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Automated protein digestion workflows for MS-based proteomics applications
Gunnar Dittmar1, Oliver Popp1, Guenter Boehm2, Andreas Bruchmann3

The PAL RTC provides an affordable and reliable platform optimised for medium-throughput peptide preparation for shotgun-proteomics based mass spectrometry.
Reduce hands-on time on repetitive work!
Increase consistency!
Increase reproducibility

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Deciphering Regulatory Mechanisms in M. xanthus Using Isotopic Ratio Outlier Analysis (IROA) for Metabolome-wide Quantitation
Daniel Krug 1,2, Carsten Volz 1, Aiko Barsch 3, Chris Beecher 4, Felice de Jong 4, Rolf Müller 1,2

Comprehensive study of regulation in myxobacteria with an untargeted metabolomics setup using Isotopic Ratio Outlier Analysis (IROA) and UHR-Q-TOF

Reliable relative quantitation of known and unknown metabolites from a myxobacterial mutant strain in response to induction of the transcriptional antirepressor taA

Compound identification facilitated by the use of ultra-high resolution MS and the knowledge of the number of carbons in each molecule due to IROA

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Analysis of Imported Children's Toys for Heavy Metals
Patricia Atkins, Huifang Lang, William Driscoll

Children’s consumer products have been an active focus for study and regulation due to their ability to expose infants and children to potentially damaging and dangerous chemicals.

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Intact Protein LC-MS: How to Overcome the Challenges?
Robert van Ling, Evert-Jan Sneekes, Sebastiaan Dolman, Laurent Rieux, Mauro DePra, Christian Ravnsborg, Dafydd Milton, Remco Swart

Purpose: Facilitate intact protein LC-MS without compromising performance.
Methods: Construct prototypes of integrated column and sprayer dedicated for intact protein separations and compare performance.
Results: Three prototypes have been directly compared and all showed good protein separations, each with their unique area of strength.

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Instant Connect Gas Sampling Valve Module Introducing a New Flexibility in Gas Sampling for GC and GCMS
Stefano Pelagatti, Paolo Magni, Fausto Pigozzo

Purpose: We present a newly developed gas sampling valve module for the Thermo Scientific™ TRACE™ 1300 Series Gas Chromatograph (GC).

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GC-MS/MS ANALYSIS OF BENZODIAZEPINES USING ANALYTE PROTECTANTS
Jeremy Matthews, Alex Chen, Flavio Bedini

Purpose: Assess the feasibility of using analyte protectants to improve the analysis of benzodiazepines.

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GC-MS/MS Analysis of Pesticide Residues in Green Tea Extracted by QuEChERS with Acetonitrile as Final Solvent
Cojocariu C., Morgan P., Silcock P., Pelagatti S., Magni P. and Pigozzo F.

This poster describes the analysis of several challenging pesticides from green tea samples using GC-MS/MS and acetonitrile as final extraction solvent. The compounds analysed are representatives of various classes of pesticides, such as carboxamids, OC, OP, pyrethriods, aromatic, phenylamides.

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Exploring The Benefits Of Automated Unattended Sample Derivatization Prior To Gas Chromatography Analysis
A. Caruso, M. Santoro, P. Magni, S. Pelagatti, R. Facchetti

Purpose: Exploring the possibility to perform the sample preparation steps necessary for the derivatization of analytes in a fully automated and reliable way by means of the same robotic sampler used for sample injection into the gas chromatograph.
Methods: As an example of application we screened dairy products for melamine and its derivates presence via GC-MS/MS.
Results: The outcome are good and precise results that show how it is possible to reliably automate sample preparation opera

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Determination of Veterinary Drug Residues in Milk by GC/MS and GC/ECD
Yu Chongtian, Lv Jianxia

Purpose: Develop a rapid, sensitive method for determining amitraz and its metabolites in milk.
Methods: Samples were hydrolyzed in acidic condition and extracted with hexane. After derivativation, the samples were analyzed by GC-ECD or directly by GC-MS.
Results: The results show that GC-MS determination of amitraz and its metabolites is rapid and sensitive.

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Showing Results 121 - 130 of 1110
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New Blood Test For Aggressive Bone Cancer
Researchers at the University of East Anglia are developing a simple blood test to diagnose bone cancer thanks to funding from the Big C.
UBC Engineers Develop Biochem Point-of-Care Lab for Smartphones
UBC Okanagan takes lab on a chip technology to a new inexpensive level.
New Cancer-Fighting Strategy Would Harden Cells to Prevent Metastasis
Potential drug for pancreatic cancer now being tested in animals.
NIH Researchers Tackle Thorny Side of Gene Therapy
Pre-clinical studies in mice reveal ways to reduce cancer risk with modified treatment.
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