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Molecular Dynamics Simulation Study of Pulmonary Surfactant Interacting With Nanoparticles

MD simulation studies using NAMD of lipid bilayers supported on alpha-quartz (nanoparticles) and kaolinite with explicit water molecules will be presented to understand the physiochemical effects of nanoparticles on pulmonary surfactant.

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Pharmacokinetic Delivery and Metabolizing Rate of Nicardipine Incorporated in Hydrophilic and Hydrophobic Cyclodextrins using Two-Compartment Model

The dispersion routes of cyclodextrin complexes with nicardipine (NC), such as hydrophilic hydroxypropyl-ß-cyclodextrin (NC/HPßCD) and hydrophobic triacetyl-ß-cyclodextrin (NC/TAßCD), through the body for controlled drug delivery and sustained release have been examined.

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Cloning And Purification of a Putative Repressor Protein from Arthrobacter nicotinovorans Pao1

The soil bacterium Arthrobacter nicotinovorans carries the pAO1 catabolic megaplasmid which enables it to grow on nicotine (Igloi and Brandsch, 2003).

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Recycled Gas Flow Control to Optimize Reaction Conversion and the Accomplishment of Heat Integration in Benzene Production through Hydrodealkylation of Toluene

In this work, a benzene production plant through hydrodealkylation process was investigated through a simulation by Aspen Plus V7.2® and run based on the real data obtained from a benzene production plant operating in the United States.

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Rapid Concentration of Particles in Microfluidics using AC Electrothermal Effect with Laser Illumination

In this study, the formation of a toroidal microvortex by AC electrothermal (ACET) effect was numerically visualized using COMSOL v4.2a multiphysics software. AC voltage was applied to the two parallel electrodes in a microchannel to generate temperature gradient in the fluids.

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A Novel Synthetic Peptide as a Tool for Microvesicles / Exosomes isolation ©

We have engineered and validated a synthetic peptide (Vn96*) with specific affinity for canonical heat shock proteins (HSPs) as a tool for rapid isolation of Exosomes or extracellular microvesicles (together referred to as eMVs here) from cell culture media, human and animal body-fluids.

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Determination of Metabolically Unstable Drugs in Blood by Heat-Stabilized DBS and LC-MS/MS

The aims of this work were to investigate drug stability prior to, during and after blood spot sampling, using procaine, prulofloxacine, esmolol, and acetylsalisylic acid as examples of drug compounds with limited stability and to compare conventional DBS sampling procedure with DBS sampling including heat stabilization.

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Hypothesis of an Existence of a Reverse Pathway (Rp) which Passes Genetic Information from Polypeptide Antigens to Ig Genes in B-Lymphocytes
Victor J. Alexander

Results of this research will bring new more effective treatment methods of many immune related diseases, including cancer.

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Microfluidic analysis of amino acids using aminoacyl-tRNA synthetase coupled with spectrophotometric detection

Analyses of free amino acids in biological fluids?—?such as urine and plasma?—?can be useful in determining disease status in clinical diagnoses [1]. In the food industry, unique changes in amino acid concentrations are useful markers of freshness, nutrition, and taste.

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Showing Results 91 - 100 of 1004
Scientific News
Understanding and Improving the Body's Fight Against Pathogens
A*STAR scientists find new targets for modulating antibody response.
New Advances in the Pre-clinical Evaluation of Hepatitis B Therapies
Imperial College London to present first public HBV Data from CN Bio in vitro liver model.
Single Animal to Human Transmission Event Responsible for 2014 Ebola Outbreak
NIH-funded scientist uses latest genomic technology to make discovery.
Watching Molecules ‘Dance’ in Real Time
Trapping light at the nanoscale enables real-time monitoring of individual molecules bending and flexing may aid in our understanding of how changes within a cell can lead to diseases such as cancer.
Repressing the Repressors May Drive Tissue-Specific Cancers
Stowers scientists establish Drosophila and mammalian models to study mutations found in pediatric brain tumors.
Genetic Basis for Rabbit Domestication Revealed
Research presents key findings in the DNA make-up of the common mammal’s brain and nervous system, which determines how wild rabbits were genetically transformed to domestic rabbits.
Fighting Prostate Cancer with a Tomato-Rich Diet
New research suggests that men who eat over 10 portions of tomatoes a week have an 18% lower risk of developing prostate cancer.
Scientists Looking Across Human, Fly and Worm Genomes Find Shared Biology
Studies reveal powerful commonalities in biological activity and regulation among species.
Genetics Used to Improve Plants for Bioenergy
An upcoming genetics investigation into the symbiotic association between soil fungi and feedstock plants for bioenergy production could lead to more efficient uptake of nutrients, which would help limit the need for expensive and polluting fertilizers.
NIH to Launch Human Safety Study of Ebola Vaccine Candidate
Trial is First in Series of Accelerated Safety Studies of Ebola Vaccines.
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