Human iPSC-derived hepatocytes and cardiomyocytes for drug toxicity testing AnnandRR; Vardaro R; Hamilton B; Akakira R; Tamura K; Yoshida S; Lin YC; Toyoda D; Kogami H; Okuda Y; Watanabe T; Inamura M
Human iPS-derived hepatocytes (ReproHepato™) and cardiomyocytes (ReproCardio 2™) are useful for in vitro toxicity assays.
Applications of scCO2 as a “Green” Solvent in the Textile Industry A. Lutz, A. Kaziunas, R. Schlake, M. Anand, and J.P. Hobbs
Using Supercritical CO2 to dye textiles.
Alterations in serum thrombotic biomarker in patients with acute myocardial infarction Abdullah S. Alhomida
A combination of these biomarkers could serve as a useful biomarker tool to assess the prognosis of AMI. (This study was supported by National Plan for Science and Technology Program by King Saud University Project Number 08-BIO571-02).
Using Cresset to grow and link distant fragment hits with sensible chemistry M J Slater; T Cheeseright
We describe a further extension to our fragment growing methodology to aid fragment optimisation through linking fragments that have been shown to bind to distinct (distant or adjacent) pockets.
Improved Small RNA Library Preparation Workflow for Next-Generation Sequencing Sabrina Shore, Jordana Henderson, Anton McCaffrey, Gerald Zon, Richard Hogrefe
We describe an optimized small RNA NGS library prep workflow using chemically modified adapters which suppresses adapter dimers, allows for RNA inputs down to 1 ng and eliminates the need for a gel purification step, thus allowing full automation not previously possible.
Non-invasive Liquid Biopsy Frauke Henjes1, Lise Aagaard1, Darren Ellis1, Hannah Lindstroem1, Morten Oksvold2,3, Axl Neurauter1, Ketil W. Pedersen1.
Paramagnetic Dynabeads® magnetic beads provide a versatile, automation friendly tool for fast sensitive and high throughput isolation that can be tailored to isolate specific circulating biomarkers such as cells, exosomes and nucleic acids.
Development of a novel xeno-free medium for feeder-free culture of human stem cells Annand R; Okuda Y; Inamura M
A new xeno-free medium (ReproXFTM) has been developed for feeder-free culture of stem cells.
Novel culture medium using a small-molecule agonist of thrombopoetin receptor Hondo M1; Nishino T2; Inamura M1
ReproHSC medium for the culture of hematopoietic stem cells. facilitates the culture and expansion of CD34+/CD38- cells that retain their HSC properties
Human iPSC-derived hepatocytes ReproHepateTM for CYP assay and drug toxicity testing Annand R; Akahira R; Tamura K; Inamura M
We developed iPSC-derived hepatocytes and used them for CYP induction and cytotoxicity assays.