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A multi-resonances valveless micropump with high fluid transportation efficiency
Ming-Che Hsieh, Min-Fan Huang, and An-Bang Wang

A multi-resonances valveless micropump equipping with inlet/outlet elastic chambers of intendedly-designed stiffness was successfully realized to solve the low efficiency problem. Besides, a theoretical model based on Hydraulic-electrical-Analogy was also proposed to precisely predict its characteristics of dynamic behavior.

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A novel multi-organ microfluidic chip: on the way to the complexity of a living organism
Timur R Samatov, Svetlana A Tonevitskaya, Natalya Pulkova, Evgeny A Tonevitsky

A novel physiologically relevant multi-organ chip is developed capable of culturing up to six different organotypic models integrated into a single microfluidic circuit.

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ENZYME COATED MAGNETIC NANOPARTICLES FOR USE IN CONTINUOUS FLOW MICROFLUIDIC DEVICES
Ferenc Ender, Diana Weiser, Andras Vitez, Laszlo Poppe

A novel Lab-on-a-Chip platform is presented incorporates micro-sized magnetic reaction cells capable of anchoring protein-coated MNPs addressable and selectively. Such platform allows the design of highly flexible and "programmable" execution of multienzyme processes for biocatalytic or diagnostic purposes.

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Continuous Collection of Stem Cells from a Human Placenta Perfusion Co-Culture
John J.S. Cadwell & James C. Hardy

The potential for human placenta-derived cells to produce stem cells in a hollow fiber bioreactor co-culture system was investigated.

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Electric Field-Induced Release and Measurement (EFIRM) can detect EGFR mutations directly from body fluids of lung cancer patients
Fang Wei, Chien-Chung Lin,Szu-Chun Yang, Aron Joon, Ziding Feng, Gabriel Troche, Maruja E. Lira, David Chia, Mao Mao, Chung-Liang Ho, Wu-Chou Su, and David T. W. Wong

In patients with NSCLC, Electric Field–Induced Release and Measurement (EFIRM) can detect EGFR mutations directly in saliva. This enables clinicians to adjust their therapeutic strategies in a timely fashion, consequently improving the clinical outcome of EGFR-targeted therapy.

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Dry-mass sensing for microfluidics
T. Müller, D. A. White, and T. P. J. Knowles

The dry mass of analyte from microchannels is measured by means of spray-drying on an electromechanical sensor with nanogram sensitivity.

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THE MASTOCYTOSIS SOCIETY SURVEY ON MAST CELL DISORDERS: Part 2-Clinical Experiences, Co-Morbidities, Diet, Families and Opinions
aNancyRussell, DrPH, aSusanJennings, PhD, aBlairJennings, BS, aValerie Slee , RN, BSN, aLisa Sterling, BS, bMariana Castells, MD, PhD, FAAAAI,cPeter Valent, MD, bCem Akin, MD, PhD, FAAAAI

Mast cell diseases such as mastocytosis and mast cell activation syndromes involve abnormal proliferation or activation of these cells leading to many potentially debilitating symptoms. In order to determine the characteristics and experiences of people known or suspected to have a mast cell disorder, The Mastocytosis Society (TMS), a U.S. based patient advocacy, research and education organization, conducted a survey of patients.

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Specificity of highly potent miRNA inhibitors
Barbara Robertson, Andrew Dalby, Yuriy Fedorov, Jon Karpilow, Anastasia Khvorova1, Devin Leake, Annaleen Vermeulen

miRNA inhibitors are invaluable tools for elucidating the roles of miRNAs. However, potent inhibitors may also affect other miRNAs. To understand the potential cross-reactivity of miRNA inhibitors, various miRNA inhibitor designs were systematically tested. We demonstrate that mismatches both within and outside the seed region of the miRNA interfere with inhibition. Our findings indicate that features important for natural miRNA target recognition are also important for inhibitor specificity.

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Targeting Cancer Stem Cell-Related miRNAs for Prostate Cancer Therapy
ANSHIKA NIKITA SINGH, MEGHNA BARUAH, NEETI SHARMA

The poster focuses on the pivotal function of miRNAs in tumorigenesis by regulation of self renewal and apoptosis via cancer stem cell signalling pathways with special focus on their regulation of Epithelial to Mesenchymal transition in metastatic prostate cancer.

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Showing Results 11 - 20 of 1182
Scientific News
Chemical Tag Marks Future microRNAs for Processing, Study Shows
New research reveals how cells sort out the loops meant to encode small RNAs.
Blood Test Could Help Bowel Cancer Patients Avoid Drug Side-Effects
Manchester researchers have provided early evidence to suggest that a blood test could be used to identify bowel cancer patients that may benefit from more intensive chemotherapy.
Study Announces a Durable Vaccine for Ebola
Researchers from Plymouth University have led team which has developed a durable vaccine for Ebola together with a disseminating vaccine strategy.
Link Between Genetic Variation And Alcohol Dependence
The discovery could help scientists develop more effective drugs to combat alcoholism.
Changes In A Blood-Based Molecular Pathway Identified In Alzheimer’s
Study identifies increased activation of the contact system in plasma of Alzheimer’s patients.
Nanotechnology Platform For Treating Pancreatic Cancer
Scientists at UCLA’s California NanoSystems Institute and Jonsson Comprehensive Cancer Center have combined their nanotechnology expertise to create a new treatment that may solve some of the problems of using chemotherapy to treat pancreatic cancer.
Comparing The Genomes Of The Leprosy Bacteria
EPFL scientists have compared for the first time the genomes of the two bacteria species that cause leprosy. The study shows how the two species evolved from a common ancestor 13.9 million years ago, and offers new insights into their biology that could lead to new treatments.
Bright New Hope for Beating Deadly Hereditary Stomach and Breast Cancers
Researchers use genomic screening to search for vulnerabilities in the cancer cells.
Los Alamos Creates Bioinformatics Tool for Metagenome Analysis
‘GOTTCHA’ tool could aid ID of co-infections in medical samples.
Mechanically Stimulating Stem Cells
MIT biological engineering graduate student Frances Liu is studying ways to alter mechanical properties of cell environments to produce desired chemical outputs.
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