|Progressing 3D Spheroid Analysis into a HTS Drug Discovery Method|
Sarah Kessel, Eric Sincoff, Olivier Dery
This study demonstrates that the cell culture assay for tumorsphere size was successfully adapted to 384-well plate for a 3D spheroid assay using U-bottom low attachment 384-well and the Celigo Automated Imager for image acquisition and analysis. Moreover, the utilization of an imager provided insight on sphere and cell fate after long term drug treatment.
|Expression Profiling of Circulating Tumor Cells: a Prognostic and Predictive Biomarker in Cancer.|
Mikael Kubista, Robert Sjöback,Marie Jindrichova, Eva Rohlova, Vendula Novosadová, Siegfrid Hauch, Bahriye Aktas, Mitra Tewes,Maren Bredemeier, and SabineKasimir-Bauer
We show non-responders to treatment among breast cancer patients can be identified by expression profiling of circulating tumor cells
|Forced Degradation Study of Expired and Marketed Tablets of Amlodipine by RP-HPLC|
Manisha Puranik*, Monilisha Varma
The objective of the current study was to develop simple, accurate, sensitive and stability indicating RP-HPLC method for the determination of per cent drug remained of Amlodipine besylate in the presence of its degradation products in bulk drug, expired tablets and tablets whose expiry date has not been exceeded.
|LC-MS/MS METHOD FOR THE QUANTIFICATION OF PITOFENONE IN HUMAN PLASMA|
B.M. Gurupadayya, S. Sharfuddin and R.S. Chandan
We developed LCMS/MS bioanalytical method for quantitative estimation of Pitofenone HCl in plasma is simple, sensitive, accurate, precise, and selective. Percentage recovery shows that the method is free from interference of matrix. The analytical method presented here has proved to be useful for investigation of the characteristics of Pitofenone in human plasma in pharmacokinetic and pharmacogenetic studies.
|Using An in‐vitro Human Airways Model to Study the Effects of e‐cigarettes on Bronchial Epithelial Cells|
Vasanthi Bathrinarayanan, P.1 Marshall, L.J.2 Leslie, L.J.1
The prime aim of our study is to use in-vitro human airway models as an effective alternative to replace animals in traditional/E-cigarette research.
|Experimental Evolution in Diatoms - Thermal longterm acclimation in two model diatom species|
Katrin Schmidt1, Sinéad Collins2, Thomas Mock1
Experimental Evolution in two model Diatoms
|Microelectrodes for Microdroplet Motion Based On Electrowetting: A Review on Design|
Nurul Amziah Md Yunus, Noor Faezah Ismail, Seyed Amin Firouzeh, Zurina Zainal Abidin, Nasri Sulaiman and Izhal Abdul Halin.
The technology is growing rapidly whereby the researchers all over the world have discovered the smaller scale of technology. In micro-nanotechnology, the microfluidic manipulation become useful in many field of applications and one of the most advanced method is electrowetting. The observation and review on the design of microelectrode for droplet motion based on electrowetting with different shapes, sizes and fabrication regarding on the different application are hereby reported.
|Real Time Dual-Channel Multiplex SERS Ultradetection|
Sara Abalde-Cela,†,‡ Chris Abell,† Ramón A. Álvarez-Puebla, ?,§ and Luis M. Liz-Marzán‡,?,#
Real time On-line multiplex SERS detection in a microfluidic device.
|Antioxidant and Free Radicals Scavenging Activity of Biomolecules: Hydroxamic Acids|
Bharati Verma and Rama Pande
In the present poster attention is focused towards the investigation of antioxidant and free radicals scavenging activity of N-aryl substituted hydroxamic acids by DPPH method which is based on the reduction of alcoholic DPPH solutions in presence of a hydrogen donating antioxidant, hydroxamic acids.