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Forced Degradation Study of Expired and Marketed Tablets of Amlodipine by RP-HPLC
Manisha Puranik*, Monilisha Varma

The objective of the current study was to develop simple, accurate, sensitive and stability indicating RP-HPLC method for the determination of per cent drug remained of Amlodipine besylate in the presence of its degradation products in bulk drug, expired tablets and tablets whose expiry date has not been exceeded.

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LC-MS/MS METHOD FOR THE QUANTIFICATION OF PITOFENONE IN HUMAN PLASMA
B.M. Gurupadayya, S. Sharfuddin and R.S. Chandan

We developed LCMS/MS bioanalytical method for quantitative estimation of Pitofenone HCl in plasma is simple, sensitive, accurate, precise, and selective. Percentage recovery shows that the method is free from interference of matrix. The analytical method presented here has proved to be useful for investigation of the characteristics of Pitofenone in human plasma in pharmacokinetic and pharmacogenetic studies.

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Using An in‐vitro Human Airways Model to Study the Effects of e‐cigarettes on Bronchial Epithelial Cells
Vasanthi Bathrinarayanan, P.1 Marshall, L.J.2 Leslie, L.J.1

The prime aim of our study is to use in-vitro human airway models as an effective alternative to replace animals in traditional/E-cigarette research.

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Experimental Evolution in Diatoms - Thermal longterm acclimation in two model diatom species
Katrin Schmidt1, Sinéad Collins2, Thomas Mock1

Experimental Evolution in two model Diatoms

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Microelectrodes for Microdroplet Motion Based On Electrowetting: A Review on Design
Nurul Amziah Md Yunus, Noor Faezah Ismail, Seyed Amin Firouzeh, Zurina Zainal Abidin, Nasri Sulaiman and Izhal Abdul Halin.

The technology is growing rapidly whereby the researchers all over the world have discovered the smaller scale of technology. In micro-nanotechnology, the microfluidic manipulation become useful in many field of applications and one of the most advanced method is electrowetting. The observation and review on the design of microelectrode for droplet motion based on electrowetting with different shapes, sizes and fabrication regarding on the different application are hereby reported.

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Real Time Dual-Channel Multiplex SERS Ultradetection
Sara Abalde-Cela,†,‡ Chris Abell,† Ramón A. Álvarez-Puebla, ?,§ and Luis M. Liz-Marzán‡,?,#

Real time On-line multiplex SERS detection in a microfluidic device.

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Antioxidant and Free Radicals Scavenging Activity of Biomolecules: Hydroxamic Acids
Bharati Verma and Rama Pande

In the present poster attention is focused towards the investigation of antioxidant and free radicals scavenging activity of N-aryl substituted hydroxamic acids by DPPH method which is based on the reduction of alcoholic DPPH solutions in presence of a hydrogen donating antioxidant, hydroxamic acids.

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"In-vitro studies on hydroxamic acid- CT DNA binding"
Rubi Khilari

In vitro studies of five the interaction between five different derivatives of hydroxamic acids, N-phenyl 2,4dichloro phenoxybutyro, N-m-tolyl 2,4 dichlorophenoxyglutero, N-m-tolyl-4-chlorophenoxyaceto, N-m-chloro-phenyl-tertiarybutylbenzo and N-p-tolyl-iso-valero hydroxamic acids and calf thymus DNA was investigated under simulated physiological condition.

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Efficacy of Gene Therapy in Restoring Vision in Leber's Congenital Amaurosis
Elizabeth O'Donnell

The research reviews current knowledge of the genetic causes of Leber's congenital amaurosis (LCA) and the development of a gene therapy intervention for LCA. The efficacy as well as the limitations of this form of treatment are evaluated in detail and recommendations are made for the future directions of gene therapy for Leber's congenital amaurosis.

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Validation of HPLC analytical method for determination of biogenic amines in agricultural products
Hyeock Yoon, Jae-Hyung Mah

An analytical method was validated for the quantitative determination of biogenic amines (BA) in agricultural products. The validation results fulfill AOAC criteria and recommendations. This method has been applying to analyze BA in agricultural products for a total dietary survey in Korea.

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Showing Results 1 - 10 of 1083
Scientific News
Gene Therapy Provides Safe, Long-Term Relief for Patients with Severe Hemophilia B
Gene therapy pioneered by St. Jude Children’s Research Hospital, University College London and the Royal Free Hospital provides men with hemophilia B reliable relief from the bleeding disorder.
Protein Predicts Response To New Immunotherapy Drug
Trial shows that response to treatment may be predicted by the presence of an immune-suppressing protein in non-cancerous immune cells.
NIAID/GSK Experimental Ebola Vaccine Appears Safe, Prompts Immune Response
Results from NIH Phase 1 clinical trial support accelerated development of candidate vaccine.
Researchers Develop Efficient Method to Produce Nanoporous Metals
New technique to manufacture nanoporous metals is cheap and can be done over many scales.
Turkeys may be Lifesavers
Antibiotic to target staph infections, strep, comes from good bacteria in turkeys.
A Hybrid Vehicle That Delivers DNA
University at Buffalo researchers are developing new technology to improve DNA vaccines. The new transport system for DNA vaccines could help treat HIV, malaria, HPV and other major illnesses.
Big Data Set To Make A Big Difference In Childhood Cancer Treatment
UTS researchers are working with the Kids Research Institute to visualise large quantities of patient data to better diagnose and treat childhood cancer patients.
Two Studies Identify A Detectable, Pre-Cancerous State In The Blood
Findings pave way for new lines of cancer research focused on detection and prevention.
A Link between DNA Transcription and Disease-Causing Expansions Which Lead to Hereditary Disorders
A Tufts University study explores the relationship between transcription and the expansions of DNA repeats.
Did You Hear The One About The Two Businessmen On A Plane?
EquipNet’s vision ‘to revolutionize the way companies manage their surplus assets’ was first conceived at 30,000 feet somewhere between Chicago and Boston in 1999. Here we learn more about the company's first 15 years.
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