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Microfluidic Sample Extraction Device with an Integrated Pressure Measurement
J. Varfolomeeva, C. Müller, L. Riegger, H. Reinecke

Bioanalytical applications, like the monitoring of metabolic processes, often require a continuous sample extraction. In this work we describe a microfluidic device which is able to subsequently extract samples in microliter range out of a continuous sample stream and provides an optional integrated channel for the measurement of the fluid pressure.

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Concentration and Mixing Effects on the Production of Amine Hydrochloride Salts in a Confined Impinging Jet Reactor
Navid F. Ershad, Archie Eaglesham, Don H. Jones and Suzanne M. Kresta

Results show that different AHC salts can be formed under different process conditions.

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Cytosolic Delivery of Anticancer Drug Using Endosomolytic Peptide Bearing Nanoparticles Against Solid Tumor
Satish Shilpi, Sanjay K. Jain

The objective of the present project is to develop transferrin coupled biodegradable nanoparticles (NPs) with high encapsulation efficiency (Doxorubicin). GALA (Glutamic acid-alanine-leucine alanine) a pH sensitive fusogenic endosomolytic peptide is added to the formulation to enhance the endosomal lysis that will further potentiate the delivery of anticancer drug inside tumor cell as well as prevent loss of drug via endosomes.

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Highly Efficient Activated Carbon From Palm Shell as an Adsorbent of Toxin/Poison
M.M. Rahman, B. S. Mohsina, K.M. Sharif, B. Y. Kamaruzzaman, M. B. Awang

Highly efficient activated carbon as an adsorbent of toxins has been successfully produced from palm shell through chemical activation process using phosphoric acid as activating agents.

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Oral Health Management of a Patient with 47 XYY Syndrome
Dr Altaf H Shah, Prof. Amjad H Wyne and Prof. Rita Khounganian

The 47XYY syndrome is an aneuploidy of sex chromosomes, where a human male receives an extra Y-chromosome making a total of 47 instead of the usual 46.

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The Challenges of Relieving Cancer Pain: A Literature Review
Rayna Patel

This study aims to explore the discrepancy between the increasing array of treatments for cancer pain, as well as the evidence that it can be managed effectively in the majority of cases, and its persisting prevalence.

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Colony Forming Cell (CFC) Assays Predict for Increased Clinical Neutrophenia with Combination Therapies
Dos Santos G, Mergaert A and Clarke E.

This study aimed to assess if the CFC assay could also be useful at predicting the increased toxicity of drug combinations relative to the toxicity caused by the relevant single agent.

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Predictive in silico Screening to Determine Vector-Mediated Transport Properties for the Blood-Brain Barrier Choline Transporter
Sergey Shityakov and Carola Förster

An attempt to analyze vector-mediated transport properties for the blood-brain barrier choline transporter (BBBCHT) was made to assess and improve drug delivery to the central nervous system.

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Comparison of Dissociated Phoria Measuring Methods. Repeatability and Reliability
Ane Murueta-Goyena Larrañaga

The aim of this study is to determine the reliability and compare reproducibility of different dissociated phoria measure tests.

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Fast Liquid Differential Scanning Calorimetry (FLDSC)
R. Splinter, A.W. van Herwaarden, A. Pfreundt, W.E. Svendsen, D. Istrate, W. van Eijk

Lysozyme experiments show that protein unfolding can be recorded at scan rates of up to 1000 °C/s, and for lysozyme concentrations of 1 % and probably even down to 0.1%.

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Showing Results 1 - 10 of 889
Scientific News
Clues to Congenital Heart Disease
Non-inherited mutations in hundreds of genes together account for about 1 in 10 cases of severe congenital heart defects.
New DNA Cattle Test Beefs up Dairy and Meat Quality
A genomics technique developed at Cornell to improve corn can now be used to improve the quality of milk and meat.
New Software Spots, Isolates Cyber-attacks to Protect Networked Control Systems
Software algorithm detects and isolates cyber-attacks on networked control systems that are becoming increasingly important to national infrastructure
Computational Tool Translates Complex Data into 2-Dimensional Images
May allow doctors to track progression of cancer, response to treatment, and risk of relapse.
Program for Breakthrough Biomedical Research to Celebrate 15 Years
A program that fosters basic science projects of potentially high impact is celebrating 15 years of discovery at UC San Francisco.
Environmental Law Institute Recognizes Penn State Wetlands Scientist
Robert P. Brooks, a wetlands scientist at Penn State, has received the 2013 National Wetlands Award for Science Research.
Scientists Identify Molecular Trigger for Alzheimer’s Disease
New research establishes nature of malfunction in protein molecules that can lead to onset of dementia.
TATAA Strengthens Quality Assurance Program
TATAA Biocenter expands offerings using AATI’s Fragment Analyzer™ to assess RNA quality in gene expression analysis.
Non-Wetting Fabric Drains Sweat
Waterproof fabrics that whisk away sweat could be the latest application of microfluidic technology developed by bioengineers.
miRNA Regulated Networks Identified in Cystic Fibrosis
The IDT newsletter DECODED features the latest research to rescue the CFTR functionality.
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