation procedure for different error-correction methods, making it difficult to assess their relative merits and demerits. In this article, we provide a comprehensive review of many error-correction methods, and establish a common set of benchmark data and evaluation criteria to provide a comparative assessment.We present experimental results on quality, run-time, memory usage and scalability of several error-correction methods. Apart from providing explicit recommendations useful to practitioners, the review serves to identify the current state of the art and promising directions for future research. Availability: All error-correction programs used in this article are downloaded from hosting websites.

This article was puclished online in Briefings in Bioinformatics and is free to access.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,000+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Tool for the Identification of Targeted Sequences from Multidimensional High Throughput Sequencing Data
This article illustrated the use of InsertionMapper which consists of four independently working modules.
Monday, October 07, 2013
In-solution Hybrid Capture of Bisulfite-converted DNA for Targeted Bisulfite Sequencing of 174 ADME Genes
The aim of this study was to develop a method for the analysis of DNA methylation patterns in 174 ADME genes.
Monday, February 11, 2013
Genomic Sequencing in Clinical Trials
In this article, researchers from Northwestern University Feinberg review the current and future directions of clinical research with respect to genomic sequencing.
Wednesday, February 15, 2012
CAPRG: Sequence Assembling Pipeline for Next Generation Sequencing of Non-Model Organisms
In addition to providing evaluation of CAPRG performance, scientists observed that the different assembly (inter-assembly) results could be integrated to enhance the putative gene coverage for any transcriptomics study.
Wednesday, February 15, 2012
Rapid Screening of Complex DNA Samples by Single-Molecule Amplification and Sequencing
Researchers from Karolinska Institutet have developed a simple, rapid and robust method that enables laboratories to perform single-molecule amplicon sequencing from sub-picogram quantities of DNA without the need for special equipment.
Friday, June 03, 2011
Scientific News
How Did The Giraffe Get Its Long Neck?
Clues about the evolution of the giraffe’s long neck have now been revealed by new genome sequencing.
Big Data Can Save Lives
The sharing of genetic information from millions of cancer patients around the world could be key to revolutionising cancer prevention and care, according to a leading cancer expert from Queen's University Belfast.
Making Genetic Data Easier to Search
Scripps team streamlines biomedical research by making genetic data easier to search.
Collaborative Study of WES Offers New Hope
Company has announced that the collaborative study of whole exome sequencing offers new hope for children with white matter disorders.
Using Portable Nanopore DNA Sequencers to Combat Wildlife Crime
University of Leicester researchers aim to develop a test using DNA to identify species at crime scenes in as little as an hour.
TGAC Installs Largest SGI UV 300 Supercomputer for Life Sciences
The Genome Analysis Centre (TGAC) partners with Global HPC hardware giant SGI to address the most complex problems in genomics analysis.
Shining A Light On Bladder Cancer
Researchers scrutinize patterns of mutations in bladder tumor genomes, gleaning insights into the roles of DNA repair and tobacco-related DNA damage.
Monovar Drills Down Into Cancer Genome
Rice, MD Anderson develop program to ID mutations in single cancer cells.
Five New Breast Cancer Genes Found
Discovery of mutations paves the way for personalised treatment of breast cancer.
New Neurodevelopmental Syndrome Identified
Study pinpoints underlying genetic mutations, raising hopes for targeted therapies.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!