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Accurate Determination of Moisture Content of Soft Contact Lenses by Near-Infrared (NIR) Spectroscopy
Dr. Hari Narayanan, Dr. Keith Freel

NIR spectroscopy was used to determine moisture content in soft contact lenses to and accuracy of 1%. Various sample presentation methods were used and the results were compared.

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Employing Design of Experiments (DoE) to Evaluate the Robustness of an Automated Content Uniformity Method for the Triple Fixed Dose Combination Tablets
Irena Maksimovic, Dongsheng Bu, David Lloyd

The Design of Experiments study was employed to optimize the operating ranges of the critical sample extraction parameters for the content uniformity determination of three actives in Triple Fixed Dose Combination tablets using Tablet Processing Workstation bench-top robotic system.

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Employing Design of Experiments (DoE) to Evaluate the Robustness of an Automated Content Uniformity Method for the Triple Fixed Dose Combination Tablets
Irena Maksimovic, Dongsheng Bu, David Lloyd

The Design of Experiments study was employed to optimize the operating ranges of the critical sample extraction parameters for the content uniformity determination of three actives in Triple Fixed Dose Combination tablets using Tablet Processing Workstation bench-top robotic system.

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A Mass Spectrometer for Elemental Analysis based on Fieldable Technologies
Hilary Brown, Jennifer Speer, John Gerling, and Kenyon Evans-Nguyen

Laser ablation and a Microwave Plasma Torch (MPT) were coupled in order to obtain elemental information from solid samples. The MPT was incorporated as a less costly and more portable alternative to the ICP. MPT was also added to help improve the signal from just the laser ablation alone.

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Accurate Determination of Moisture Content of Soft Contact Lenses by Near-Infrared (NIR) Spectroscopy
Dr. Hari Narayanan, Dr. Keith Freel

NIR spectroscopy was used to determine moisture content in soft contact lenses to and accuracy of 1%. Various sample presentation methods were used and the results were compared.

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Investigation of Chemical Contaminants in Soils Following Superstorm Sandy
Amy C Mandigo*, Dana J DiScenza*, Alison R Keimowitz†, and Neil Fitzgerald*

Investigation of Chemical Contaminants in Soils Following Superstorm Sandy

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Rapid Identification of Microorganisms by Touch Spray and Paper Spray Ambient Ionization
Ahmed M. Hamid, Alan K. Jarmusch, Valentina Pirro and R. Graham Cooks

The rapid and accurate identification of microorganisms is necessary in order to improve public health. Molecular-based identification allows for rapid patient treatment and provides more accurate diagnoses, two crucial aspects for successful treatment, yet a great challenge. In this work PS-MS, an existing ambient method, and TS-MS, a newly developed technique, are being utilized in the rapid discrimination of microorganisms (<2 min).

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Rapid analysis of 3D tumour spheroids in soft agar and on ultra-low attachment plates using a laser scanning imaging system
Anne F Hammerstein, Diana Caracino, and Paul Wylie

The requirement for better in-vitro models that are compatible with high-throughput screening campaigns has led to the development of 3D cell cultures models, especially muliticellular spheroids, which retain many of the morphological and genetic traits of tumours.
Here we describe the formation of such spheroids by two methods: on ultra-low attachment plates and in semi-solid agarose. Both methods are compatible with 96- and 384-well microplate formats.

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Combining low and high volume liquid handling capabilities for ADME screening
Joby Jenkins, Kevin Moore, Stephen Fowler, Pascal Schenk

In this study we demonstrate the integration of two liquid handlers to extend the volume dispensing range creating low-volume assay-ready plates with high accuracy and precision. This was then successfully applied to a CYP inhibition assay.

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Showing Results 131 - 140 of 1068
Scientific News
Researchers Develop Efficient Method to Produce Nanoporous Metals
New technique to manufacture nanoporous metals is cheap and can be done over many scales.
Turkeys may be Lifesavers
Antibiotic to target staph infections, strep, comes from good bacteria in turkeys.
A Hybrid Vehicle That Delivers DNA
University at Buffalo researchers are developing new technology to improve DNA vaccines. The new transport system for DNA vaccines could help treat HIV, malaria, HPV and other major illnesses.
Big Data Set To Make A Big Difference In Childhood Cancer Treatment
UTS researchers are working with the Kids Research Institute to visualise large quantities of patient data to better diagnose and treat childhood cancer patients.
Two Studies Identify A Detectable, Pre-Cancerous State In The Blood
Findings pave way for new lines of cancer research focused on detection and prevention.
New Advance in Cryopreservation Could Change Management of World Blood Supplies
Engineers have identified a method to rapidly prepare frozen red blood cells for transfusions.
New Study Reveals Why Some People May be Immune to HIV-1
Natural genetic variation in a protective antiviral enzyme holds promise for new therapies.
Protein Key To The Development Of Blood Stem Cells Identified
Understanding the self-replication mechanisms is critical for improving stem cell therapies for blood-related diseases and cancers.
Fast, Low-cost DNA Sequencing Technology One Step Closer To Reality
ASU Regents' Professor Stuart Lindsay led a team of scientists from Arizona State University's Biodesign Institute and IBM's T.J. Watson Research Center in the development of a prototype DNA reader that could make whole genome profiling an everyday practice in medicine.
Amazing Feet Of Science: Researchers Sequence The Centipede Genome
What it lacks in genes, it certainly makes up for in legs: the genome of the humble centipede has been found to have around 15,000 genes – around 7,000 fewer than a human.
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