Corporate Banner
Satellite Banner
Next Gen Sequencing
Scientific Community
 
Become a Member | Sign in
Home>Resources>White Papers>This White Paper
  White Papers
Scientific News
NASA's DNA Sequencing in Space is a Success
DNA has been sequenced in space for the first time ever for the Biomolecule Sequencer investigation, using the MinION sequencing device.
New Inflammatory Disease Discovered
NIH researchers have discovered a rare and potentially deadly disease - otulipenia - the mostly affects children.
Bringing NGS to the Crime Lab
New technology being validated in BCI lab for use in Ohio missing persons cases.
Expanding Knowledge of Viral Diversity
Environmental datasets help researchers double the number of microbial phyla known to be infected by viruses.
How Cloud Connectivity Can Combat the Reproducibility Crisis
This infographic explains the reproducibility crisis, and how cloud connectivity can help overcome this problem.
The Power of Model Systems
New insights into the influence of host on the gut microbiome are revealed with in situ light sheet fluorescence microscopy and stochastic mathematical modelling.
New Way To Measure Important Chemical Modification On RNA
Technology could advance stem cells’ use in regenerative medicine, UCLA researchers say.
Mapping Antibody Creation in Humans
Researchers have created the first, detailed map of the body's antibody production, which could suggest new treatment options for immune disorders.
Decoding the Genome of the Olive Tree
A team of scientists from three Spanish centers has sequenced, for the first time ever, the complete genome of the olive tree. This work will facilitate genetic improvement for production of olives and olive oil, two key products in the Spanish economy and diet.
Four Newly-Identified Genes Could Improve Rice
A Japanese research team have applied a method used in human genetic analysis to rice and rapidly discovered four new genes that are potentially significant for agriculture. These findings could influence crop breeding and help combat food shortages caused by a growing population.
Scroll Up
Scroll Down

OmicSoft Aligner
Bookmark and Share

OmicSoft Corporation

Whitepaper discussing the technique of aligning next generation sequencing (HTS) data.

OSA is Omicsoft's read aligner designed for high performance alignment of short or long reads to reference libraries (genomes or transcriptomes).

 Key features of OSA:
1. High performance for both single end alignment and paired end alignment. Works on reads with 17-65536 nucleotides.
2. For Illumina reads (17nt or longer), allow any number of mismatches and a single indel in the reads. Can identify and report all available alignments in the genome with specified mismatches/indel.
3. For long reads (e.g. 454 reads or PacificBio reads), allow any number of mismatches and indels in the reads. Use banded Smith-Waterman to find the optimal alignment.
4. Directly align RNA-Seq reads to genome by considering both known and novel exon junctions
5. Directly align fusion reads: reads spliced by two different genes or genomic regions
6. Automatic quality based trimming
7. Automatic adapter trimming
8. Support all common input formats (.fasta; .fastq; .qseq; .sff); directly support .gzip files allowing savings in file space
9. Support multiple threads

Further Information


Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!