|Microfluidic Sample Extraction Device with an Integrated Pressure Measurement|
J. Varfolomeeva, C. Müller, L. Riegger, H. Reinecke
Bioanalytical applications, like the monitoring of metabolic processes, often require a continuous sample extraction. In this work we describe a microfluidic device which is able to subsequently extract samples in microliter range out of a continuous sample stream and provides an optional integrated channel for the measurement of the fluid pressure.
|Concentration and Mixing Effects on the Production of Amine Hydrochloride Salts in a Confined Impinging Jet Reactor|
Navid F. Ershad, Archie Eaglesham, Don H. Jones and Suzanne M. Kresta
Results show that different AHC salts can be formed under different process conditions.
|Cytosolic Delivery of Anticancer Drug Using Endosomolytic Peptide Bearing Nanoparticles Against Solid Tumor|
Satish Shilpi, Sanjay K. Jain
The objective of the present project is to develop transferrin coupled biodegradable nanoparticles (NPs) with high encapsulation efficiency (Doxorubicin). GALA (Glutamic acid-alanine-leucine alanine) a pH sensitive fusogenic endosomolytic peptide is added to the formulation to enhance the endosomal lysis that will further potentiate the delivery of anticancer drug inside tumor cell as well as prevent loss of drug via endosomes.
|Highly Efficient Activated Carbon From Palm Shell as an Adsorbent of Toxin/Poison|
M.M. Rahman, B. S. Mohsina, K.M. Sharif, B. Y. Kamaruzzaman, M. B. Awang
Highly efficient activated carbon as an adsorbent of toxins has been successfully produced from palm shell through chemical activation process using phosphoric acid as activating agents.
|Oral Health Management of a Patient with 47 XYY Syndrome|
Dr Altaf H Shah, Prof. Amjad H Wyne and Prof. Rita Khounganian
The 47XYY syndrome is an aneuploidy of sex chromosomes, where a human male receives an extra Y-chromosome making a total of 47 instead of the usual 46.
|The Challenges of Relieving Cancer Pain: A Literature Review|
This study aims to explore the discrepancy between the increasing array of treatments for cancer pain, as well as the evidence that it can be managed effectively in the majority of cases, and its persisting prevalence.
|Colony Forming Cell (CFC) Assays Predict for Increased Clinical Neutrophenia with Combination Therapies|
Dos Santos G, Mergaert A and Clarke E.
This study aimed to assess if the CFC assay could also be useful at predicting the increased toxicity of drug combinations relative to the toxicity caused by the relevant single agent.
|Predictive in silico Screening to Determine Vector-Mediated Transport Properties for the Blood-Brain Barrier Choline Transporter|
Sergey Shityakov and Carola Förster
An attempt to analyze vector-mediated transport properties for the blood-brain barrier choline transporter (BBBCHT) was made to assess and improve drug delivery to the central nervous system.
|Comparison of Dissociated Phoria Measuring Methods. Repeatability and Reliability|
Ane Murueta-Goyena Larrañaga
The aim of this study is to determine the reliability and compare reproducibility of different dissociated phoria measure tests.
|Fast Liquid Differential Scanning Calorimetry (FLDSC)|
R. Splinter, A.W. van Herwaarden, A. Pfreundt, W.E. Svendsen, D. Istrate, W. van Eijk
Lysozyme experiments show that protein unfolding can be recorded at scan rates of up to 1000 °C/s, and for lysozyme concentrations of 1 % and probably even down to 0.1%.
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