|An examination of specific cellular organelle-targeting nanotags using combined 3D Raman and SERS imaging |
Katherine Lau, Sarah McAughtrie, Karen Faulds, Duncan Graham
We investigated the specific targeting of endoplasmic reticulum and trans-Golgi network in Chinese hamster ovarian cells using functionalised nanotags. The targeting was examined using the combined 3D SERS and Raman imaging method.
|SOFT DEVICES FOR HEALTHCARE MONITORING APPLICATIONS|
Laura López, Carlos Carenas, Carme de Haro, Cristina Casellas, Elisenda Reixach, Marta Cot, Rosa Rodriguez, Paul Lacharmoise, Úrbez Santana
Printed Electronics allow the creation of new and innovative functionalized textile products, in the demanding and highly specialized world of Medical Devices. The main aim of this whole new sector is to produce wearable, conformable, flexible and low-cost textile-based devices bringing innovative solutions to different markets.
|The Power Decoder simulator for the evaluation of pooled shRNA screen performance|
Jesse Stombaugh, Abel Licon, Žaklina Strezoska, Joshua Stahl, Sarah Bael Anderson, Michael Banos, Anja van Brabant Smith, Amanda Birmingham, Annaleen Vermeulen
Power Decoder (written in R and Python) simulates shRNA pooled screening experiments in silico to allow for the estimation of a screen’s statistical power. Populations of shRNAs were engineered in such a way that the magnitude of depletion and enrichment was known, then using the negative binomial distribution, an in silico model was developed to successfully resemble data from an actual laboratory experiment.
|Building a Diverse and Experimentally-Curated Fragment Library|
Andrew Lowerson, Steven LaPlante, Patrick McCarren, and Michael Serrano-Wu
Presenting a new fragment collection with experimentally-determined aqueous solubility that will address a major source of false positives and attrition in fragment screening
|Polymer Microarrays for Biomaterial Development|
Simmonte, M.J.1, Dhaliwal, K.2, Cuschieri, K.3, Graham, S.V.4, Bradley, M.1
The application of polymer microarrays in the discovery of biocompatible and bioactive substrates. Progress towards biomaterial development for the treatment of SIRS (systemic inflammatory response syndrome), and improving cervical cytology.
|Knockdown of long noncoding RNAs in breast cancer |
1 Jennii Luu, 2 Jesper Maag, 1 Yanny Handoko, 3 Richard Redvers, 3,4 Robin L. Anderson, 5 Maren M. Gross , 2 Marcel E. Dinger, and 1,3 Kaylene J. Simpson 1 Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre; 2 Genome Informatics, The Kinghorn Cancer Centre, The Garvan Institute of Medical Research; 3 Metastasis Research Laboratory, Peter MacCallum Cancer Centre, 4 Sir Peter MacCallum Department of Oncology, University of Melbourne;
RNAi global collaboration study using Lincode siRNA in a primary screen of tumor and nontumor breast cell lines. Hundreds of lncRNAs are found to affect viability and cell morphology of breast cancer. Presented at Keystone Symposia on Long Noncoding RNAs: From Evolution to Function, Mar 15 - Mar 20, 2015.
|TGA/IST16/GC/MS coupling : an advanced technique for LLDPE structure interpretation|
Tiffany Marre1 ; Axel Bart1 ; Alain Delauzun1 ; Xavier Cardot1 ; Ronan Cozic1 ; Olivier Boyron2 ; Christophe Boisson2
An innovative TGA/IST16/GC/MS coupling is presented.
|DETERMINATION OF THE QUALITY OF ACTIVE INGREDIENTS IN PAIN KILLERS USING GC-MS|
Elizabeth N.M Murago1, Nathan Oyaro1, Anthony N. Gachanja, Onditi O. Anam, Felix M. Mawili, Steve Lancaster
From this study, the pain killers sampled were found to have large error bars suggesting that there exist counterfeit drugs in the market. The brands mostly affected for analysis of acetaminophen were panadol, action, P500, P5500, elymol and neladol. The error bars for caffeine analysis were quite low indicating that all tablets either counterfeit or original maintained the same amount of this active ingredient.
|DETERMINATION OF ESSENTIAL AND HEAVY METALS IN KENYAN HONEY BY ATOMIC ABSORPTION AND EMMISSION SPECTROSCOPY|
A. Mbiri, A. Onditi, N. Oyaro
Generally, honey samples recorded very low concentrations of As compared to the other heavy metals determined in this study. The highest concentration of As was recorded in honey sample from Nairobi with a value of 0.03±0.01 ppm. All the values recorded were within the KEBS permitted value of 0.5 ppm in food according to Kenya Bureaue of Standards, 1996.
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