Corporate Banner
Satellite Banner
Technology Networks Header
Saturday, August 30, 2014
Technology Networks
 
Register | Sign in
Home Page > Videos > Comprehensive microRNA Expression Profiling in Lineage Specific Human Hematopoiesis
  Videos

Return

Comprehensive microRNA Expression Profiling in Lineage Specific Human Hematopoiesis
NIH

Deep metagenomic sequencing of multiple ruminant guts reveals species-specific microbiomes. Ruminant species such as cattle, sheep, deer, goats and reindeer represent a fascinating opportunity to study gut function and metagenomics. With a solely vegetarian diet, the gut microbiome of ruminants is perfectly adapted to digest and gain energy from plant material. However, different animals have different diets (e.g. grass vs lichen) which require different microbes to digest. We have deep-sequenced the rumen gut microbiome of several ruminant species using the Illumina HiSeq 2000 system, generation several hundred gigabases of sequence data in the process. Here we describe bioinformatic investigations into these data, including assembly into large contigs, prediction and annotation of genes and taxon assignment. We show that the vast majority of sequence data comes from as-yet uncharacterized bacterial species, representing huge potential for discovery of novel enzymes. Finally, we show that ruminants can be clustered together according to their gut microbiome structure and species abundance.

Request more information
Company product page



For access to this article, enter your email address to instantly recieve a Password Reset link.

Please enter your email address below:

Existing users please Sign In here. Don't have an account? Register Here for free access.

Don't have an account? | Register Here

Scientific News
Sequencing Identifies Gene Variant Responsible for Lupus
Research demonstrates it is feasible to identify the individual causes of lupus in patients by using DNA sequencing, allowing doctors to target specific treatments to individual patients.
“Deep sequencing” Picks up Hidden Causes of Brain Disorders
New approach complements whole-genome and whole-exome sequencing.
New Material Could Enhance Fast and Accurate DNA Sequencing
Nanopores in the material MoS2 sequence DNA more accurately, quickly and inexpensively.
ChIP Sequencing Kit for Next Generation Sequencing
The assay kit from Porvair Sciences extends the benefits of their proprietary Chromatrap® solid state ChIP technology.
Illumina's HiSeq X Ten Sequencing Technology for Population Studies
Next-generation sequencing technologies to be implemented at new High-Throughput Genomics Center for the MENA region.
Foodborne Pathogen Detection Speeds Up Dramatically
Next-generation sequencing techniques allow rapidly identification of strains of salmonella, quickening responses to potential outbreaks.
Sequencing Efforts Miss DNA Crucial to Bacteria’s Disease Causing Power
New research suggests that current sequencing protocols overlook crucial bits of information: isolated pieces of DNA floating outside the bacterial chromosome.
Blueprint for the Affordable Genome
Stampede supercomputer powers innovations in DNA sequencing technologies.
Ubiquitous Protein Controls Copying of Resistant DNA
Researchers have demonstrated how the protein could put antibiotic-resistant bugs in handcuffs.
Common Bean Critically Important to the Global Food Supply
The bean genome sequence provides powerful tools to improve critical food crop.
Scroll Up
Scroll Down
Skyscraper Banner
Skyscraper Banner
Follow TechNetcom1 on Twitter
Technology Networks Ltd. on LinkedIn
Go to LabTube.tv