|A multi-resonances valveless micropump with high fluid transportation efficiency|
Ming-Che Hsieh, Min-Fan Huang, and An-Bang Wang
A multi-resonances valveless micropump equipping with inlet/outlet elastic chambers of intendedly-designed stiffness was successfully realized to solve the low efficiency problem. Besides, a theoretical model based on Hydraulic-electrical-Analogy was also proposed to precisely predict its characteristics of dynamic behavior.
|A novel multi-organ microfluidic chip: on the way to the complexity of a living organism|
Timur R Samatov, Svetlana A Tonevitskaya, Natalya Pulkova, Evgeny A Tonevitsky
A novel physiologically relevant multi-organ chip is developed capable of culturing up to six different organotypic models integrated into a single microfluidic circuit.
|ENZYME COATED MAGNETIC NANOPARTICLES FOR USE IN CONTINUOUS FLOW MICROFLUIDIC DEVICES|
Ferenc Ender, Diana Weiser, Andras Vitez, Laszlo Poppe
A novel Lab-on-a-Chip platform is presented incorporates micro-sized magnetic reaction cells capable of anchoring protein-coated MNPs addressable and selectively. Such platform allows the design of highly flexible and "programmable" execution of multienzyme processes for biocatalytic or diagnostic purposes.
|Continuous Collection of Stem Cells from a Human Placenta Perfusion Co-Culture|
John J.S. Cadwell & James C. Hardy
The potential for human placenta-derived cells to produce stem cells in a hollow fiber bioreactor co-culture system was investigated.
|Electric Field-Induced Release and Measurement (EFIRM) can detect EGFR mutations directly from body fluids of lung cancer patients|
Fang Wei, Chien-Chung Lin,Szu-Chun Yang, Aron Joon, Ziding Feng, Gabriel Troche, Maruja E. Lira, David Chia, Mao Mao, Chung-Liang Ho, Wu-Chou Su, and David T. W. Wong
In patients with NSCLC, Electric Field–Induced Release and Measurement (EFIRM) can detect EGFR mutations directly in saliva. This enables clinicians to adjust their therapeutic strategies in a timely fashion, consequently improving the clinical outcome of EGFR-targeted therapy.
|Dry-mass sensing for microfluidics|
T. Müller, D. A. White, and T. P. J. Knowles
The dry mass of analyte from microchannels is measured by means of spray-drying on an electromechanical sensor with nanogram sensitivity.
|THE MASTOCYTOSIS SOCIETY SURVEY ON MAST CELL DISORDERS: Part 2-Clinical Experiences, Co-Morbidities, Diet, Families and Opinions|
aNancyRussell, DrPH, aSusanJennings, PhD, aBlairJennings, BS, aValerie Slee , RN, BSN, aLisa Sterling, BS, bMariana Castells, MD, PhD, FAAAAI,cPeter Valent, MD, bCem Akin, MD, PhD, FAAAAI
Mast cell diseases such as mastocytosis and mast cell activation syndromes involve abnormal proliferation or activation of these cells leading to many potentially debilitating symptoms. In order to determine the characteristics and experiences of people known or suspected to have a mast cell disorder, The Mastocytosis Society (TMS), a U.S. based patient advocacy, research and education organization, conducted a survey of patients.
|Specificity of highly potent miRNA inhibitors|
Barbara Robertson, Andrew Dalby, Yuriy Fedorov, Jon Karpilow, Anastasia Khvorova1, Devin Leake, Annaleen Vermeulen
miRNA inhibitors are invaluable tools for elucidating the roles of miRNAs. However, potent inhibitors may also affect other miRNAs. To understand the potential cross-reactivity of miRNA inhibitors, various miRNA inhibitor designs were systematically tested. We demonstrate that mismatches both within and outside the seed region of the miRNA interfere with inhibition. Our findings indicate that features important for natural miRNA target recognition are also important for inhibitor specificity.
|Targeting Cancer Stem Cell-Related miRNAs for Prostate Cancer Therapy|
ANSHIKA NIKITA SINGH, MEGHNA BARUAH, NEETI SHARMA
The poster focuses on the pivotal function of miRNAs in tumorigenesis by regulation of self renewal and apoptosis via cancer stem cell signalling pathways with special focus on their regulation of Epithelial to Mesenchymal transition in metastatic prostate cancer.
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