|Inverted Y Approach to Lumbosacral region - Analysis of 525 cases over 10 years|
Dr Krishna Kumar and Dr Renjith Kumar
Traditional approach to lumosacral region utilizes midline incision, which often requires long incision to get sufficient exposure. We describe our experience with inverted Y approach to lumbosacral junction.
|Alternative Cellular Energy Based Therapy of Childhood Diarrhea|
Rafael R. Izaguirre, Miguel R. Guzman, Rafael C. Fuentes, Carlos E. Mena, Emillio Penate, W John Martin
Acute infectious diarrhea is a major cause of morbidity and mortality in the developing world; especially among children less than 5 years of age. As restoring normal cellular function is an energy-requiring process, patients with diarrhea could potentially benefit from receiving an alternative (non-mitochondria) source of cellular energy.
|Effect of cinnamomum tamala leaves extracts on collagen cross-linking and tensile strength in wound healing in diabetic rats|
Rupesh Soni, Amit Vairagi and D. N. Srivastava
Diabetes can result in development of several complications, including delayed wound healing. Diabetic wounds are slow, non-healing wounds that can persist for weeks despite adequate and appropriate care.
|Does the increase of exosomal microRNAs reflect an activated immune system in melanoma?|
Nina Koliha, Florian S. Dreyer , Jochen Dindorf , Andreas Bosio, Andreas S. Baur , and Stefan Wild
Cutaneous malignant melanoma is a form of skin cancer that accounts for 65% of skin cancer-related deaths. The incidence increases continuously, and while early detection leads to nearly 100% survival rates, the mortality raises to greater than 80% for patients with advanced disease.
|A Distinctive Analysis of Fluid Flow Behaviour in an AC Electroosmotic Micropump|
Nurul Amziah Md Yunus, Farideh Abhari, Mohd Nizar Hamidon, Zurina Zainal Abidin, Izhal Abdul Halin, Gerard H. Markx and Nicolas G. Green
Microfluidic systems are used for chemical and biological analyses, sensing, drug delivery and molecular separation.
|Stealth-Adapted Viruses and Viteria: Insights into Virus Construction, Replication and Potential Therapies|
W. John Martin
There is an increasing incidence of diseases with accompanying signs and symptoms of brain damage. These include neurological and psychiatric illnesses, childhood behavioral disorders, and such common conditions as chronic fatigue, Gulf War Syndrome, so-called “chronic Lyme disease”, and many cancers. Altogether, these diseases have an enormous social impact.
|A New Approach to Increase Yields and Improve Functionality of Recombinant Proteins|
Antti Vasala, BioSilta Oy, Oulu, Finland
The ability to express and extract fully functional proteins in sufficient quantities from bacterial cultures is a prerequisite for many projects in which recombinant proteins are required for structural studies, functional characterization, as assay components or for other applications. However, low yield, poor solubility and lack of functionality are often associated with, what should be, a routine procedure.
|Functional Monoliths for Flow Processes by RAFT Polymerisation|
Kristine J. Barlow, Victor Bernabeu, Xiaojuan Hao, Timothy C. Hughes, Oliver E. Hutt, Anastasios Polyzos, Kathleen A. Turner, Graeme Moad
Polymeric monoliths have recently emerged as a new class of solid supports for stoichiometric and catalytic reactions in continuous flow synthesis.
|Low-cost “Plug & Play” On-Chip Valve and Pump for Thermoplastic Microfluidics|
Mousavi Shaegh Seyed Ali, Wang Zhenfeng, Toh Guek Geok, Soh Yong Chear
Scientists have developed a novel on-chip valving solution for thermoplastic microfluidic devices, which is reliable, easy to implement, and has low-cost fabrication.
|Novel Nucleosomics Serum Biomarkers for the Detection of Colorectal Cancer|
S Holdenrieder, Y Dharuman, J Standop, M Herzog, N Trimpop, K Hettwer, K Simon, Steffen Uhlig and Jake Micallef
As colorectal cancers are often detected at late tumor stages when prognosis of the patients is poor, powerful blood-based biomarkers are needed for earlier detection. In recent years it has become clear that epigenetic changes to chromatin and its constituent nucleosomes are associated with carcinogenesis and elevated levels of nucleosomes are present in the blood of cancer patients.
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