Corporate Banner
Satellite Banner
Technology Networks Header
Thursday, October 23, 2014
 
Register | Sign in
Home Page>Posters

  Posters

Amino-Coated Metallofullerene Nanoparticles for Glioblastoma Mutiforme Tumor Detection
Tinghui Li , Susan. Murphy, Kanwarpal Bakshi, Steven LaConte, Zhi Sheng, and Harry Dorn

We report the preparation of a new functionalized trimetallic nitride endohedral metallofullerene, with a cage surface consisting of positively charged amino groups, which is expected to bind more efficiently to negatively charged cell phospholipid bi-layer cellular surfaces and will more readily undergo endocytosis. We now report that this Gd-nanoplatform when subsequently conjugated with an IL-13 peptide, (IL-13-Gd3N@C80(OH)x(NH2)y) exhibits enhanced targeting of U-251 GBM cell lines.

More Information
Liposomes and Nanoparticles as Delivery Vehicles for the Treatment of Lung Diseases
Raisa Kiseleva1, Jennifer Mulligan2, Carl Atkinson2, Rodney Schlossser2, Alexey Vertegel1

Targeted nanoparticle-based drug delivery to the lungs is an emerging area of interest for both scientists and medical workers because it allows better drug retention in the lungs and can provide prolonged drug release. In our study we investigated the potential of using liposomes and polymeric nanoparticles surface modified with a specific antibody as drug carriers for targeted drug delivery to the lungs.

More Information
Next Generation Multivalent PRINT Nanoparticle Vaccine Targeting Pneumococcal Disease
Shyam Rele,1 RiLee Robeson,1 Anton Beletskii,1 Jeremy Hansen,1 Meredith Earl,1 Gabe Fawcett,1* Marquita Lilly,1 Joseph Marchand,1 Michele Stone,1 Camille Bernasconi,1 Jinny Conley,1 Michael Hunter,1 Ramya Yadavalli,1 Nicole Meyer,1 Lara Kelly,1 Ben Yerxa,1 Jeff Maisonneuve,2 Mark Alderson,2 Frank Malinoski1

A new generation PRINT nanoparticle Pneumococcal vaccine matrix has been designed to mimic size and structural aspects of bacterial pathogens to efficiently present and deliver polysaccharide and protein antigens to elicit robust immune responses.

More Information
Print Nanoparticle Vaccine Carrying Bacterial Polysaccharide And Protein Antigens Induces Enhanced B- And T-Cell (Il-17) Immunity
Anton Beletskii,1 Camille Bernasconi,1 Jinny Conley, Meredith Earl,1 Gabe Fawcett,1 Jeremy Hansen,1 Lara Kelly,1 Marquita Lilly,1 Frank Malinoski,1 Joseph Marchand,1 Nicole Meyer,1 Shyam Rele,1 RiLee Robeson,1 Michele Stone,1 Ben Yerxa,1 Jeff Maisonneuve,2 Mark Alderson 2

Antigenic multivalent PRINT nanoparticle formulations leverage precise control of size, shape and composition, sterile filterability and scalable cGMP roll-to roll manufacturing to offering a low cost and simplified manufacturing advantage over traditional conjugate vaccines.

More Information
Significant Increase of Sensitivity on Rapid Influenza Antigen Assays Using Silver Amplification Immunochromatography.
Satoshi KIMURA1), Hideyoshi OHTO2), Hayato YAMAGUCHI1), Seiji FUKUOKA1), Emiko NAKAMA1), Akiko TERADA3), and Yoh UMEDA2)

We have developed a new rapid bed-side assay system for in vitro diagnosis of infectious diseases, using “silver amplification method”, an application of photography-developing technology. The automatic analyzer brings results in fifteen minutes, enhancing sensitivity up to 1000 times compared to the conventional immunochromatography. We applied the technology for diagnosis of hospitalized children. The analyzer was useful for rapid and precise diagnosis of influenza A and B.

More Information
NEXTflex™ qRNA-Seq™ Molecular Indexing for ChIP-Seq and RNA-Seq
Jan Risinger, Masoud Toloue Ph.D.

Most Next Generation Sequencing (NGS) library prep methods introduce sequence bias with the use of enzyme processing and fragmentation steps can introduce errors in the form of incorrect sequence and misrepresented copy number. With molecular indexed libraries, each molecule is tagged with a molecular index randomly chosen from ~10,000 combinations so that any two identical molecules become distinguishable (with odds of 10,000/1), and can be independently evaluated in later data analysis.

More Information
Side by Side: An Evaluation of 2D vs. 3D Cell Culture for High Throughput Screening in Drug Discovery
Sophie Quick 1,2, Sinead Knight 1, Jon Winter 3

•3D cell culture has the potential to provide a more physiologically relevant model compared to standard tissue culture plastic.
•From a screening perspective the technology offers the possibility of more predictive drug responses but has an increased cost.
•The question: is it possible and, more importantly, is it worthwhile moving towards screening in High Throughput using a 3D model?

More Information
High Throughput Screening in the European Lead Factory
S.P. van Helden, W.H. Rutjes, C.A.A. van Boeckel and J.H.M. van den Broek

This paper describes workflows that have been implemented at the screening centre of the European Lead Factory and presents screening statistics on the first 18 months of operation.

More Information
Use of a Microlitre Digital Liquid Handler for Screening Applications
Joby Jenkins, Gillian Lewis, Wayne Bowen

Digital dispensing offers researchers the most freedom for experimental design and sample placement with each microplate. It makes it relatively simple to plan and execute the most desirable experimental design and not one predicated by manual or automated liquid handling.

More Information
<< 1 2 3 4 5 6 7 >>
Showing Results 11 - 20 of 1052
Scientific News
Magnesium Cuts Diabetes Risk
Only about half of Americans get the recommended daily amount in their diet.
Major Step Forward in Understanding of Viruses
Scientists unlock exact structure of Hepatitis A virus.
TGAC Leads Research To Help Identify Animal-To-Human Transmitted Diseases
The Genome Analysis Centre (TGAC) will lead research into the development of bioinformatics to support the identification and characterisation of viruses through metagenomics.
Lab-developed Intestinal Organoids form Mature Human Tissue in Mice
Study produces unprecedented model to study intestinal diseases.
Study Investigates Inherent Contamination in Deep Well Microplates
Study gives data on microplates from numerous manufacturers based in Europe, USA and China.
Revalesio’s Drug Shows Promise in Treating Alzheimer’s
Multiple published research studies outline the potential for RNS60 to effectively treat Alzheimer’s disease by protecting neuronal function and restoring neuronal plasticity.
Shaking Up Cell Biology
Researchers focus in on decades old mystery.
Drinking Water Odors, Chemicals Above Health Standards Caused by 'Green Building' Plumbing
Several types of plastic pipes in eco-friendly green buildings in the United States have been found to leach chemicals into drinking water that can cause odors and sometimes exist at levels that may exceed health standards.
Fruit Fly Could Help Sniff Out Drugs and Bombs
Research from the University of Sussex has found a fly’s sense of smell could be used in new technology to detect drugs and bombs.
Nanoparticles Give up Forensic Secrets
Researchers from Switzerland have thrown light on the precise mechanisms responsible for the impressive ability of nanoparticles to detect fingermarks left at crime scenes.
Scroll Up
Scroll Down
Skyscraper Banner
Skyscraper Banner
Follow TechNetcom1 on Twitter
Technology Networks Ltd. on LinkedIn
Go to LabTube.tv