|Improved Small RNA Library Preparation Workflow for Next-Generation Sequencing|
Sabrina Shore, Jordana Henderson, Anton McCaffrey, Gerald Zon, Richard Hogrefe
We describe an optimized small RNA NGS library prep workflow using chemically modified adapters which suppresses adapter dimers, allows for RNA inputs down to 1 ng and eliminates the need for a gel purification step, thus allowing full automation not previously possible.
|Non-invasive Liquid Biopsy|
Frauke Henjes1, Lise Aagaard1, Darren Ellis1, Hannah Lindstroem1, Morten Oksvold2,3, Axl Neurauter1, Ketil W. Pedersen1.
Paramagnetic Dynabeads® magnetic beads provide a versatile, automation friendly tool for fast sensitive and high throughput isolation that can be tailored to isolate specific circulating biomarkers such as cells, exosomes and nucleic acids.
|Development of a novel xeno-free medium for feeder-free culture of human stem cells|
Annand R; Okuda Y; Inamura M
A new xeno-free medium (ReproXFTM) has been developed for feeder-free culture of stem cells.
|Novel culture medium using a small-molecule agonist of thrombopoetin receptor|
Hondo M1; Nishino T2; Inamura M1
ReproHSC medium for the culture of hematopoietic stem cells. facilitates the culture and expansion of CD34+/CD38- cells that retain their HSC properties
|Human iPSC-derived hepatocytes ReproHepateTM for CYP assay and drug toxicity testing |
Annand R; Akahira R; Tamura K; Inamura M
We developed iPSC-derived hepatocytes and used them for CYP induction and cytotoxicity assays.
|Alzheimer's disease model cells derived from human iPS cells|
Honda M; Kitogo T; Kogami H; Inamura M
Alzheimer's disease model neurons were created from iPS cells to enable functional, cell-based assays for AD.
|Flexible automated platform for blood group genotyping on DNA microarrays|
S. Paris1, D. Rigal1, V. Barlet1, M. Verdier1, N. Coudurier2, P. Bailly3, J.-C. Brès1,4
The purpose of this project was to set up and validate a flexible robotic platform using 96-well DNA microarray for multiplex blood group genotyping.
|Combined Use of Rheometry and GPC/SEC for Characterising Ionic Polysaccharides|
John Duffy, Bernd Schaefer, Bert Postma
This poster shows how Rheometry and GPC can be complementary tools for characterising the behaviour of polysaccharides in solution
|A novel multi-organ microfluidic chip: on the way to the complexity of a living organism|
Timur R Samatov, Svetlana A Tonevitskaya, Natalya Pulkova, Evgeny A Tonevitsky
A novel physiologically relevant multi-organ chip is developed capable of culturing up to six different organotypic models integrated into a single microfluidic circuit.